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Xiaoqin Yuan
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: Chinese, Japanese, English
Tumor
Pathogenesis
Prevention
Digestive System
Diagnostic Targets
Therapeutic Targets
Drug Resistance
Signaling Pathways
Healthy Lifestyle
Colorectal Cancer
Areas of Focus
- Research on the pathogenesis and prevention mechanisms of tumors
- Research on the pathogenesis of digestive system tumors and exploration of possible diagnostic and therapeutic targets
- Research on tumor drug resistance mechanisms and development of inhibitors targeting related signaling pathways
- Exploration of the role and mechanism of healthy lifestyle and dietary habits in the prevention of tumors, especially colorectal cancer
Work Experience
- 2008/4 - 2010/4 University of California, San Diego, Moores Cancer Center, Postdoctoral Researcher
- 2010/5 - 2011/7 Nanjing University, Model Animal Research Institute, Postdoctoral Researcher
- 2011/9 - 2022/6 Nanjing Medical University, School of Basic Medical Sciences, Associate Professor
- 2022/7 - Present Nanjing Medical University, School of Basic Medical Sciences, Professor
Academic Background & Achievements
- 1997/9 - 2002/7 Bachelor: Nanjing Medical University, Clinical Medicine
- 2003/9 - 2007/9 Doctorate: Yamaguchi University, Biochemistry and Functional Proteomics
Publications
- RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP, Zheng D, Cao M, Zuo S, Xia X, Zhi C, Lin Y, Deng S, Yuan X, 2022
- Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9, Cao M, Wang Y, Xiao Y, Zheng D, Zhi C, Xia X, Yuan X, 2021
- Pseudogene KRT17P3 drives cisplatin resistance of human NSCLC cells by modulating miR-497-5p/mTOR, Hou Z, Wang Y, Xia N, Lv T, Yuan X, Song Y, 2021
- Circ-100290 Positively Regulates Angiogenesis Induced by Conditioned Medium of Human Amnion-Derived Mesenchymal Stem Cells Through miR-449a/eNOS and miR-449a/VEGFA Axes, Tang Z, Wu X, Hu L, Xiao Y, Tan J, Zuo S, Shen M, Yuan X, 2020
- Long Non-coding RNA MEG3 Activated by Vitamin D Suppresses Glycolysis in Colorectal Cancer via Promoting c-Myc Degradation, Zuo S, Wu L, Wang Y, Yuan X, 2020
- The long noncoding RNA LUCAT1 promotes CRC tumorigenesis by targeting RPL40-MDM2-p53 pathway through binding with UBA52, Zhou Q, Hou Z, Zuo S, Zhou X, Feng Y, Sun Y, Yuan X, 2019
- 1,25(OH)2D3 deficiency‑induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model, Zhu W, Yan J, Zhi C, Zhou Q, Yuan X, 2019
- 1,25(OH)2D3通过调控连接蛋白的表达缓解DSS诱导的小鼠结肠炎, 朱文静，颜家耀，周倩雯，龚子旋，袁小琴, 2018
