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Bo Li
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Tumor Metabolism
Hypoxia Stress
Cancer Therapy
Molecular Medicine
Oncology
Cell Signaling
Biochemistry
Genomics
Proteomics
Immunotherapy
Areas of Focus
- Molecular Medicine
- Basic Cancer Research
Academic Background & Achievements
- Bachelor's Degree: Peking University, College of Chemistry and Molecular Engineering
- Doctorate: Cornell University, Department of Chemistry and Chemical Biology
- Postdoctoral Research: University of Pennsylvania, School of Medicine
- National Overseas High-Level Young Talent
- National Excellent Young Scientist Fund Recipient
- Guangdong Pearl River Talent Plan Innovation and Entrepreneurship Team Leader
- Guangdong Medical Leading Talent
Publications
- Extracellular vesicle-mediated communication between hepatocytes and natural killer cells promotes hepatocellular tumorigenesis., Liu Z, You Y, Chen Q, Li G, Pan W, Yang Q, Dong J, Wu Y, Bei JX, Pan C*, Li F*, Li B*, 2022
- MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma., Lu Y, Yang Q, Su Y, Ji Y, Li G, Yang X, Xu L, Lu Z, Dong J, Wu Y, Bei JX, Pan C, Gu X*, Li B*, 2021
- Amino acids and RagD potentiate mTORC1 activation in CD8 + T cells to confer antitumor immunity., Zhang Y, Hu H, Liu W, Yan SM, Li Y, Tan L, Chen Y, Liu J, Peng Z, Yuan Y, Huang W, Yu F, He X, Li B*, Zhang H*, 2021
- FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome., Li F, Huangyang P, Burrows M, Guo K, Riscal R, Godfrey J, Lee KE, Lin N, Lee P, Blair IA, Keith B, Li B*, Simon MC*, 2020
- A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-bisphosphatase Enables Hepatic and Renal Tumorigenesis., Liao K, Deng S, Xu L, Pan W, Yang S, Zheng F, Wu X, Hu H, Liu Z, Luo J, Zhang R, Kuang DM, Dong J, Wu Y, Zhang H, Zhou P, Bei JX, Xu Y, Ji Y, Wang P, Ju HQ, Xu RH, Li B*, 2020
- Fructose-1,6- bisphosphatase opposes renal carcinoma progression., Li B#, Qiu B, Lee DS, Walton ZE, Ochocki JD, Mathew LK, Mancuso A, Gade TP, Keith B, Nissim I, Simon MC*, 2014
- ATF4 Regulates MYC-mediated Neuroblastoma Cell Death upon Glutamine Deprivation., Qing G#, Li B#, Vu A, Skuli N, Walton ZE, Liu X, Mayes PA, Wise DR, Thompson CB, Maris JM, Hogarty MD, Simon MC*, 2012
- RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells., Li B#, Antonyak MA#, Zhang J, Cerione RA*, 2012
- Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells., Antonyak MA#, Li B#, Boroughs LK, Johnson JL, Bryant KL, Holowka DA, Cerione RA*, 2011
- EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation., Li B#, Antonyak MA#, Druso JE, Cheng L, Nikitin AY, Cerione RA, 2010
Awards
- National Overseas High-Level Young Talent
- National Excellent Young Scientist Fund Recipient
