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Xiaojun Chen
chenxiaojun@njmu.edu.cn
Chinese, English
Jiangsu
Nanjing Medical University
Basic Medical Sciences
  • 2008-2014 Doctor of Medicine: Nanjing Medical University
  • 2004-2008 Bachelor of Science in Pharmacy: Nanjing Medical University
  • Outstanding Young and Middle-aged Academic Leader at Nanjing Medical University
  • Excellent Young Backbone Teacher in Jiangsu Province's 'Qinglan Project'
  • 2018-present - Nanjing Medical University - Associate Professor in the Department of Pathogen Biology
  • 2014-2018 - Nanjing Medical University - Lecturer in the Department of Pathogen Biology
  • Third Prize in the National College Medical Comprehensive Experimental Teaching Program Creative Competition for 'Virtual and Real Combination, Discipline Integration' Schistosomiasis Comprehensive Experiment (2023)
  • Bronze Award in the National College Student Basic Medical Innovation Research and Experimental Design Forum, as a Mentor (2023)
  • First Prize in the Eastern Division of the National College Student Basic Medical Innovation Research and Experimental Design Forum, as a Mentor (2023)
  • Excellent Young Backbone Teacher in Jiangsu Province's 'Qinglan Project' (2022)
  • Discipline (Academic) Leader in the 'Excellent Young and Middle-aged Teacher Support Program' at Nanjing Medical University (2022)
  • Excellent Graduate Mentor Team at Nanjing Medical University (2022)
  • Hengrui Teaching Team Award, Morphological Experimental Science Team, School of Basic Medicine (2020)
  • Silver Award in the 11th 'Challenge Cup' National College Student Entrepreneurship Competition, as a Mentor (2018)
  • Gold Award in the 'Create Youth' Jiangsu Province College Student Entrepreneurship Competition, as a Mentor (2018)
  • Young Backbone Teacher in the 'Excellent Young and Middle-aged Teacher Support Program' at Nanjing Medical University (2017)
Mechanisms of host perception of pathogen infection and stress response
  • TGF-beta1 induces PD-1 expression in macrophages through SMAD3-STAT3 cooperative signaling in chronic inflammation., Zhigang Lei, Rui Tang, Yu Wu, Chenxu Mao, Weijie Xue, Junyao Shen, Jiaojiao Yu, Xiaohong Wang, Xin Qi, Chuan Wei, Lei Xu, Jifeng Zhu, Yalin Li, Xiujun Zhang, Chunyan Ye, Xiaojun Chen, Xiaojun Yang, Sha Zhou, Chuan Su, 2024
  • CD1d protects against hepatocyte apoptosis in non-alcoholic steatohepatitis., Zhigang Lei, Jiaojiao Yu, Yu Wu, Junyao Shen, Shibo Lin, Weijie Xue, Chenxu Mao, Rui Tang, Haoran Sun, Xin Qi, Xiaohong Wang, Lei Xu, Chuan Wei, Xiaowei Wang, Hongbing Chen, Ping Hao, Wen Yin, Jifeng Zhu, Yalin Li, Yi Wu, Shouguo Liu, Hui Liang, Xiaojun Chen, Chuan Su, Sha Zhou, 2024
  • IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection., Lei Xu, Chuan Wei, Ying Chen, Yue Wu, Xiaoli Shou, Wenjie Chen, Di Lu, Haoran Sun, Wei Li, Beibei Yu, Xiaowei Wang, Xiaojun Zhang, Yanxiong Yu, Zhigang Lei, Rui Tang, Jifeng Zhu, Yalin Li, Linrong Lu, Hong Zhou, Sha Zhou, Chuan Su, Xiaojun Chen, 2022
  • Schistosome infection promotes osteoclast-mediated bone loss., Wei Li, Chuan Wei, Lei Xu, Beibei Yu, Ying Chen, Di Lu, Lina Zhang, Xian Song, Liyang Dong, Sha Zhou, Zhipeng Xu, Jifeng Zhu, Xiaojun Chen, Chuan Su, 2021
  • Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection., Zhipeng Xu, Lei Xu, Wei Li, Xin Jin, Xian Song, Xiaojun Chen, Jifeng Zhu, Sha Zhou, Yong Li, Weiwei Zhang, Xiaoxiao Dong, Xiaowei Yang, Feng Liu, Hui Bai, Qi Chen, Chuan Su, 2017
  • Follicular helper T cells promote liver pathology in mice during Schistosoma japonicum infection., Xiaojun Chen, Xiaowei Yang, Yong Li, Jifeng Zhu, Sha Zhou, Zhipeng Xu, Lei He, Xue Xue, Weiwei Zhang, Xiaoxiao Dong, Henry Wu, Carrie J Li, Hsiang-Ting Hsu, Wenjun Kong, Feng Liu, Prem B. Tripathi, Michelle S. Yu, Jason Chang, Liang Zhou, Chuan Su, 2014
  • Novel insight from the first lung transplant of a COVID-19 patient., Xiaojun Chen, Kai Li, Lei Xu, Youjia Yu, Bo Wu, Yuanlin He, Wene Zhao, Ding Li, Changxing Luan, Li Hu, Jie Wang, Jingjing Ding, Yanfang Yu, JingXin Li, Zhongming Tan, Xiaofei Liu, Dong Wei, Zhihong Zhang, Xuejiang Guo, Chuan Su, Zhibin Hu, Yueshuai Guo, Jingyu Chen, Feng Chen, 2021
  • Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection., Xiaojun Chen, Zhipeng Xu, Chuan Wei, Xiaowei Yang, Lei Xu, Sha Zhou, Jifeng Zhu, Chuan Su, 2020
  • hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected mice., Liyang Dong, Yanan Pu, Xiaojun Chen, Xin Qi, Lina Zhang, Lei Xu, Wei Li, Yongbin Ma, Sha Zhou, Jifeng Zhu, Yalin Li, Xuefeng Wang, Chuan Su, 2020
  • CD40 Signaling Promotes CXCR5 Expression in B Cells via Noncanonical NF-κB Pathway Activation., Chuan Wei, Ying Chen, Lei Xu, Beibei Yu, Di Lu, Yanxiong Yu, Zhigang Lei, Rui Tang, Sha Zhou, Jifeng Zhu, Xiaojun Chen, and Chuan Su, 2020
  • The regulation of regulation: interleukin-10 increases CD4(+) CD25(+) regulatory T cells but impairs their immunosuppressive activity in murine models with schistosomiasis japonica or asthma., Lei He, Sha Zhou, Qianqian Qi, Ying Chi, Jifeng Zhu, Zhipeng Xu, Xuefeng Wang, Hoellwarth J, Feng Liu, Xiaojun Chen, Chuan Su, 2018
  • Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410., Liyang Dong, Yanan Pu, Qianqian Qi, Lei Xu, Lina Zhang, Wei Li, Chuan Wei, Xiaofan Wang, Sha Zhou, Jifeng Zhu, Xuefeng Wang, Feng Liu, Xiaojun Chen, Chuan Su, 2018
  • The IL-33-ST2-MyD88 axis promotes regulatory T cell proliferation in the murine liver., Lei Xu, Wei Li, Xiaofan Wang, Lina Zhang, Qianqian Qi, Liyang Dong, Chuan Wei, Yanan Pu, Yalin Li, Jifeng Zhu, Sha Zhou, Feng Liu, Xiaojun Chen, Chuan Su, 2018
  • SjHSP60 induces CD4(+) CD25(+) Foxp3(+) Tregs via TLR4-Mal-drived production of TGF-beta in macrophages., Sha Zhou, Qianqian Qi, Xiaofan Wang, Lina Zhang, Lei Xu, Liyang Dong, Jifeng Zhu, Yalin Li, Xuefeng Wang, Zhipeng Xu, Feng Liu, Wei Hu, Liang Zhou, Xiaojun Chen, Chuan Su, 2018
  • Distribution of Peripheral Memory T Follicular Helper Cells in Patients with Schistosomiasis Japonica., Xiaojun Chen, Wei Li, Yang Zhang, Xian Song, Lei Xu, Zhipeng Xu, Sha Zhou, Jifeng Zhu, Xin Jin, Feng Liu, Gengxin Chen, Chuan Su, 2015
Host Perception Pathogen Infection Stress Response Immune Regulation Hepatocytes Macrophages Cd4+ T Cells Central Immune Organs Thymus Immune Pathology

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