Professor | 姚俊 | 数字化转型顾问

	Upload Avatar (500 x 500)
Name	姚俊
Contact Information	joelyao@njmu.edu.cn
Language ability	中文, 英语
Province	江苏

Upload Avatar (500 x 500)

Name

姚俊

Contact Information

joelyao@njmu.edu.cn

Language ability

中文, 英语

Province

江苏

University/Lab Affiliation and Title	南京医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	1997-2001 学士：南京工业大学，材料科学与工程学院 2001-2004 硕士：南京工业大学，生命科学与制药学院，生物化工专业 2004-2008 博士：南京工业大学，生命科学与制药学院，生物化工专业主持国家自然科学基金项目2项以第一或通讯作者发表科研论文20余篇获国家发明专利授权2项
Work Experience	2008-2017 - 南京医科大学，基础医学院生物技术系 - 讲师 2018-至今 - 南京医科大学，基础医学院医学遗传系 - 副教授
Awards	2017年：南京医科大学赵息保青年教师奖教金 2020年：南京医科大学优秀本科生导师

University/Lab Affiliation and Title

南京医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

1997-2001 学士：南京工业大学，材料科学与工程学院
2001-2004 硕士：南京工业大学，生命科学与制药学院，生物化工专业
2004-2008 博士：南京工业大学，生命科学与制药学院，生物化工专业
主持国家自然科学基金项目2项
以第一或通讯作者发表科研论文20余篇
获国家发明专利授权2项

Work Experience

2008-2017 - 南京医科大学，基础医学院生物技术系 - 讲师
2018-至今 - 南京医科大学，基础医学院医学遗传系 - 副教授

Awards

2017年：南京医科大学赵息保青年教师奖教金
2020年：南京医科大学优秀本科生导师

Areas of Focus	遗传性耳聋的分子发病机制生物医用材料
Publications	Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via Sonic Hedgehog signaling., Hairong Shi, Hongshun Wang, Cheng Zhang, Yajie Lu, Jun Yao, Zhibin Chen, Guangqian Xing, Qinjun Wei, Xin Cao, 2022 Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells., Yajie Lu, Min Zhang, Qinjun Wei, Zhibin Chen, Guangqian Xing, Jun Yao, Xin Cao, 2021 OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia., Jun Yao, Huasha Zeng, Min Zhang, Qinjun Wei, Ying Wang, Haiyuan Yang, Yajie Lu, Rongfeng Li, Qiang Xiong, Lining Zhang, Zhibin Chen, Guangqian Xing, Xin Cao, Yifan Dai, 2019 Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity., Hongshun Wang, Changsong Lin, Jun Yao, Hairong Shi, Cui Zhang, Qinjun Wei, Yajie Lu, Zhibin Chen, Guangqian Xing, Xin Cao, 2019 Spatial and temporal expression patterns of Osbpl2a and Osbpl2b during zebrafish embryonic development., Chunyu Liu, Jun Yao, Qinjun Wei, Guangqian Xing, Xin Cao, 2016 GPRASP2, a novel causative gene mutated in an X-linked recessive syndromic hearing loss., Guangqian Xing, Jun Yao, Chunyu Liu, Qinjun Wei, Xuli Qian, Lingxin Wu, Yajie Lu, Xin Cao, 2017 Genetic analysis of CLDN14 in the Chinese population affected with non-syndromic hearing loss., Yajie Lu, Jun Yao, Qinjun Wei, Jin Xu, Guangqian Xing, Xin Cao, 2018 Identification of OSBPL2 as a novel causative gene of progressive nonsyndromic hearing loss by exome sequencing., Guangqian Xing, Jun Yao, Bin Wu, Tingting Liu, Qinjun Wei, Cheng Liu, Yajie Lu, Zhibin Chen, Heng Zheng, Xiaonan Yang, Xin Cao, 2015 Probing the effect of two heterozygous mutations in codon 723 of SLC26A4 on deafness phenotype based on molecular dynamics simulations., Jun Yao, Xuli Qian, Jingxiao Bao, Qinjun Wei, Yajie Lu, Heng Zheng, Guangqian Xing, Xin Cao, 2015 大鼠耳蜗前体细胞的体外培养与分化鉴定., 姚俊, 王帅, 魏钦俊, 鲁雅洁, 邢光前, 曹新, 2015 FGF信号通路在内耳发育调控和毛细胞再生中的作用., 杨志, 姚俊, 曹新, 2018 胆甾醇基γ-聚谷氨酸载紫杉醇自组装纳米胶束的制备与性能., 胡凡, 肖港, 王育川, 姚俊, 曹新, 2018 胆甾醇基γ-聚谷氨酸负载阿霉素纳米胶束的制备与体内外释药性能评价., 姚俊, 肖港, 徐宁, 曹新, 徐虹, 2017 γ-聚谷氨酸胆甾醇基衍生物自组装纳米胶束的制备与表征., 李睿, 阮文辉, 姚俊, 陈宽婷, 魏钦俊, 鲁雅洁, 曹新, 2014

Areas of Focus

遗传性耳聋的分子发病机制
生物医用材料

Publications

Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via Sonic Hedgehog signaling., Hairong Shi, Hongshun Wang, Cheng Zhang, Yajie Lu, Jun Yao, Zhibin Chen, Guangqian Xing, Qinjun Wei, Xin Cao, 2022
Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells., Yajie Lu, Min Zhang, Qinjun Wei, Zhibin Chen, Guangqian Xing, Jun Yao, Xin Cao, 2021
OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia., Jun Yao, Huasha Zeng, Min Zhang, Qinjun Wei, Ying Wang, Haiyuan Yang, Yajie Lu, Rongfeng Li, Qiang Xiong, Lining Zhang, Zhibin Chen, Guangqian Xing, Xin Cao, Yifan Dai, 2019
Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity., Hongshun Wang, Changsong Lin, Jun Yao, Hairong Shi, Cui Zhang, Qinjun Wei, Yajie Lu, Zhibin Chen, Guangqian Xing, Xin Cao, 2019
Spatial and temporal expression patterns of Osbpl2a and Osbpl2b during zebrafish embryonic development., Chunyu Liu, Jun Yao, Qinjun Wei, Guangqian Xing, Xin Cao, 2016
GPRASP2, a novel causative gene mutated in an X-linked recessive syndromic hearing loss., Guangqian Xing, Jun Yao, Chunyu Liu, Qinjun Wei, Xuli Qian, Lingxin Wu, Yajie Lu, Xin Cao, 2017
Genetic analysis of CLDN14 in the Chinese population affected with non-syndromic hearing loss., Yajie Lu, Jun Yao, Qinjun Wei, Jin Xu, Guangqian Xing, Xin Cao, 2018
Identification of OSBPL2 as a novel causative gene of progressive nonsyndromic hearing loss by exome sequencing., Guangqian Xing, Jun Yao, Bin Wu, Tingting Liu, Qinjun Wei, Cheng Liu, Yajie Lu, Zhibin Chen, Heng Zheng, Xiaonan Yang, Xin Cao, 2015
Probing the effect of two heterozygous mutations in codon 723 of SLC26A4 on deafness phenotype based on molecular dynamics simulations., Jun Yao, Xuli Qian, Jingxiao Bao, Qinjun Wei, Yajie Lu, Heng Zheng, Guangqian Xing, Xin Cao, 2015
大鼠耳蜗前体细胞的体外培养与分化鉴定., 姚俊, 王帅, 魏钦俊, 鲁雅洁, 邢光前, 曹新, 2015
FGF信号通路在内耳发育调控和毛细胞再生中的作用., 杨志, 姚俊, 曹新, 2018
胆甾醇基γ-聚谷氨酸载紫杉醇自组装纳米胶束的制备与性能., 胡凡, 肖港, 王育川, 姚俊, 曹新, 2018
胆甾醇基γ-聚谷氨酸负载阿霉素纳米胶束的制备与体内外释药性能评价., 姚俊, 肖港, 徐宁, 曹新, 徐虹, 2017
γ-聚谷氨酸胆甾醇基衍生物自组装纳米胶束的制备与表征., 李睿, 阮文辉, 姚俊, 陈宽婷, 魏钦俊, 鲁雅洁, 曹新, 2014

遗传性耳聋分子发病机制基因突变听觉细胞生物医用材料纳米颗粒药物递送基因治疗细胞信号听力损失

曹新 - 南京医科大学

黄波 - 北京协和医学院

Area of Focus
免疫系统 | 抗体 | 细胞因子 | T细胞 | B细胞 | 自身免疫 | 炎症 | 疫苗 | 病原体 | 免疫反应 | 蛋白质 | 酶 | Dna | Rna | 细胞信号 | 代谢 | 基因组学 | 蛋白质组学 | 分子遗传学 | 生化途径 | 癌症 | 肿瘤 | 治疗 | 生物治疗 | 免疫治疗 | 细胞治疗 | 基因治疗 | 肿瘤学 | 临床试验 | 生物标志物

宫宁强 - 中国科学技术大学

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们