Areas of Focus
- Molecular cardiovascular research
- Metabolic disorders and diseases
- Genetically engineered hamster models
Work Experience
- 2008/11-2012/7 - UT Southwestern Medical Center, Department of Molecular Genetics, Postdoctoral Researcher
- 2012/8-2015/6 - UT Southwestern Medical Center, Department of Molecular Genetics, Lecturer
- 2015/7-2019/8 - UT Southwestern Medical Center, Department of Molecular Genetics, Assistant Professor
- 2019/11-present - Peking University, Cardiovascular Research Institute, Assistant Professor / PI
Academic Background & Achievements
- 1999/9-2003/7 Bachelor: Peking University, School of Pharmacy
- 2003/9-2008/7 PhD: Peking University, Physiology
- Published in high-impact journals such as Circulation Research and Science Signaling
Publications
- CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis, Shi H, Guo J, Yu Q, Hou X, Liu L, Gao M, Wei L, Zhang L, Huang W, Wang Y, Liu G, Tontonoz P, Xian X, 2022
- Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia, Xu Y, Guo J, Zhang L, Miao G, Lai P, Zhang W, Liu L, Hou X, Wang Y, Huang W, Liu G, Gao M, Xian X, 2022
Awards
- 2020: Outstanding Young Talent Award from the Chinese Society for Laboratory Animal Science
- 2021: National Overseas High-level Talents Youth Project