Professor | 赵宝玉 | 数字化转型顾问

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Name

赵宝玉

Contact Information

baoyuzhao@fudan.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003.09---2007.07 本科: 曲阜师范大学生命科学学院 2007.09---2013.07 博士: 中国科学院福建物质结构研究所
Work Experience	2013.09---2018.08 - 美国Texas A&M University - 博士后 2018.09---2021.04 - 美国Texas A&M University - 助理研究科学家 2022.02---至今 - 复旦大学基础医学院 - 研究员
Awards	2015: 复旦大学，卓学人才计划

University/Lab Affiliation and Title

复旦大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	宿主先天免疫应答的分子机制研究病原微生物致病以及免疫逃逸的分子机制研究基于蛋白质结构的激动剂和抑制剂的研发
Publications	The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS, 赵宝玉, 徐鹏彪, Chesley M. Rowlett, 景涛, Omkar Shinde, 雷元久, A. Phillip West, 刘文社, 李平伟, 2020 A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1, 赵宝玉, 杜凤雷, 徐鹏彪, 舒畅, Banumathi Sankaran, Samantha L. Bell, 刘梦梦, 雷元久, 高新生, 傅晓峰, 朱凡秀, 刘洋, Arthur Laganowsky, 郑雪云, 季君远, A. Phillip West, Robert O. Watson, 李平伟, 2019 Structure and function of the Zika virus full-length NS5 protein, 赵宝玉, 易光辉, 杜凤雷, Yin-Chih Chuang, Robert C. Vaughan, Banumathi Sankaran, C. Cheng Kao, 李平伟, 2017 Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins, 赵宝玉, 舒畅, 高新生, Banumathi Sankaran, 杜凤雷, Catherine L. Shelton, Andrew B. Herr, 季君远, 李平伟, 2016 Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation, 赵宝玉, Sonu Gandhi, 蔡元, 罗志普, 李瑞, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, 黄明东, Michael Ploug, 2015

Areas of Focus

宿主先天免疫应答的分子机制研究
病原微生物致病以及免疫逃逸的分子机制研究
基于蛋白质结构的激动剂和抑制剂的研发

Publications

The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS, 赵宝玉, 徐鹏彪, Chesley M. Rowlett, 景涛, Omkar Shinde, 雷元久, A. Phillip West, 刘文社, 李平伟, 2020
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1, 赵宝玉, 杜凤雷, 徐鹏彪, 舒畅, Banumathi Sankaran, Samantha L. Bell, 刘梦梦, 雷元久, 高新生, 傅晓峰, 朱凡秀, 刘洋, Arthur Laganowsky, 郑雪云, 季君远, A. Phillip West, Robert O. Watson, 李平伟, 2019
Structure and function of the Zika virus full-length NS5 protein, 赵宝玉, 易光辉, 杜凤雷, Yin-Chih Chuang, Robert C. Vaughan, Banumathi Sankaran, C. Cheng Kao, 李平伟, 2017
Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins, 赵宝玉, 舒畅, 高新生, Banumathi Sankaran, 杜凤雷, Catherine L. Shelton, Andrew B. Herr, 季君远, 李平伟, 2016
Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation, 赵宝玉, Sonu Gandhi, 蔡元, 罗志普, 李瑞, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, 黄明东, Michael Ploug, 2015

先天免疫宿主反应病原体毒力免疫逃逸蛋白质结构激动剂抑制剂分子机制研究开发

吕丹 - 北京大学

Area of Focus
免疫学 | 抗病毒 | 抗肿瘤 | 纳米医药 | 病毒 | 癌症 | 免疫逃逸 | 机制 | 研究 | 开发

刘云华 - 浙江大学

曾聪 - 复旦大学

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