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Dengshun Miao
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: English, Chinese
Bone
Stem Cells
Regeneration
Osteoporosis
Aging
Disease
Cellular Mechanisms
Research
Biology
Health
Areas of Focus
- Bone and Stem Cells
- Aging and Disease
Work Experience
- 1987-1994: Assistant Lecturer, Lecturer, Associate Professor at Suzhou Medical College
- 1999-2002: Postdoctoral Researcher at McGill University, Canada
- 2002-2005: Assistant Professor at McGill University, Canada
- 2005-present: Distinguished Professor at Nanjing Medical University
Academic Background & Achievements
- 1984-1987: Master's degree from Nanjing Medical University
- 1995-1998: PhD from University of Sheffield, UK
- Published 130 SCI papers with over 5000 citations
- Authored 4 English monographs
- Granted 2 international invention patents and 2 national invention patents
Publications
- 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis., Yang R, Chen J, Zhang J, Qin R, Wang R, Qiu Y, Mao Z, Goltzman D and Miao D*, 2019
- The Polycomb Protein Bmi1 Plays a Crucial Role in the Prevention of 1,25(OH)2 D Deficiency-Induced Bone Loss., Sun H, Qiao W, Cui M, Yang C, Wang R, Goltzman D, Jin J and Miao D*, 2019
- lncRNA UCA1 Predicts a Poor Prognosis and Regulates Cell Proliferation and Migration by Repressing p21 and SPRY1 Expression in GC., He X, Wang J, Chen J, Han L, Lu X, Miao D*, Yin D*, Geng Q* and Zhang E*, 2019
- Pyrroloquinoline Quinone Prevents Estrogen Deficiency-Induced Osteoporosis by Inhibiting Oxidative Stress and Osteocyte Senescence., Geng Q, Gao H, Yang R, Guo K and Miao D*, 2019
- 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling., Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, Goltzman D* and Miao D*, 2019
- Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Anti-Aging and Anti-Osteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress., Chen G, Zhang Y, Yu S, Sun W and Miao D*, 2019
- DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide., Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D and Miao D*, 2018
- Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition., Sun W, Qiao W, Zhou B, Hu Z, Yan Q, Wu J, Wang R, Zhang Q and Miao D*, 2018
- 1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice., Chen L, Yang R, Qiao W, Yuan X, Wang S, Goltzman D* and Miao D*, 2018
- BMI-1 Mediates Estrogen-Deficiency-Induced Bone Loss by Inhibiting Reactive Oxygen Species Accumulation and T Cell Activation., Li J, Wang Q, Yang R, Zhang J, Li X, Zhou X and Miao D*, 2017
- P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency., Jin J, Tao J, Gu X, Yu Z, Wang R, Zuo G, Li Q, Lv X and Miao D*, 2017
- Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment., Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, Yang X and Miao D*, 2016
- PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27., Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, Goltzman D and Miao D*, 2016
- CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders., Bai X, Miao D, Xiao S, Qiu D, St-Arnaud R, Petkovich M, Gupta A, Goltzman D and Karaplis AC*, 2016
Awards
- 1994: Outstanding Young Teacher in Jiangsu Province
- 2001: ASBMR Young Investigator Award
- 2007: Honorary Professor at the University of Hong Kong Faculty of Dentistry
- 2011: Jiangsu Province Science and Technology Award (Third Class)
- 2012: Jiangsu Province May 1st Labor Medal
- 2017: Jiangsu Province Science and Technology Award (Second Class)
