Professor | Xiaoqin Yuan | Asia Growth Partners

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Name	Xiaoqin Yuan
Contact Information	yuanxq@njmu.edu.cn
Language ability	Chinese, Japanese, English
Province	Jiangsu

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Name

Xiaoqin Yuan

Contact Information

yuanxq@njmu.edu.cn

Language ability

Chinese, Japanese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1997/9 - 2002/7 Bachelor: Nanjing Medical University, Clinical Medicine 2003/9 - 2007/9 Doctorate: Yamaguchi University, Biochemistry and Functional Proteomics
Work Experience	2008/4 - 2010/4 University of California, San Diego, Moores Cancer Center, Postdoctoral Researcher 2010/5 - 2011/7 Nanjing University, Model Animal Research Institute, Postdoctoral Researcher 2011/9 - 2022/6 Nanjing Medical University, School of Basic Medical Sciences, Associate Professor 2022/7 - Present Nanjing Medical University, School of Basic Medical Sciences, Professor

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1997/9 - 2002/7 Bachelor: Nanjing Medical University, Clinical Medicine
2003/9 - 2007/9 Doctorate: Yamaguchi University, Biochemistry and Functional Proteomics

Work Experience

2008/4 - 2010/4 University of California, San Diego, Moores Cancer Center, Postdoctoral Researcher
2010/5 - 2011/7 Nanjing University, Model Animal Research Institute, Postdoctoral Researcher
2011/9 - 2022/6 Nanjing Medical University, School of Basic Medical Sciences, Associate Professor
2022/7 - Present Nanjing Medical University, School of Basic Medical Sciences, Professor

Areas of Focus	Research on the pathogenesis and prevention mechanisms of tumors Research on the pathogenesis of digestive system tumors and exploration of possible diagnostic and therapeutic targets Research on tumor drug resistance mechanisms and development of inhibitors targeting related signaling pathways Exploration of the role and mechanism of healthy lifestyle and dietary habits in the prevention of tumors, especially colorectal cancer
Publications	RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP, Zheng D, Cao M, Zuo S, Xia X, Zhi C, Lin Y, Deng S, Yuan X, 2022 Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9, Cao M, Wang Y, Xiao Y, Zheng D, Zhi C, Xia X, Yuan X, 2021 Pseudogene KRT17P3 drives cisplatin resistance of human NSCLC cells by modulating miR-497-5p/mTOR, Hou Z, Wang Y, Xia N, Lv T, Yuan X, Song Y, 2021 Circ-100290 Positively Regulates Angiogenesis Induced by Conditioned Medium of Human Amnion-Derived Mesenchymal Stem Cells Through miR-449a/eNOS and miR-449a/VEGFA Axes, Tang Z, Wu X, Hu L, Xiao Y, Tan J, Zuo S, Shen M, Yuan X, 2020 Long Non-coding RNA MEG3 Activated by Vitamin D Suppresses Glycolysis in Colorectal Cancer via Promoting c-Myc Degradation, Zuo S, Wu L, Wang Y, Yuan X, 2020 The long noncoding RNA LUCAT1 promotes CRC tumorigenesis by targeting RPL40-MDM2-p53 pathway through binding with UBA52, Zhou Q, Hou Z, Zuo S, Zhou X, Feng Y, Sun Y, Yuan X, 2019 1,25(OH)2D3 deficiency‑induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model, Zhu W, Yan J, Zhi C, Zhou Q, Yuan X, 2019 1,25(OH)2D3通过调控连接蛋白的表达缓解DSS诱导的小鼠结肠炎, 朱文静，颜家耀，周倩雯，龚子旋，袁小琴, 2018

Areas of Focus

Research on the pathogenesis and prevention mechanisms of tumors
Research on the pathogenesis of digestive system tumors and exploration of possible diagnostic and therapeutic targets
Research on tumor drug resistance mechanisms and development of inhibitors targeting related signaling pathways
Exploration of the role and mechanism of healthy lifestyle and dietary habits in the prevention of tumors, especially colorectal cancer

Publications

RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP, Zheng D, Cao M, Zuo S, Xia X, Zhi C, Lin Y, Deng S, Yuan X, 2022
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9, Cao M, Wang Y, Xiao Y, Zheng D, Zhi C, Xia X, Yuan X, 2021
Pseudogene KRT17P3 drives cisplatin resistance of human NSCLC cells by modulating miR-497-5p/mTOR, Hou Z, Wang Y, Xia N, Lv T, Yuan X, Song Y, 2021
Circ-100290 Positively Regulates Angiogenesis Induced by Conditioned Medium of Human Amnion-Derived Mesenchymal Stem Cells Through miR-449a/eNOS and miR-449a/VEGFA Axes, Tang Z, Wu X, Hu L, Xiao Y, Tan J, Zuo S, Shen M, Yuan X, 2020
Long Non-coding RNA MEG3 Activated by Vitamin D Suppresses Glycolysis in Colorectal Cancer via Promoting c-Myc Degradation, Zuo S, Wu L, Wang Y, Yuan X, 2020
The long noncoding RNA LUCAT1 promotes CRC tumorigenesis by targeting RPL40-MDM2-p53 pathway through binding with UBA52, Zhou Q, Hou Z, Zuo S, Zhou X, Feng Y, Sun Y, Yuan X, 2019
1,25(OH)2D3 deficiency‑induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model, Zhu W, Yan J, Zhi C, Zhou Q, Yuan X, 2019
1,25(OH)2D3通过调控连接蛋白的表达缓解DSS诱导的小鼠结肠炎, 朱文静，颜家耀，周倩雯，龚子旋，袁小琴, 2018

Tumor Pathogenesis Prevention Digestive System Diagnostic Targets Therapeutic Targets Drug Resistance Signaling Pathways Healthy Lifestyle Colorectal Cancer

Fengyan Han - Guangzhou Medical University

Xuenong Li - Southern Medical University

Jun Zhou - Southern Medical University

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