Professor | Xiao Yu | Asia Growth Partners

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Name	Xiao Yu
Contact Information	xiaoyu523@smu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Xiao Yu

Contact Information

xiaoyu523@smu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Awards	2023: Appointed as a young scholar in the national talent project by the Ministry of Education 2024: Received the 12th Chinese Society of Immunology Academic Award for Young Scholars 2019: Appointed as a 'Young Pearl River Scholar' in Guangdong Province

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Awards

2023: Appointed as a young scholar in the national talent project by the Ministry of Education
2024: Received the 12th Chinese Society of Immunology Academic Award for Young Scholars
2019: Appointed as a 'Young Pearl River Scholar' in Guangdong Province

Areas of Focus	Research on the correlation between the innate immune system recognition and regulation mechanisms and infectious diseases
Publications	The Toxoplasma Effector GRA4 Hijacks Host TBK1 to Oppositely Regulate Anti-T. Gondii Immunity and Tumor Immunotherapy, Hu Z., Zhang Y., Xie Y., Yang J., Tang H., Fan B., Zeng K., Han Z., Lu J., Jiang H., Peng W., Li H., Chen H., Wu S., Shen B., Lun Z.R., and Yu X., 2024 Dual nature of type I interferon responses and feedback regulations by SOCS1 dictate malaria mortality, Lu J., Hu Z., Jiang H., Wen Z., Li H., Li J., Zeng K., Xie Y., Chen H., Su X.Z., Cai C., and Yu X., 2024 Pristimerin suppresses AIM2 inflammasome by modulating AIM2-PYCARD/ASC stability via selective autophagy to alleviate tendinopathy, Jiang H., Xie Y., Lu J., Li H., Zeng K., Hu Z., Wu D., Yang J., Yao Z., Chen H., Gong X., and Yu X., 2024 VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation, Hu Z., Xie Y., Lu J., Yang J., Zhang J., Jiang H., Li H., Zhang Y., Wu D., Zeng K., Bai X., and Yu X., 2023 Natural killer cells: Warriors against malaria, Li H. and Yu X., 2023 Vangl2 suppresses NF-kB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation, Lu J., Zhang J., Jiang H., Hu Z., He L., Yang J., Xie Y., Wu D., Li H., Zeng K., Tan P., Xiao Q., Song Z., Bai X., and Yu X., 2023 SHIP1 modulates antimalarial immunity by bridging the crosstalk between type I IFN signaling and autophagy, Li H., Yang S., Zeng K., Guo J., Wu J., Jiang H., Xie Y., Lu J., Hu Z., Yang J., Su X., Cui J., and Yu X., 2023 Function and regulation of cGAS-STING signaling in infectious diseases, Du Y., Hu Z., Luo Y., Wang H.Y., Yu X., and Wang R.F., 2023 Activation of cGAS-STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b(+) Ly6C(hi) Proinflammatory Monocytes, Du Y., Luo Y., Hu Z., Lu J., Liu X., Xing C., Wu J., Duan T., Chu J., Wang H.Y., Su X.Z., Yu X., and Wang R.F., 2022 Inflammasome Activation Dampens Type I IFN Signaling to Strengthen Anti-Toxoplasma Immunity, Hu Z., Wu D., Lu J., Zhang Y., Yu S.M., Xie Y., Li H., Yang J., Lai D.H., Zeng K., Jiang H., Lun Z.R., and Yu X., 2022 Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65, Jiang H., Lin X., Liang W., Li Y., and Yu X., 2022 Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARgamma to inhibit NF-kappaB signalling pathway, Lu J., Guan H., Wu D., Hu Z., Zhang H., Jiang H., Yu J., Zeng K., Li H., Zhang H., Pan C., Cai D., and Yu X., 2021 Accelerator or Brake: Immune Regulators in Malaria, Cai C., Hu Z., and Yu X., 2020 A mathematic model to reveal delicate cross-regulation between MAVS/STING, inflammasome and MyD88-dependent type I interferon signalling, Cai C. and Yu X., 2020 Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity, Yu X., Du Y., Cai C., Cai B., Zhu M., Xing C., Tan P., Lin M., Wu J., Li J., Wang M., Wang H.Y., Su X.Z., and Wang R.F., 2018 A novel miR-200b-3p/p38IP pair regulates monocyte/macrophage differentiation, Yu X., Wang Q.L., Li Y.F., Wang X.D., Xu A., and Li Y., 2016 Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality, Yu X., Cai B., Wang M., Tan P., Ding X., Wu J., Li J., Li Q., Liu P., Xing C., Wang H.Y., Su X.Z., and Wang R.F., 2016

Areas of Focus

Research on the correlation between the innate immune system recognition and regulation mechanisms and infectious diseases

Publications

The Toxoplasma Effector GRA4 Hijacks Host TBK1 to Oppositely Regulate Anti-T. Gondii Immunity and Tumor Immunotherapy, Hu Z., Zhang Y., Xie Y., Yang J., Tang H., Fan B., Zeng K., Han Z., Lu J., Jiang H., Peng W., Li H., Chen H., Wu S., Shen B., Lun Z.R., and Yu X., 2024
Dual nature of type I interferon responses and feedback regulations by SOCS1 dictate malaria mortality, Lu J., Hu Z., Jiang H., Wen Z., Li H., Li J., Zeng K., Xie Y., Chen H., Su X.Z., Cai C., and Yu X., 2024
Pristimerin suppresses AIM2 inflammasome by modulating AIM2-PYCARD/ASC stability via selective autophagy to alleviate tendinopathy, Jiang H., Xie Y., Lu J., Li H., Zeng K., Hu Z., Wu D., Yang J., Yao Z., Chen H., Gong X., and Yu X., 2024
VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation, Hu Z., Xie Y., Lu J., Yang J., Zhang J., Jiang H., Li H., Zhang Y., Wu D., Zeng K., Bai X., and Yu X., 2023
Natural killer cells: Warriors against malaria, Li H. and Yu X., 2023
Vangl2 suppresses NF-kB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation, Lu J., Zhang J., Jiang H., Hu Z., He L., Yang J., Xie Y., Wu D., Li H., Zeng K., Tan P., Xiao Q., Song Z., Bai X., and Yu X., 2023
SHIP1 modulates antimalarial immunity by bridging the crosstalk between type I IFN signaling and autophagy, Li H., Yang S., Zeng K., Guo J., Wu J., Jiang H., Xie Y., Lu J., Hu Z., Yang J., Su X., Cui J., and Yu X., 2023
Function and regulation of cGAS-STING signaling in infectious diseases, Du Y., Hu Z., Luo Y., Wang H.Y., Yu X., and Wang R.F., 2023
Activation of cGAS-STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b(+) Ly6C(hi) Proinflammatory Monocytes, Du Y., Luo Y., Hu Z., Lu J., Liu X., Xing C., Wu J., Duan T., Chu J., Wang H.Y., Su X.Z., Yu X., and Wang R.F., 2022
Inflammasome Activation Dampens Type I IFN Signaling to Strengthen Anti-Toxoplasma Immunity, Hu Z., Wu D., Lu J., Zhang Y., Yu S.M., Xie Y., Li H., Yang J., Lai D.H., Zeng K., Jiang H., Lun Z.R., and Yu X., 2022
Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65, Jiang H., Lin X., Liang W., Li Y., and Yu X., 2022
Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARgamma to inhibit NF-kappaB signalling pathway, Lu J., Guan H., Wu D., Hu Z., Zhang H., Jiang H., Yu J., Zeng K., Li H., Zhang H., Pan C., Cai D., and Yu X., 2021
Accelerator or Brake: Immune Regulators in Malaria, Cai C., Hu Z., and Yu X., 2020
A mathematic model to reveal delicate cross-regulation between MAVS/STING, inflammasome and MyD88-dependent type I interferon signalling, Cai C. and Yu X., 2020
Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity, Yu X., Du Y., Cai C., Cai B., Zhu M., Xing C., Tan P., Lin M., Wu J., Li J., Wang M., Wang H.Y., Su X.Z., and Wang R.F., 2018
A novel miR-200b-3p/p38IP pair regulates monocyte/macrophage differentiation, Yu X., Wang Q.L., Li Y.F., Wang X.D., Xu A., and Li Y., 2016
Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality, Yu X., Cai B., Wang M., Tan P., Ding X., Wu J., Li J., Li Q., Liu P., Xing C., Wang H.Y., Su X.Z., and Wang R.F., 2016

Infection Immunity Innate Immunity Type I Interferon Inflammasome Regulation Mechanism Host Response Immune Homeostasis Therapeutic Targets

Baoyu Zhao - Fudan University

Dongqing Li - Wuhan University

Binbo Liu - Wuhan University

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