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Rui He
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Type 2 Immune Responses
Tissue Immunity
Disease Mechanisms
Immune Regulation
Tumor Microenvironment
Immune Suppression
Cancer
Fibroblasts
Macrophages
Inflammation
Areas of Focus
- Regulation of Type 2 Immune Responses in Tissue and Disease
- Mechanisms of Immune Suppression in the Tumor Microenvironment
Work Experience
- 2004.09—2009.10 - Harvard Medical School, Boston Children's Hospital - Postdoctoral Fellow in Immunology
- 2009.10—2012.11 - Fudan University, School of Basic Medical Sciences - Associate Professor
- 2012.12—Present - Fudan University, School of Basic Medical Sciences - Professor
Academic Background & Achievements
- 1994.09—1999.09 Clinical Medicine, Bachelor's Degree: Sichuan University (West China University of Medical Sciences)
- 1999.09—2004.07 Internal Medicine, Doctoral Degree: Peking Union Medical College
Publications
- CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase, Lin Y, Cai Q, Chen Y, Shi T, Liu W, Mao L, Deng B, Ying Z, Gao Y, Luo H, Yang X, Huang X, Shi Y, He R, 2022
- The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit, Lin Y, Xiao L, Cai Q, Zhu C, Li S, Li B, Liu T, Zhang Q, Wang Y, Li Y, He X, Pan D, Tang Q, Wu X, Pan W, Wang J, Li X, He R, 2021
- CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation, Yin W, Li Y, Song Y, Zhang J, Wu C, Chen Y, Miao Y, Lin C, Lin Y, Yan D, Chen J, He R, 2021
- The role of the LTB4-BLT1 axis in health and disease, He R, Chen Y, Cai Q, 2020
- Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis, Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R, 2019
- BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL-33 production, Xiong Y, Cui X, Li W, Lv J, Du L, Mi W, Li H, Chen Z, Leng Q, Zhou H, He R, 2019
- IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma, Lv J, Xiong Y, Wen L, Cui X, Cheng X, Leng Q, He R, 2018
- Chemerin plays a protective role in hepatocellular carcinoma by inhibiting the expression of GM-CSF and IL-6 and MDSC accumulation, Lin Y, Yang X, Liu W, Li B, Yin W, Shi Y, He R, 2017
- FAP promotes immunosuppression by cancer-associated fibroblasts in the tumor microenvironment via STAT3-CCL2 signaling, Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R, 2016
- BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury, Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y, He R, 2012
Awards
- 2019: Shanghai Outstanding Academic Leader, Shanghai Science and Technology Commission
- 2013: National Natural Science Foundation Excellent Young Scientists Fund, National Natural Science Foundation of China
- 2013: Shanghai Shuguang Scholar, Shanghai Municipal Education Commission
- 2011: Shanghai Pujiang Talent, Shanghai Science and Technology Commission
- 2009: New Century Talent, Ministry of Education
