Professor | Juejin Wang | Asia Growth Partners

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Name	Juejin Wang
Contact Information	juejinwang@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Juejin Wang

Contact Information

juejinwang@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2000-2005: Bachelor's degree in Clinical Medicine, Nanjing Medical University 2005-2010: PhD in Pharmacology, School of Basic Medicine, Nanjing Medical University Published over ten first/corresponding author papers in high-impact journals Led five National Natural Science Foundation projects
Work Experience	2008-2010: Research Assistant, National Neuroscience Institute/National University of Singapore 2010-2012: Postdoctoral Researcher, National University of Singapore 2012-2019: Associate Professor, Department of Physiology, School of Basic Medicine, Nanjing Medical University 2016-2017: Postdoctoral Researcher, Cleveland Clinic, USA 2019-present: Professor, Department of Physiology, School of Basic Medicine, Nanjing Medical University
Awards	2018: Second Prize in Jiangsu Physiology Lecture Competition 2018: Second Prize in Youth Forum at Jiucheng International Cardiovascular Physiology Conference 2020: First Friendship Award of Nanjing Medical University 2021: Special Prize in the Second Teaching Innovation Competition of Nanjing Medical University

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2000-2005: Bachelor's degree in Clinical Medicine, Nanjing Medical University
2005-2010: PhD in Pharmacology, School of Basic Medicine, Nanjing Medical University
Published over ten first/corresponding author papers in high-impact journals
Led five National Natural Science Foundation projects

Work Experience

2008-2010: Research Assistant, National Neuroscience Institute/National University of Singapore
2010-2012: Postdoctoral Researcher, National University of Singapore
2012-2019: Associate Professor, Department of Physiology, School of Basic Medicine, Nanjing Medical University
2016-2017: Postdoctoral Researcher, Cleveland Clinic, USA
2019-present: Professor, Department of Physiology, School of Basic Medicine, Nanjing Medical University

Awards

2018: Second Prize in Jiangsu Physiology Lecture Competition
2018: Second Prize in Youth Forum at Jiucheng International Cardiovascular Physiology Conference
2020: First Friendship Award of Nanjing Medical University
2021: Special Prize in the Second Teaching Innovation Competition of Nanjing Medical University

Areas of Focus	Ion channel diseases Role and mechanism of ion channels in cardiovascular diseases
Publications	Aberrant splicing of CaV1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia., Hou W, Yin S, Li P, Zhang L, Chen T, Qin D, Mustafa AU, Liu C, Song M, Qiu C, Xiong X, Wang J., 2024 Dysregulated Rbfox2 produces aberrant splicing of CaV1.2 calcium channel in diabetes-induced cardiac hypertrophy., Li P, Qin D, Chen T, Hou W, Song X, Yin S, Song M, Fernando WCHA, Chen X, Sun Y, Wang J., 2023 Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension., Song M, Hou W, Mustafa AU, Li P, Lei J, Zhou Y, Ji L, Sun Y, Zhou H, Xu Y, Wang J., 2022 A novel mutation in KCNH2 yields loss-of-function of hERG potassium channel in long QT syndrome 2., Gu K#, Qian D#, Qin H, Cui C, Fernando WCHA, Wang D, Wang J, Cao K, Chen M., 2021 Aberrant exon 8/8a splicing by downregulated PTBP (Polypyrimidine Tract-Binding Protein) 1 increases CaV1.2 dihydropyridine resistance to attenuate vasodilation., Lei J#, Liu X#, Song M, Zhou Y, Fan J, Shen X, Xu X, Kapoor I, Zhu G, Wang J., 2020 Galectin-1 attenuates cardiomyocyte hypertrophy through splice-variant specific modulation of CaV1.2 calcium channel., Fan J#, Fan W#, Lei J, Zhou Y, Xu H, Kapoor I, Zhu G, Wang J., 2019 Mutations in voltage-gated L-type calcium channel: implications in cardiac arrhythmia., Zhang Q#, Chen J#, Qin Y, Wang J, Zhou L., 2018 Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure., Wang J#, Li G#, Yu D, Wong YP, Yong TF, Liang MC, Liao P, Foo R, Hoppe UC, Soong TW., 2018 Aberrant splicing induced by dysregulated Rbfox2 produces enhanced function of CaV1.2 calcium channel and vascular myogenic tone in hypertension., Zhou Y#, Fan J#, Zhu H, Ji L, Fan W, Kapoor I, Wang Y, Wang Y, Zhu G, Wang J., 2017 Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic., Li G#, Wang J#, Liao P, Bartels P, Zhang H, Yu D, Liang MC, Poh KK, Yu CY, Jiang F, Yong TF, Wong YP, Hu Z, Huang H, Zhang G, Galupo MJ, Bian JS, Ponniah S, Trasti SL, See K, Foo R, Hoppe UC, Herzig S, Soong TW., 2017 Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7., Ji L#, Zhu H#, Chen H, Fan W, Chen J, Chen J, Zhu G, Wang J., 2015 Splice variant specific modulation of CaV1.2 calcium channel by galectin-1 regulates arterial constriction., Wang J, Thio SS, Yang SS, Yu D, Yu CY, Wong YP, Liao P, Li S, Soong TW*., 2011

Areas of Focus

Ion channel diseases
Role and mechanism of ion channels in cardiovascular diseases

Publications

Aberrant splicing of CaV1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia., Hou W, Yin S, Li P, Zhang L, Chen T, Qin D, Mustafa AU, Liu C, Song M, Qiu C, Xiong X*, Wang J*., 2024
Dysregulated Rbfox2 produces aberrant splicing of CaV1.2 calcium channel in diabetes-induced cardiac hypertrophy., Li P, Qin D, Chen T, Hou W, Song X, Yin S, Song M, Fernando WCHA, Chen X, Sun Y*, Wang J*., 2023
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension., Song M, Hou W, Mustafa AU, Li P, Lei J, Zhou Y, Ji L, Sun Y, Zhou H*, Xu Y*, Wang J*., 2022
A novel mutation in KCNH2 yields loss-of-function of hERG potassium channel in long QT syndrome 2., Gu K#, Qian D#, Qin H, Cui C, Fernando WCHA, Wang D, Wang J*, Cao K*, Chen M*., 2021
Aberrant exon 8/8a splicing by downregulated PTBP (Polypyrimidine Tract-Binding Protein) 1 increases CaV1.2 dihydropyridine resistance to attenuate vasodilation., Lei J#, Liu X#, Song M, Zhou Y, Fan J, Shen X, Xu X, Kapoor I, Zhu G, Wang J*., 2020
Galectin-1 attenuates cardiomyocyte hypertrophy through splice-variant specific modulation of CaV1.2 calcium channel., Fan J#, Fan W#, Lei J, Zhou Y, Xu H, Kapoor I, Zhu G, Wang J*., 2019
Mutations in voltage-gated L-type calcium channel: implications in cardiac arrhythmia., Zhang Q#, Chen J#, Qin Y, Wang J*, Zhou L*., 2018
Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure., Wang J#, Li G#, Yu D, Wong YP, Yong TF, Liang MC, Liao P, Foo R, Hoppe UC, Soong TW*., 2018
Aberrant splicing induced by dysregulated Rbfox2 produces enhanced function of CaV1.2 calcium channel and vascular myogenic tone in hypertension., Zhou Y#, Fan J#, Zhu H, Ji L, Fan W, Kapoor I, Wang Y, Wang Y, Zhu G, Wang J*., 2017
Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic., Li G#, Wang J#, Liao P, Bartels P, Zhang H, Yu D, Liang MC, Poh KK, Yu CY, Jiang F, Yong TF, Wong YP, Hu Z, Huang H, Zhang G, Galupo MJ, Bian JS, Ponniah S, Trasti SL, See K, Foo R, Hoppe UC, Herzig S, Soong TW*., 2017
Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7., Ji L#, Zhu H#, Chen H, Fan W, Chen J, Chen J, Zhu G, Wang J*., 2015
Splice variant specific modulation of CaV1.2 calcium channel by galectin-1 regulates arterial constriction., Wang J, Thio SS, Yang SS, Yu D, Yu CY, Wong YP, Liao P, Li S, Soong TW*., 2011

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