Professor | Mengfeng Li | Asia Growth Partners

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Name	Mengfeng Li
Contact Information	lmf@smu.edu.cn
Language ability	English, Chinese
Province	Guangdong

Upload Avatar (500 x 500)

Name

Mengfeng Li

Contact Information

lmf@smu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	Bachelor's and Doctorate in Clinical Medicine and Medical Virology: Sun Yat-sen University of Medical Sciences Postdoctoral training in the USA Published over 130 papers in international journals
Work Experience	2001-2005 - University of Pittsburgh School of Medicine - Assistant Professor 2005-present - Sun Yat-sen University - Professor
Awards	2020 Guangdong Provincial Natural Science Award First Prize: Research on the imbalance mechanism of signal network regulation in high-incidence malignant tumors and new diagnostic and treatment targets 2017 Ministry of Education Natural Science Award First Prize: Research on the imbalance mechanism of signal network regulation in tumor invasion and metastasis and new therapeutic targets

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Bachelor's and Doctorate in Clinical Medicine and Medical Virology: Sun Yat-sen University of Medical Sciences
Postdoctoral training in the USA
Published over 130 papers in international journals

Work Experience

2001-2005 - University of Pittsburgh School of Medicine - Assistant Professor
2005-present - Sun Yat-sen University - Professor

Awards

2020 Guangdong Provincial Natural Science Award First Prize: Research on the imbalance mechanism of signal network regulation in high-incidence malignant tumors and new diagnostic and treatment targets
2017 Ministry of Education Natural Science Award First Prize: Research on the imbalance mechanism of signal network regulation in tumor invasion and metastasis and new therapeutic targets

Areas of Focus	Molecular Oncology
Publications	Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells., Yan Sun, Xiaolin Lin, Bangdong Liu, Yaxuan Zhang, Wei Li, Sheng Zhang, Falian He, Han Tian, Xun Zhu, Ximeng Liu, Jueheng Wu, Junchao Cai, Mengfeng Li, 2021 Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter., Shanshan Wu #, Bangdong Liu #, Youhong Zhang, Ruohui Hong, Shihua Liu, Tao Xiang, Tianyu Tao, Junchao Cai, Jueheng Wu, Mengfeng Li, Hongyu Guan, 2021 Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling., Guan H, Zhu T, Wu S, Liu S, Liu B, Wu J, Cai J, Zhu X, Zhang X, Zeng M, Li J, Song E, Li M, 2019 Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus., Jie Yuan, Jianchen Yu, Yun Huang, Zhenjian He, Jia Luo, Yun Wu, Yingchun Zheng, Jueheng Wu, Xun Zhu, Haihe Wang, Mengfeng Li, 2020 EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression., Liu L, Yang Y, Liu S, Tao T, Cai J, Wu J, Guan H, Zhu X, He Z, Li J, Song E, Zeng M, Li M, 2019 CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy., Cai J, Li R, Xu X, Zhang L, Lian R, Fang L, Huang Y, Feng X, Liu X, Li X, Zhu X, Zhang H, Wu J, Zeng M, Song E, He Y, Yin Y, Li J, Li M, 2018 NLRP3 Inflammasome Activation Mediates Zika Virus-Associated Inflammation., He Z, Chen J, Zhu X, An S, Dong X, Yu J, Zhang S, Wu Y, Li G, Zhang Y, Wu J, Li M, 2018 Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC., Cai J, Fang L, Huang Y, Li R, Xu X, Hu Z, Zhang L, Yang Y, Zhu X, Zhang H, Wu J, Huang Y, Li J, Zeng M, Song E, He Y, Zhang L, Li M, 2017 CCT6A suppresses SMAD2 and promotes pro-metastatic TGF-β signaling., Ying Z, Tian H, Li Y, Lian R, Li W, Wu S, Zhang HZ, Wu J, Liu L, Song J, Guan H, Cai J, Zhu X, Li J, Li M, 2017 Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun to Promote Tumor Aggressiveness., Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, Song L, Li J, Li M, 2017 Dengue Virus Subverts Host Innate Immunity by Targeting Adaptor Protein MAVS., He Z, Zhu X, Wen W, Yuan J, Hu Y, Chen J, An S, Dong X, Lin C, Yu J, Wu J, Yang Y, Cai J, Li J, Li M, 2016 Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling., Fang L, Cai J, Chen B, Wu S, Li R, Xu X, Yang Y, Guan H, Zhu X, Zhang L, Yuan J, Wu J, Li M, 2016 Cellular microRNA-miR-548g-3p modulates the replication of dengue virus., Wen W, He Z, Jing Q, Hu Y, Lin C, Zhou R, Wang X, Su Y, Yuan J, Chen Z, Yuan J, Wu J, Li J, Zhu X, Li M, 2015

Areas of Focus

Molecular Oncology

Publications

Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells., Yan Sun, Xiaolin Lin, Bangdong Liu, Yaxuan Zhang, Wei Li, Sheng Zhang, Falian He, Han Tian, Xun Zhu, Ximeng Liu, Jueheng Wu, Junchao Cai*, Mengfeng Li*, 2021
Long non-coding RNA LEISA promotes progression of lung adenocarcinoma via enhancing interaction between STAT3 and IL-6 promoter., Shanshan Wu #, Bangdong Liu #, Youhong Zhang, Ruohui Hong, Shihua Liu, Tao Xiang, Tianyu Tao, Junchao Cai, Jueheng Wu*, Mengfeng Li*, Hongyu Guan*, 2021
Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling., Guan H, Zhu T, Wu S, Liu S, Liu B, Wu J, Cai J, Zhu X, Zhang X, Zeng M, Li J, Song E, Li M*, 2019
Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus., Jie Yuan, Jianchen Yu, Yun Huang, Zhenjian He, Jia Luo, Yun Wu, Yingchun Zheng, Jueheng Wu, Xun Zhu, Haihe Wang, Mengfeng Li*, 2020
EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression., Liu L, Yang Y, Liu S, Tao T, Cai J, Wu J, Guan H, Zhu X, He Z, Li J, Song E, Zeng M, Li M*, 2019
CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy., Cai J, Li R, Xu X, Zhang L, Lian R, Fang L, Huang Y, Feng X, Liu X, Li X, Zhu X, Zhang H, Wu J, Zeng M, Song E, He Y, Yin Y, Li J, Li M*, 2018
NLRP3 Inflammasome Activation Mediates Zika Virus-Associated Inflammation., He Z, Chen J, Zhu X, An S, Dong X, Yu J, Zhang S, Wu Y, Li G, Zhang Y, Wu J, Li M*, 2018
Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC., Cai J, Fang L, Huang Y, Li R, Xu X, Hu Z, Zhang L, Yang Y, Zhu X, Zhang H, Wu J, Huang Y, Li J, Zeng M, Song E, He Y, Zhang L, Li M*, 2017
CCT6A suppresses SMAD2 and promotes pro-metastatic TGF-β signaling., Ying Z, Tian H, Li Y, Lian R, Li W, Wu S, Zhang HZ, Wu J, Liu L, Song J, Guan H, Cai J, Zhu X, Li J, Li M*, 2017
Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun to Promote Tumor Aggressiveness., Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, Song L, Li J, Li M*, 2017
Dengue Virus Subverts Host Innate Immunity by Targeting Adaptor Protein MAVS., He Z, Zhu X, Wen W, Yuan J, Hu Y, Chen J, An S, Dong X, Lin C, Yu J, Wu J, Yang Y, Cai J, Li J, Li M*, 2016
Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling., Fang L, Cai J, Chen B, Wu S, Li R, Xu X, Yang Y, Guan H, Zhu X, Zhang L, Yuan J, Wu J, Li M*, 2016
Cellular microRNA-miR-548g-3p modulates the replication of dengue virus., Wen W, He Z, Jing Q, Hu Y, Lin C, Zhou R, Wang X, Su Y, Yuan J, Chen Z, Yuan J, Wu J, Li J, Zhu X, Li M*, 2015

Lung Cancer Uncontrolled Inflammation Signal Transduction Molecular Oncology Cancer Research Tumor Biology Oncogenes Cancer Therapy Biomarkers Clinical Translation

Genze Shao - Peking University

Yongguang Tao - Central South University

Ai-Ling Li - Fudan University

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