Professor | 何睿 | 数字化转型顾问

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Name	何睿
Contact Information	ruihe@fudan.edu.cn
Language ability	中文, 英语
Province	上海

Upload Avatar (500 x 500)

Name

何睿

Contact Information

ruihe@fudan.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	1994.09—1999.09 临床医学本科：四川大学（华西医科大学） 1999.09—2004.07 内科学博士研究生：中国协和医科大学
Work Experience	2004.09—2009.10 - 哈佛医学院波士顿儿童医院 - 免疫学博士后 2009.10—2012.11 - 复旦大学基础医学院 - 副教授 2012.12—至今 - 复旦大学基础医学院 - 教授
Awards	2019：上海市优秀学术带头人，上海市科委 2013：国家自然科学基金优青项目，国家自然科学基金委 2013：上海市曙光学者，上海市教委 2011：上海市浦江人才，上海市科委 2009：教育部新世纪人才，教育部

University/Lab Affiliation and Title

复旦大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

1994.09—1999.09 临床医学本科：四川大学（华西医科大学）
1999.09—2004.07 内科学博士研究生：中国协和医科大学

Work Experience

2004.09—2009.10 - 哈佛医学院波士顿儿童医院 - 免疫学博士后
2009.10—2012.11 - 复旦大学基础医学院 - 副教授
2012.12—至今 - 复旦大学基础医学院 - 教授

Awards

2019：上海市优秀学术带头人，上海市科委
2013：国家自然科学基金优青项目，国家自然科学基金委
2013：上海市曙光学者，上海市教委
2011：上海市浦江人才，上海市科委
2009：教育部新世纪人才，教育部

Areas of Focus	组织区域二型免疫应答的调控与疾病肿瘤微环境免疫抑制的调控机制
Publications	CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase, Lin Y, Cai Q, Chen Y, Shi T, Liu W, Mao L, Deng B, Ying Z, Gao Y, Luo H, Yang X, Huang X, Shi Y, He R, 2022 The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit, Lin Y, Xiao L, Cai Q, Zhu C, Li S, Li B, Liu T, Zhang Q, Wang Y, Li Y, He X, Pan D, Tang Q, Wu X, Pan W, Wang J, Li X, He R, 2021 CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation, Yin W, Li Y, Song Y, Zhang J, Wu C, Chen Y, Miao Y, Lin C, Lin Y, Yan D, Chen J, He R, 2021 The role of the LTB4-BLT1 axis in health and disease, He R, Chen Y, Cai Q, 2020 Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis, Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R, 2019 BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL-33 production, Xiong Y, Cui X, Li W, Lv J, Du L, Mi W, Li H, Chen Z, Leng Q, Zhou H, He R, 2019 IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma, Lv J, Xiong Y, Wen L, Cui X, Cheng X, Leng Q, He R, 2018 Chemerin plays a protective role in hepatocellular carcinoma by inhibiting the expression of GM-CSF and IL-6 and MDSC accumulation, Lin Y, Yang X, Liu W, Li B, Yin W, Shi Y, He R, 2017 FAP promotes immunosuppression by cancer-associated fibroblasts in the tumor microenvironment via STAT3-CCL2 signaling, Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R, 2016 BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury, Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y, He R, 2012

Areas of Focus

组织区域二型免疫应答的调控与疾病
肿瘤微环境免疫抑制的调控机制

Publications

CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase, Lin Y, Cai Q, Chen Y, Shi T, Liu W, Mao L, Deng B, Ying Z, Gao Y, Luo H, Yang X, Huang X, Shi Y, He R, 2022
The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit, Lin Y, Xiao L, Cai Q, Zhu C, Li S, Li B, Liu T, Zhang Q, Wang Y, Li Y, He X, Pan D, Tang Q, Wu X, Pan W, Wang J, Li X, He R, 2021
CCRL2 promotes antitumor T-cell immunity via amplifying TLR4-mediated immunostimulatory macrophage activation, Yin W, Li Y, Song Y, Zhang J, Wu C, Chen Y, Miao Y, Lin C, Lin Y, Yan D, Chen J, He R, 2021
The role of the LTB4-BLT1 axis in health and disease, He R, Chen Y, Cai Q, 2020
Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis, Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, Zhang Y, Jia L, Jiang Z, He R, 2019
BLT1 signaling in epithelial cells mediates allergic sensitization via promotion of IL-33 production, Xiong Y, Cui X, Li W, Lv J, Du L, Mi W, Li H, Chen Z, Leng Q, Zhou H, He R, 2019
IL-37 inhibits IL-4/IL-13-induced CCL11 production and lung eosinophilia in murine allergic asthma, Lv J, Xiong Y, Wen L, Cui X, Cheng X, Leng Q, He R, 2018
Chemerin plays a protective role in hepatocellular carcinoma by inhibiting the expression of GM-CSF and IL-6 and MDSC accumulation, Lin Y, Yang X, Liu W, Li B, Yin W, Shi Y, He R, 2017
FAP promotes immunosuppression by cancer-associated fibroblasts in the tumor microenvironment via STAT3-CCL2 signaling, Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, Dang Y, Chu Y, Fan J, He R, 2016
BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury, Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y, He R, 2012

二型免疫应答组织免疫疾病机制免疫调控肿瘤微环境免疫抑制癌症成纤维细胞巨噬细胞炎症

李慧艳 - 复旦大学

陈晓军 - 南京医科大学

邱竞帆 - 南京医科大学

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