Professor | Rui He | Asia Growth Partners

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Name	Rui He
Contact Information	ruihe@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Rui He

Contact Information

ruihe@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1994.09—1999.09 Clinical Medicine, Bachelor's Degree: Sichuan University (West China University of Medical Sciences) 1999.09—2004.07 Internal Medicine, Doctoral Degree: Peking Union Medical College
Work Experience	2004.09—2009.10 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow in Immunology 2009.10—2012.11 - Fudan University, School of Basic Medical Sciences - Associate Professor 2012.12—Present - Fudan University, School of Basic Medical Sciences - Professor
Awards	2019: Shanghai Outstanding Academic Leader, Shanghai Science and Technology Commission 2013: National Natural Science Foundation Excellent Young Scientists Fund, National Natural Science Foundation of China 2013: Shanghai Shuguang Scholar, Shanghai Municipal Education Commission 2011: Shanghai Pujiang Talent, Shanghai Science and Technology Commission 2009: New Century Talent, Ministry of Education

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1994.09—1999.09 Clinical Medicine, Bachelor's Degree: Sichuan University (West China University of Medical Sciences)
1999.09—2004.07 Internal Medicine, Doctoral Degree: Peking Union Medical College

Work Experience

2004.09—2009.10 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow in Immunology
2009.10—2012.11 - Fudan University, School of Basic Medical Sciences - Associate Professor
2012.12—Present - Fudan University, School of Basic Medical Sciences - Professor

Awards

2019: Shanghai Outstanding Academic Leader, Shanghai Science and Technology Commission
2013: National Natural Science Foundation Excellent Young Scientists Fund, National Natural Science Foundation of China
2013: Shanghai Shuguang Scholar, Shanghai Municipal Education Commission
2011: Shanghai Pujiang Talent, Shanghai Science and Technology Commission
2009: New Century Talent, Ministry of Education

Areas of Focus	Regulation of Type 2 Immune Responses in Tissue and Disease Mechanisms of Immune Suppression in the Tumor Microenvironment
Publications	CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase, Lin Y, Cai Q, Chen Y, Shi T, Liu W, Mao L, Deng B, Ying Z, Gao Y, Luo H, Yang X, Huang X, Shi Y, He R, 2022 The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit, Lin Y, Xiao L, Cai Q, Zhu C, Li S, Li B, Liu T, Zhang Q, Wang Y, Li Y, He X, Pan D, Tang Q, Wu X, Pan W, Wang J, Li X, He R, 2021 CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation, Yin W, Li Y, Song Y, Zhang J, Wu C, Chen Y, Miao Y, Lin C, Lin Y, Yan D, Chen J, He R, 2021 The role of the LTB4-BLT1 axis in health and disease, He R, Chen Y, Cai Q, 2020 Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis, Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R, 2019 BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL-33 production, Xiong Y, Cui X, Li W, Lv J, Du L, Mi W, Li H, Chen Z, Leng Q, Zhou H, He R, 2019 IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma, Lv J, Xiong Y, Wen L, Cui X, Cheng X, Leng Q, He R, 2018 Chemerin plays a protective role in hepatocellular carcinoma by inhibiting the expression of GM-CSF and IL-6 and MDSC accumulation, Lin Y, Yang X, Liu W, Li B, Yin W, Shi Y, He R, 2017 FAP promotes immunosuppression by cancer-associated fibroblasts in the tumor microenvironment via STAT3-CCL2 signaling, Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R, 2016 BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury, Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y, He R, 2012

Areas of Focus

Regulation of Type 2 Immune Responses in Tissue and Disease
Mechanisms of Immune Suppression in the Tumor Microenvironment

Publications

CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase, Lin Y, Cai Q, Chen Y, Shi T, Liu W, Mao L, Deng B, Ying Z, Gao Y, Luo H, Yang X, Huang X, Shi Y, He R, 2022
The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit, Lin Y, Xiao L, Cai Q, Zhu C, Li S, Li B, Liu T, Zhang Q, Wang Y, Li Y, He X, Pan D, Tang Q, Wu X, Pan W, Wang J, Li X, He R, 2021
CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation, Yin W, Li Y, Song Y, Zhang J, Wu C, Chen Y, Miao Y, Lin C, Lin Y, Yan D, Chen J, He R, 2021
The role of the LTB4-BLT1 axis in health and disease, He R, Chen Y, Cai Q, 2020
Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis, Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R, 2019
BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL-33 production, Xiong Y, Cui X, Li W, Lv J, Du L, Mi W, Li H, Chen Z, Leng Q, Zhou H, He R, 2019
IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma, Lv J, Xiong Y, Wen L, Cui X, Cheng X, Leng Q, He R, 2018
Chemerin plays a protective role in hepatocellular carcinoma by inhibiting the expression of GM-CSF and IL-6 and MDSC accumulation, Lin Y, Yang X, Liu W, Li B, Yin W, Shi Y, He R, 2017
FAP promotes immunosuppression by cancer-associated fibroblasts in the tumor microenvironment via STAT3-CCL2 signaling, Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R, 2016
BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury, Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y, He R, 2012

Type 2 Immune Responses Tissue Immunity Disease Mechanisms Immune Regulation Tumor Microenvironment Immune Suppression Cancer Fibroblasts Macrophages Inflammation

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