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Baoyu Zhao
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Innate Immunity
Host Response
Pathogen Virulence
Immune Evasion
Protein Structure
Agonists
Inhibitors
Molecular Mechanisms
Research
Development
Areas of Focus
- Molecular Mechanisms of Host Innate Immune Response
- Molecular Mechanisms of Pathogen Virulence and Immune Evasion
- Development of Agonists and Inhibitors Based on Protein Structure
Work Experience
- 2013.09---2018.08 - Texas A&M University - Postdoctoral Researcher
- 2018.09---2021.04 - Texas A&M University - Assistant Research Scientist
- 2022.02---Present - Fudan University, Basic Medical Sciences - Researcher
Academic Background & Achievements
- 2003.09---2007.07 Bachelor's Degree: Qufu Normal University, College of Life Sciences
- 2007.09---2013.07 Doctorate: Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences
Publications
- The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS, Baoyu Zhao, Pengbiao Xu, Chesley M. Rowlett, Tao Jing, Omkar Shinde, Yuanjiu Lei, A. Phillip West, Wenshe Ray Liu, Pingwei Li, 2020
- A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1, Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L. Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu, Fanxiu Zhu, Yang Liu, Arthur Laganowsky, Xueyun Zheng, Jun-Yuan Ji, A. Phillip West, Robert O. Watson, Pingwei Li, 2019
- Structure and function of the Zika virus full-length NS5 protein, Baoyu Zhao, Guanghui Yi, Fenglei Du, Yin-Chih Chuang, Robert C. Vaughan, Banumathi Sankaran, C. Cheng Kao, Pingwei Li, 2017
- Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins, Baoyu Zhao, Chang Shu, Xinsheng Gao, Banumathi Sankaran, Fenglei Du, Catherine L. Shelton, Andrew B. Herr, Jun-Yuan Ji, Pingwei Li, 2016
- Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation, Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug, 2015
Awards
- 2015: Fudan University, Zhuoxue Talent Program
