Professor | Jian Yang | Asia Growth Partners

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Name	Jian Yang
Contact Information	jianyang@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Jian Yang

Contact Information

jianyang@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1979-1984 Bachelor's Degree: Nanjing Medical University 1987-1990 Master's Degree in Pharmacology: Nanjing University of Chinese Medicine 2002-2008 Doctorate in Pharmacology: Nanjing Medical University Published over 30 SCI papers as first or corresponding author
Work Experience	1990-2000 - Jiangsu Workers' Medical University - Lecturer, Associate Professor 2001-present - Nanjing Medical University, School of Basic Medical Sciences - Associate Professor, Professor 2004-2008 - University of Rhode Island, College of Pharmacy - Visiting Scholar, Postdoctoral Researcher
Awards	Nanjing Medical University 'Three Educators' Model' (2016) Yangtze River Teaching Award Excellence Award (2014) Third Prize in National Undergraduate Basic Medical Innovation Forum and Experimental Design Competition (2013) Jiangsu Province 'Six Talent Peaks' (Category B) High-level Talent Training Object (2008) Military Science and Technology Progress Third Prize (2003)

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1979-1984 Bachelor's Degree: Nanjing Medical University
1987-1990 Master's Degree in Pharmacology: Nanjing University of Chinese Medicine
2002-2008 Doctorate in Pharmacology: Nanjing Medical University
Published over 30 SCI papers as first or corresponding author

Work Experience

1990-2000 - Jiangsu Workers' Medical University - Lecturer, Associate Professor
2001-present - Nanjing Medical University, School of Basic Medical Sciences - Associate Professor, Professor
2004-2008 - University of Rhode Island, College of Pharmacy - Visiting Scholar, Postdoctoral Researcher

Awards

Nanjing Medical University 'Three Educators' Model' (2016)
Yangtze River Teaching Award Excellence Award (2014)
Third Prize in National Undergraduate Basic Medical Innovation Forum and Experimental Design Competition (2013)
Jiangsu Province 'Six Talent Peaks' (Category B) High-level Talent Training Object (2008)
Military Science and Technology Progress Third Prize (2003)

Areas of Focus	Clinical Pharmacology
Publications	The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling, Zhu Z, Wu Y, Zhang Z, Ge D, Lu M, Liu W, Shan E, Hu G, Hiroaki H, Yang J, 2019 17β-estradiol suppresses carboxylesterases by activating c-Jun/AP-1 pathway in primary human and mouse hepatocytes, Wu L, Hafiz MZ, Guan Y, He S, Xiong J, Liu W, Yan B, Li X, Yang J, 2018 Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling, Li XM, Huang D, Yu Q, Yang J, Yao J, 2018 Icariin protects against glucocorticoid induced osteoporosis, increases the expression of the bone enhancer DEC1 and modulates the PI3K/Akt/GSK3β/β-catenin integrated signaling pathway, Hu J, Mao Z, He S, Zhan Y, Ning R, Liu W, Yan B, Yang J, 2017 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway, Zhu Z, Wang YW, Ge DH, Lu M, Liu W, Xiong J, Hu G, Li XP, Yang J, 2017 Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes, Ning R, Zhan Y, He S, Hu J, Zhu Z, Hu G, Yan B, Yang J, Liu W, 2017 Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells, Liu W, Ning R, Chen RN, Huang XF, Dai QS, Hu JH, Wang YW, Wu LL, Xiong J, Hu G, Guo QL, Yang J, Wang H, 2016 Gambogic acid suppresses cytochrome P450 3A4 by downregulating pregnane X receptor and up-regulating DEC1 in human hepatoma HepG2 cells, Wei Liu, Rui Ning, Rui-Ni Chen, Jin-Hua Hu, Hai-Yan Gui, Yu-Wen Wang, Jie Liu, Gang Hu, Jian Yang* and Qing-Long Guo*, 2015

Areas of Focus

Clinical Pharmacology

Publications

The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling, Zhu Z, Wu Y, Zhang Z, Ge D, Lu M, Liu W, Shan E, Hu G, Hiroaki H, Yang J*, 2019
17β-estradiol suppresses carboxylesterases by activating c-Jun/AP-1 pathway in primary human and mouse hepatocytes, Wu L, Hafiz MZ, Guan Y, He S, Xiong J, Liu W, Yan B, Li X, Yang J*, 2018
Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling, Li XM, Huang D, Yu Q, Yang J*, Yao J*, 2018
Icariin protects against glucocorticoid induced osteoporosis, increases the expression of the bone enhancer DEC1 and modulates the PI3K/Akt/GSK3β/β-catenin integrated signaling pathway, Hu J, Mao Z, He S, Zhan Y, Ning R, Liu W, Yan B, Yang J*, 2017
Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway, Zhu Z, Wang YW, Ge DH, Lu M, Liu W, Xiong J, Hu G, Li XP, Yang J*, 2017
Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes, Ning R, Zhan Y, He S, Hu J, Zhu Z, Hu G, Yan B, Yang J*, Liu W*, 2017
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells, Liu W, Ning R, Chen RN, Huang XF, Dai QS, Hu JH, Wang YW, Wu LL, Xiong J, Hu G, Guo QL, Yang J*, Wang H*, 2016
Gambogic acid suppresses cytochrome P450 3A4 by downregulating pregnane X receptor and up-regulating DEC1 in human hepatoma HepG2 cells, Wei Liu, Rui Ning, Rui-Ni Chen, Jin-Hua Hu, Hai-Yan Gui, Yu-Wen Wang, Jie Liu, Gang Hu, Jian Yang* and Qing-Long Guo*, 2015

Transcription Factor Dec1 Drug Metabolism Fat Metabolism Bone Metabolism Metabolic Diseases Clinical Pharmacology Pharmacology Teaching Research Nih Projects

Jinpeng Sun - Peking University

Ji Yanxiao - Wuhan University

Yanyong Xu - Fudan University

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