Professor | 吕丹 | 数字化转型顾问

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Name	吕丹
Contact Information	taotao@bjmu.edu.cn
Language ability	中文, 英语
Province	北京

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Name

吕丹

Contact Information

taotao@bjmu.edu.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	北京大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2006年 - 中国医科大学临床医学本科 2011年 - 北京大学基础医学院免疫学系博士国家“优青”获得者
Work Experience	美国Oklahoma Medical Research Foundation 博士后北京大学博士后 2018年 - 加入北京大学系统生物医学研究所

University/Lab Affiliation and Title

北京大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2006年 - 中国医科大学临床医学本科
2011年 - 北京大学基础医学院免疫学系博士
国家“优青”获得者

Work Experience

美国Oklahoma Medical Research Foundation 博士后
北京大学博士后
2018年 - 加入北京大学系统生物医学研究所

Areas of Focus	抗病毒与抗肿瘤免疫
Publications	A gradient pH-sensitive polymer-based antiviral strategy via viroporin-induced membrane acidification, Sun Y, Gong L, Yin Y, Zhang L, Sun Q, Feng K, Cui Y, Zhang Q, Zhang X, Deng X, You F, Lu D, Lin Z, 2022 The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity, Dan Lu, Liu Liang, Sun Yizhe, Song Jia, Yin Qi, Zhang Guangze, Qi Fang, Hu Zixi, Yang Zeliang, Zhou Ze, Hu Ying, Zhang Lianhai, Ji Jiafu, Zhao Xuyang, Jin Yan, McNutt MA, Yin Yuxin, 2020 PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer, Sun Y, Lu D, Yin Y, Song J, Liu Y, Hao W, Qi F, Zhang G, Zhang X, Liu L, Lin Z, Liang H, Zhao X, Jin Y, Yin Y, 2021 The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity, Song J, Liu T, Yin Y, Zhao W, Lin Z, Yin Y, Lu D, You F, 2021 Manganese nanodepot augments host immune response against coronavirus, Sun Y, Yin Y, Gong L, Liang Z, Zhu C, Ren C, Zheng N, Zhang Q, Liu H, Liu W, You F, Lu D, Lin Z, 2020 Manganese-based multifunctional nanoplatform for dual-modal imaging and synergistic therapy of breast cancer, Zhu C, Ma Q, Gong L, Di S, Gong J, Wang Y, Xiao S, Zhang L, Zhang Q, Fu JJ, Lu D, Lin Z, 2022 Mutations of deubiquitinase OTUD1 are associated with autoimmune disorders, Lu D, Song J, Sun Y, Qi F, Liu L, Jin Y, McNutt MA, Yin Y, 2018 The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation, Lu D, Liu L, Ji X, Gao Y, Chen X, Liu Y, Liu Y, Zhao X, Li Y, Li Y, Jin Y, Zhang Y, McNutt MA, Yin Y, 2015 The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma, Lu D, Dong D, Zhou Y, Lu M, Pang XW, Li Y, Tian XJ, Zhang Y, Zhang J, 2013 Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma, Lu D, Zhao W, Dong D, Qian XP, Zhang Y, Tian XJ, Zhang J, 2011

Areas of Focus

抗病毒与抗肿瘤免疫

Publications

A gradient pH-sensitive polymer-based antiviral strategy via viroporin-induced membrane acidification, Sun Y, Gong L, Yin Y, Zhang L, Sun Q, Feng K, Cui Y, Zhang Q, Zhang X, Deng X, You F, Lu D, Lin Z, 2022
The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity, Dan Lu, Liu Liang, Sun Yizhe, Song Jia, Yin Qi, Zhang Guangze, Qi Fang, Hu Zixi, Yang Zeliang, Zhou Ze, Hu Ying, Zhang Lianhai, Ji Jiafu, Zhao Xuyang, Jin Yan, McNutt MA, Yin Yuxin, 2020
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer, Sun Y, Lu D, Yin Y, Song J, Liu Y, Hao W, Qi F, Zhang G, Zhang X, Liu L, Lin Z, Liang H, Zhao X, Jin Y, Yin Y, 2021
The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity, Song J, Liu T, Yin Y, Zhao W, Lin Z, Yin Y, Lu D, You F, 2021
Manganese nanodepot augments host immune response against coronavirus, Sun Y, Yin Y, Gong L, Liang Z, Zhu C, Ren C, Zheng N, Zhang Q, Liu H, Liu W, You F, Lu D, Lin Z, 2020
Manganese-based multifunctional nanoplatform for dual-modal imaging and synergistic therapy of breast cancer, Zhu C, Ma Q, Gong L, Di S, Gong J, Wang Y, Xiao S, Zhang L, Zhang Q, Fu JJ, Lu D, Lin Z, 2022
Mutations of deubiquitinase OTUD1 are associated with autoimmune disorders, Lu D, Song J, Sun Y, Qi F, Liu L, Jin Y, McNutt MA, Yin Y, 2018
The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation, Lu D, Liu L, Ji X, Gao Y, Chen X, Liu Y, Liu Y, Zhao X, Li Y, Li Y, Jin Y, Zhang Y, McNutt MA, Yin Y, 2015
The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma, Lu D, Dong D, Zhou Y, Lu M, Pang XW, Li Y, Tian XJ, Zhang Y, Zhang J, 2013
Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma, Lu D, Zhao W, Dong D, Qian XP, Zhang Y, Tian XJ, Zhang J, 2011

免疫学抗病毒抗肿瘤纳米医药病毒癌症免疫逃逸机制研究开发

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