Professor | Jun Yao | Asia Growth Partners

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Name	Jun Yao
Contact Information	joelyao@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Jun Yao

Contact Information

joelyao@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1997-2001 Bachelor: Nanjing University of Technology, School of Materials Science and Engineering 2001-2004 Master: Nanjing University of Technology, School of Life Science and Pharmaceutical Engineering, Biochemical Engineering 2004-2008 Doctorate: Nanjing University of Technology, School of Life Science and Pharmaceutical Engineering, Biochemical Engineering Hosted 2 National Natural Science Foundation projects Published over 20 research papers as first or corresponding author Received 2 national invention patents
Work Experience	2008-2017 - Nanjing Medical University, School of Basic Medical Sciences, Department of Biotechnology - Lecturer 2018-present - Nanjing Medical University, School of Basic Medical Sciences, Department of Medical Genetics - Associate Professor
Awards	2017: Zhao Xibao Young Teacher Award, Nanjing Medical University 2020: Excellent Undergraduate Mentor, Nanjing Medical University

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1997-2001 Bachelor: Nanjing University of Technology, School of Materials Science and Engineering
2001-2004 Master: Nanjing University of Technology, School of Life Science and Pharmaceutical Engineering, Biochemical Engineering
2004-2008 Doctorate: Nanjing University of Technology, School of Life Science and Pharmaceutical Engineering, Biochemical Engineering
Hosted 2 National Natural Science Foundation projects
Published over 20 research papers as first or corresponding author
Received 2 national invention patents

Work Experience

2008-2017 - Nanjing Medical University, School of Basic Medical Sciences, Department of Biotechnology - Lecturer
2018-present - Nanjing Medical University, School of Basic Medical Sciences, Department of Medical Genetics - Associate Professor

Awards

2017: Zhao Xibao Young Teacher Award, Nanjing Medical University
2020: Excellent Undergraduate Mentor, Nanjing Medical University

Areas of Focus	Molecular pathogenesis of hereditary deafness Biomedical materials
Publications	Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via Sonic Hedgehog signaling., Hairong Shi, Hongshun Wang, Cheng Zhang, Yajie Lu, Jun Yao, Zhibin Chen, Guangqian Xing, Qinjun Wei, Xin Cao, 2022 Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells., Yajie Lu, Min Zhang, Qinjun Wei, Zhibin Chen, Guangqian Xing, Jun Yao, Xin Cao, 2021 OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia., Jun Yao, Huasha Zeng, Min Zhang, Qinjun Wei, Ying Wang, Haiyuan Yang, Yajie Lu, Rongfeng Li, Qiang Xiong, Lining Zhang, Zhibin Chen, Guangqian Xing, Xin Cao, Yifan Dai, 2019 Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity., Hongshun Wang, Changsong Lin, Jun Yao, Hairong Shi, Cui Zhang, Qinjun Wei, Yajie Lu, Zhibin Chen, Guangqian Xing, Xin Cao, 2019 Spatial and temporal expression patterns of Osbpl2a and Osbpl2b during zebrafish embryonic development., Chunyu Liu, Jun Yao, Qinjun Wei, Guangqian Xing, Xin Cao, 2016 GPRASP2, a novel causative gene mutated in an X-linked recessive syndromic hearing loss., Guangqian Xing, Jun Yao, Chunyu Liu, Qinjun Wei, Xuli Qian, Lingxin Wu, Yajie Lu, Xin Cao, 2017 Genetic analysis of CLDN14 in the Chinese population affected with non-syndromic hearing loss., Yajie Lu, Jun Yao, Qinjun Wei, Jin Xu, Guangqian Xing, Xin Cao, 2018 Identification of OSBPL2 as a novel causative gene of progressive nonsyndromic hearing loss by exome sequencing., Guangqian Xing, Jun Yao, Bin Wu, Tingting Liu, Qinjun Wei, Cheng Liu, Yajie Lu, Zhibin Chen, Heng Zheng, Xiaonan Yang, Xin Cao, 2015 Probing the effect of two heterozygous mutations in codon 723 of SLC26A4 on deafness phenotype based on molecular dynamics simulations., Jun Yao, Xuli Qian, Jingxiao Bao, Qinjun Wei, Yajie Lu, Heng Zheng, Guangqian Xing, Xin Cao, 2015 大鼠耳蜗前体细胞的体外培养与分化鉴定., 姚俊, 王帅, 魏钦俊, 鲁雅洁, 邢光前, 曹新, 2015 FGF信号通路在内耳发育调控和毛细胞再生中的作用., 杨志, 姚俊, 曹新, 2018 胆甾醇基γ-聚谷氨酸载紫杉醇自组装纳米胶束的制备与性能., 胡凡, 肖港, 王育川, 姚俊, 曹新, 2018 胆甾醇基γ-聚谷氨酸负载阿霉素纳米胶束的制备与体内外释药性能评价., 姚俊, 肖港, 徐宁, 曹新, 徐虹, 2017 γ-聚谷氨酸胆甾醇基衍生物自组装纳米胶束的制备与表征., 李睿, 阮文辉, 姚俊, 陈宽婷, 魏钦俊, 鲁雅洁, 曹新, 2014

Areas of Focus

Molecular pathogenesis of hereditary deafness
Biomedical materials

Publications

Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via Sonic Hedgehog signaling., Hairong Shi, Hongshun Wang, Cheng Zhang, Yajie Lu, Jun Yao, Zhibin Chen, Guangqian Xing, Qinjun Wei, Xin Cao, 2022
Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells., Yajie Lu, Min Zhang, Qinjun Wei, Zhibin Chen, Guangqian Xing, Jun Yao, Xin Cao, 2021
OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia., Jun Yao, Huasha Zeng, Min Zhang, Qinjun Wei, Ying Wang, Haiyuan Yang, Yajie Lu, Rongfeng Li, Qiang Xiong, Lining Zhang, Zhibin Chen, Guangqian Xing, Xin Cao, Yifan Dai, 2019
Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity., Hongshun Wang, Changsong Lin, Jun Yao, Hairong Shi, Cui Zhang, Qinjun Wei, Yajie Lu, Zhibin Chen, Guangqian Xing, Xin Cao, 2019
Spatial and temporal expression patterns of Osbpl2a and Osbpl2b during zebrafish embryonic development., Chunyu Liu, Jun Yao, Qinjun Wei, Guangqian Xing, Xin Cao, 2016
GPRASP2, a novel causative gene mutated in an X-linked recessive syndromic hearing loss., Guangqian Xing, Jun Yao, Chunyu Liu, Qinjun Wei, Xuli Qian, Lingxin Wu, Yajie Lu, Xin Cao, 2017
Genetic analysis of CLDN14 in the Chinese population affected with non-syndromic hearing loss., Yajie Lu, Jun Yao, Qinjun Wei, Jin Xu, Guangqian Xing, Xin Cao, 2018
Identification of OSBPL2 as a novel causative gene of progressive nonsyndromic hearing loss by exome sequencing., Guangqian Xing, Jun Yao, Bin Wu, Tingting Liu, Qinjun Wei, Cheng Liu, Yajie Lu, Zhibin Chen, Heng Zheng, Xiaonan Yang, Xin Cao, 2015
Probing the effect of two heterozygous mutations in codon 723 of SLC26A4 on deafness phenotype based on molecular dynamics simulations., Jun Yao, Xuli Qian, Jingxiao Bao, Qinjun Wei, Yajie Lu, Heng Zheng, Guangqian Xing, Xin Cao, 2015
大鼠耳蜗前体细胞的体外培养与分化鉴定., 姚俊, 王帅, 魏钦俊, 鲁雅洁, 邢光前, 曹新, 2015
FGF信号通路在内耳发育调控和毛细胞再生中的作用., 杨志, 姚俊, 曹新, 2018
胆甾醇基γ-聚谷氨酸载紫杉醇自组装纳米胶束的制备与性能., 胡凡, 肖港, 王育川, 姚俊, 曹新, 2018
胆甾醇基γ-聚谷氨酸负载阿霉素纳米胶束的制备与体内外释药性能评价., 姚俊, 肖港, 徐宁, 曹新, 徐虹, 2017
γ-聚谷氨酸胆甾醇基衍生物自组装纳米胶束的制备与表征., 李睿, 阮文辉, 姚俊, 陈宽婷, 魏钦俊, 鲁雅洁, 曹新, 2014

Hereditary Deafness Molecular Pathogenesis Genetic Mutations Auditory Cells Biomedical Materials Nanoparticles Drug Delivery Gene Therapy Cell Signaling Hearing Loss

Huang Bo - Peking Union Medical College

Zhiqiang Lin - Peking University

Can Guo - Central South University

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