Professor | Xiao Ming | Asia Growth Partners

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Name	Xiao Ming
Language ability	Chinese, English
Province	Jiangsu

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Name

Xiao Ming

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2002.9–2005.7 PhD in Pharmacology: Nanjing Medical University 1997.9–2001.7 Master's in Human Anatomy and Embryology: Nanjing Medical University 1990.9–1995.7 Bachelor's in Clinical Medicine: Nanjing Medical University
Work Experience	2015.10-present - Nanjing Medical University, School of Basic Medical Sciences, Department of Pharmacology, Jiangsu Key Laboratory of Neurodegenerative Diseases - Professor 2012.9-2015.9 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Professor 2006.9-2012.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Associate Professor 2002.8-2005.6 - University of Louisville, Department of Neuroscience and Anatomy - Visiting Scholar 2001.9-2006.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Lecturer 1995.8-2001.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Assistant Lecturer
Awards	2016: Jiangsu Science and Technology Award, Third Prize, for research on vascular-immune abnormal mechanisms in Alzheimer's disease 2016: Jiangsu Educational Science Research Achievement, Second Prize, for research on the role of astrocytes in neurodegenerative diseases

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2002.9–2005.7 PhD in Pharmacology: Nanjing Medical University
1997.9–2001.7 Master's in Human Anatomy and Embryology: Nanjing Medical University
1990.9–1995.7 Bachelor's in Clinical Medicine: Nanjing Medical University

Work Experience

2015.10-present - Nanjing Medical University, School of Basic Medical Sciences, Department of Pharmacology, Jiangsu Key Laboratory of Neurodegenerative Diseases - Professor
2012.9-2015.9 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Professor
2006.9-2012.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Associate Professor
2002.8-2005.6 - University of Louisville, Department of Neuroscience and Anatomy - Visiting Scholar
2001.9-2006.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Lecturer
1995.8-2001.8 - Nanjing Medical University, School of Basic Medical Sciences, Department of Human Anatomy - Assistant Lecturer

Awards

2016: Jiangsu Science and Technology Award, Third Prize, for research on vascular-immune abnormal mechanisms in Alzheimer's disease
2016: Jiangsu Educational Science Research Achievement, Second Prize, for research on the role of astrocytes in neurodegenerative diseases

Areas of Focus	Neurodegenerative Diseases Alzheimer's Disease Astrocyte Function Aquaporin-4 Glymphatic System
Publications	Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance., Feng W, Zhang Y, Wang Z, Xu H, Wu T, Marshall C, Gao J, Xiao M, 2020 Blocking meningeal lymphatic drainage aggravates Parkinson's disease-like pathology in mice overexpressing mutated α-synuclein., Zou W, Pu T, Feng W, Lu M, Zheng Y, Du R, Xiao M, Hu G, 2019 Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice., Zhang H, Wu J, Wu J, Fan Q, Zhou J, Wu J, Liu S, Zang J, Ye J, Xiao M, Tian T, Gao J, 2019 Deep cervical lymph node ligation aggravates AD-like pathology of APP/PS1 mice., Wang L, Zhang Y, Zhao Y, Marshall C, Wu T, Xiao M, 2019 Aquaporin-4-dependent glymphatic solute transport in the rodent brain., Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, Plog BA, Thrane AS, Lundgaard I, Abe Y, Yasui M, Thomas JH, Xiao M, Hirase H, Asokan A, Iliff JJ, Nedergaard M, 2018 Enriched Physical Environment Attenuates Spatial and Social Memory Impairments of Aged Socially Isolated Mice., Wang L, Cao M, Pu T, Huang H, Marshall C, Xiao M, 2018 Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain., Chen Y, Yin M, Cao X, Hu G, Xiao M, 2018 Enriched physical environment reverses spatial cognitive impairment of socially isolated APPswe/PS1dE9 transgenic mice before amyloidosis onset., Cao M, Hu PP, Zhang YL, Yan YX, Shields CB, Zhang YP, Hu G, Xiao M, 2018 Early enriched physical environment reverses impairments of the hippocampus, but not medial prefrontal cortex, of socially-isolated mice., Cao M, Pu T, Wang L, Marshall C, He H, Hu G, Xiao M, 2017 Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis., Xu ZQ, Huang H, Chen YL, Gao YY, Xu J, Marshall C, Cai ZY, Xiao M, 2016 Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits., Xu Z, Xiao N, Chen Y, Huang H, Marshall C, Gao J, Cai Z, Wu T, Hu G, Xiao M, 2015 Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 Mice., Huang H, Wang L, Cao M, Marshall C, Gao J, Xiao N, Hu G, Xiao M, 2015 Aquaporin-4 mitigates retrograde degeneration of rubrospinal neurons by facilitating edema clearance and glial scar formation after spinal cord injury in mice., Wu Q, Zhang YJ, Gao JY, Li XM, Kong H, Zhang YP, Xiao M, Shields CB, Hu G, 2014 Calcium sensing receptor absence delays postnatal brain development via direct and indirect mechanisms., Liu XL, Lu YS, Gao JY, Marshall C, Xiao M, Miao DS, Karaplis A, Goltzman D, Ding J, 2013 Aquaporin-4 mediates astrocyte response to β-amyloid., Yang W, Wu Q, Yuan C, Gao J, Xiao M, Gu M, Ding J, Hu G, 2012 Aquaporin-4 deficiency exacerbates brain oxidative damage and memory deficits induced by long-term ovarian hormone deprivation and D-galactose injection., Liu L, Lu Y, Kong H, Li L, Marshall C, Xiao M, Ding J, Gao J, Hu G, 2012

Areas of Focus

Neurodegenerative Diseases
Alzheimer's Disease
Astrocyte Function
Aquaporin-4
Glymphatic System

Publications

Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance., Feng W, Zhang Y, Wang Z, Xu H, Wu T, Marshall C, Gao J, Xiao M, 2020
Blocking meningeal lymphatic drainage aggravates Parkinson's disease-like pathology in mice overexpressing mutated α-synuclein., Zou W, Pu T, Feng W, Lu M, Zheng Y, Du R, Xiao M, Hu G, 2019
Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice., Zhang H, Wu J, Wu J, Fan Q, Zhou J, Wu J, Liu S, Zang J, Ye J, Xiao M, Tian T, Gao J, 2019
Deep cervical lymph node ligation aggravates AD-like pathology of APP/PS1 mice., Wang L, Zhang Y, Zhao Y, Marshall C, Wu T, Xiao M, 2019
Aquaporin-4-dependent glymphatic solute transport in the rodent brain., Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, Plog BA, Thrane AS, Lundgaard I, Abe Y, Yasui M, Thomas JH, Xiao M, Hirase H, Asokan A, Iliff JJ, Nedergaard M, 2018
Enriched Physical Environment Attenuates Spatial and Social Memory Impairments of Aged Socially Isolated Mice., Wang L, Cao M, Pu T, Huang H, Marshall C, Xiao M, 2018
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain., Chen Y, Yin M, Cao X, Hu G, Xiao M, 2018
Enriched physical environment reverses spatial cognitive impairment of socially isolated APPswe/PS1dE9 transgenic mice before amyloidosis onset., Cao M, Hu PP, Zhang YL, Yan YX, Shields CB, Zhang YP, Hu G, Xiao M, 2018
Early enriched physical environment reverses impairments of the hippocampus, but not medial prefrontal cortex, of socially-isolated mice., Cao M, Pu T, Wang L, Marshall C, He H, Hu G, Xiao M, 2017
Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis., Xu ZQ, Huang H, Chen YL, Gao YY, Xu J, Marshall C, Cai ZY, Xiao M, 2016
Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits., Xu Z, Xiao N, Chen Y, Huang H, Marshall C, Gao J, Cai Z, Wu T, Hu G, Xiao M, 2015
Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 Mice., Huang H, Wang L, Cao M, Marshall C, Gao J, Xiao N, Hu G, Xiao M, 2015
Aquaporin-4 mitigates retrograde degeneration of rubrospinal neurons by facilitating edema clearance and glial scar formation after spinal cord injury in mice., Wu Q, Zhang YJ, Gao JY, Li XM, Kong H, Zhang YP, Xiao M, Shields CB, Hu G, 2014
Calcium sensing receptor absence delays postnatal brain development via direct and indirect mechanisms., Liu XL, Lu YS, Gao JY, Marshall C, Xiao M, Miao DS, Karaplis A, Goltzman D, Ding J, 2013
Aquaporin-4 mediates astrocyte response to β-amyloid., Yang W, Wu Q, Yuan C, Gao J, Xiao M, Gu M, Ding J, Hu G, 2012
Aquaporin-4 deficiency exacerbates brain oxidative damage and memory deficits induced by long-term ovarian hormone deprivation and D-galactose injection., Liu L, Lu Y, Kong H, Li L, Marshall C, Xiao M, Ding J, Gao J, Hu G, 2012

Neurodegeneration Alzheimer'S Astrocytes Aquaporin Glymphatic Pathology Immunology Neuroscience Research Mechanisms

Xian Wang - Peking University

Yi Ming - Peking University

Yan Zhang - Peking University

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