Upload Avatar (500 x 500)
Yujie Sun
Basic Medical Sciences
Nanjing Medical University
Jiangsu
Language: English, Chinese, German
Enhancer Elements
Regulatory Functions
Molecular Mechanisms
Genetic Variations
Tumor Biology
Drug Resistance
Epigenetics
Cancer Research
Gene Expression
Biomarkers
Areas of Focus
- Regulatory functions of enhancer elements, molecular mechanisms, and genetic variations in tumor biology
- Molecular biology and epigenetic mechanisms of tumor drug resistance
Work Experience
- 2003-present - Nanjing Medical University - Professor
- 1996-2003 - City of Hope National Medical Center, USA - Postdoctoral Researcher
- 1987-1991 - Nanjing Medical University - Assistant Lecturer
- 1981-1984 - Jiangsu Cancer Hospital - Research Assistant
Academic Background & Achievements
- 2003-present: Professor at Nanjing Medical University
- 1996-2003: Postdoctoral Researcher at City of Hope National Medical Center, USA
- 1991-1996: PhD in Human Genetics from University of Würzburg, Germany
- 1984-1987: Master's in Medical Genetics from Tongji Medical University
- 1981-1984: Research Assistant at Jiangsu Cancer Hospital
Publications
- The inherited variations of a p53-responsive-enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression., Lipei Shao, Xianglin Zuo, Yin Yang, Yu Zhang, Nan Yang, Bin Shen, Jianying Wang, Xuchun Wang, Ruilei, Guangfu Jin, Dawei Yu, Yuan Chen, Luan Sun, Zhen Li, Qiaofen Fu, Zhibin Hu, Xiao Han, Xin Song, Hongbin Shen, Yujie Sun., 2019
- LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK., Si X, Zang R, Zhang E, Liu Y, Shi X, Zhang E, Shao L, Li A, Yang N, Han X, Pan B, Zhang Z, Sun L, Sun Y., 2016
- ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells., Si X, Liu Y, Lv J, Ding H, Zhang XA, Shao L, Yang N, Cheng H, Sun L, Zhu D, Yang Y, Li A, Han X, Sun Y., 2016
- SATB1 Mediates Long-Range Chromatin Interactions: A Dual Regulator of Anti-Apoptotic BCL2 and Pro-Apoptotic NOXA Genes., Yang Y, Wang Z, Sun L, Shao L, Yang N, Yu D, Zhang X, Han X, Sun Y., 2015
Awards
- 2008: Jiangsu Province Science and Technology Progress Second Prize
- 2013: Jiangsu Province Education and Technology System 'May 1st' Women's Model
