Professor | Jinghua Liu | Asia Growth Partners

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Name	Jinghua Liu
Contact Information	liujhua@smu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Jinghua Liu

Contact Information

liujhua@smu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1999 - Medical Doctorate: Third Military Medical University Studied at University of Pittsburgh, USA Studied at National University of Ireland
Work Experience	Current - Southern Medical University - Deputy Director of the Department of Pathophysiology Over 20 years in teaching and research

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1999 - Medical Doctorate: Third Military Medical University
Studied at University of Pittsburgh, USA
Studied at National University of Ireland

Work Experience

Current - Southern Medical University - Deputy Director of the Department of Pathophysiology
Over 20 years in teaching and research

Areas of Focus	Cell signal transduction in inflammation Mechanisms of sepsis Innate immunity training
Publications	Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine, Na Peng, Yan Geng, Jiafu Ouyang, Shuai Liu, Fangfang Yuan, Yantong Wan, Wenda Chen, BaoJun Yu, Youqing Tang, Lei Su, Huaping Liang, Jiang Huai Wang and Jinghua Liu, 2023 Gene expression variability across cells and species shapes the relationship between renal resident macrophages and infiltrated macrophages, Xiangjun Ji, Junwei Cai, Lixin Liang, Tieliu Shi and Jinghua Liu, 2023 Bibliometric and Visual Analysis of Neutrophil Extracellular Traps from 2004 to 2022, Yantong Wan, Junyi Shen, Jiafu Ouyang, Peng Dong, Yinghao Hong, Lixin Liang, Jinghua Liu, 2022 Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect, Piao Luo, Qian Zhang, Tian‑Yu Zhong, Jia‑Yun Chen, Jun‑Zhe Zhang, Ya Tian, Liu‑Hai Zheng, Fan Yang, Ling‑Yun Dai, Chang Zou, Zhi‑Jie Li, Zhijie Li, Jinghua Liu, Ji‑Gang Wang, 2022 Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia, Hanhui Zhong, Haitao Lin, Qiongni Pang, Jinling Zhuang, Xiaolei Liu, Xiaolian Li, Jinghua Liu & Jing Tang, 2021 An early neutrophil recruitment into the infectious site is critical for BLP tolerance-afforded protection against microbial sepsis, Wenting Chen, Shuqi Zhao, Michael Ita, Yue Li, Jingjing Ji, Yong Jiang, H. Paul Redmond, Jiang Huai Wang, and Jinghua Liu, 2020 The novel methyltransferase SETD4 regulates TLR agonist-induced expression of cytokines through methylation of lysine 4 at histone 3 in macrophages, Yuyun Zhong, Ping Ye, Zhuzhong Mei, Sui Huang, Mengyi Huang, Li Yue, Shixian Niu, Shuqi Zhao, Junwei Cai, Juan Wang, Yong Jiang, Jinghua Liu, 2019 Rab20 is critical for bacterial lipoprotein tolerization-enhanced bactericidal activity in macrophages during bacterial infection, Shuqi Zhao, Dalin Xi, Junwei Cai, Wenting Chen, Jing Xiang, Na Peng, Juan Wang, Yong Jiang, Zhuzhong Mei and Jinghua Liu, 2019 Differences in LPS-induced inflammatory response between MEFs and BMDMs, Yue Li, Shixian Niu, Dalin Xi, Shuqi Zhao, Jiang Sun, Yong Jiang, Jinghua Liu, 2019 H3K4 methylation regulates LPS-induced proinflammatory cytokine expression and release in macrophages, Shuqi Zhao, Yuyun Zhong, Xiaoxia Fu, Yiqian Wang, Ping Ye, Junwei Cai, Yun Liu, Jiang Sun, Zhuzhong Mei, Yong Jiang, and Jinghua Liu, 2019 Mig6 reduces inflammatory mediators production by regulating the activation of EGFR in LPS-induced endotoxemia, Wenting Chen, Hanhui Zhong, Xiaofei Wang, Qiongni Pang, Jinling Zhuang, Jian Hu, Yeming Chen, Jijie Hu, Jinghua Liu, Jing Tang, 2018 NF-kB activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection, Jinghua Liu, Jing Xiang, Xue Li, Siobhan Blankson, Shuqi Zhao, Junwei Cai, Yong Jiang, H. Paul Redmond, Jiang Huai Wang, 2017 Screening cytokine/chemokine profiles in serum and organs from an endotoxic shock mouse model by LiquiChip, Jinghua Liu, Juan Wang, Haihua Luo, Zhijie Li, Tianyu Zhong, Jing Tang, Yong Jiang, 2017 Kelch-like protein 21 (KLHL21) targets IκB kinase-β to regulate nuclear factor κ-light chain enhancer of activated B cells (NF-κB) signaling negatively, Zhuzhong Mei, Xinyu Chen, Shuiwang Hu, Ni wang, Xiaoli Ou, Jingwang, Haihua Luo, Jinghua Liu, Yong Jiang, 2016 ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance, Jinghua Liu, Julliette M. Buckley, H. Paul Redmond, Jiang Huai Wang, 2010

Areas of Focus

Cell signal transduction in inflammation
Mechanisms of sepsis
Innate immunity training

Publications

Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine, Na Peng, Yan Geng, Jiafu Ouyang, Shuai Liu, Fangfang Yuan, Yantong Wan, Wenda Chen, BaoJun Yu, Youqing Tang, Lei Su, Huaping Liang, Jiang Huai Wang and Jinghua Liu, 2023
Gene expression variability across cells and species shapes the relationship between renal resident macrophages and infiltrated macrophages, Xiangjun Ji, Junwei Cai, Lixin Liang, Tieliu Shi and Jinghua Liu, 2023
Bibliometric and Visual Analysis of Neutrophil Extracellular Traps from 2004 to 2022, Yantong Wan, Junyi Shen, Jiafu Ouyang, Peng Dong, Yinghao Hong, Lixin Liang, Jinghua Liu, 2022
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect, Piao Luo, Qian Zhang, Tian‑Yu Zhong, Jia‑Yun Chen, Jun‑Zhe Zhang, Ya Tian, Liu‑Hai Zheng, Fan Yang, Ling‑Yun Dai, Chang Zou, Zhi‑Jie Li, Zhijie Li, Jinghua Liu, Ji‑Gang Wang, 2022
Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia, Hanhui Zhong, Haitao Lin, Qiongni Pang, Jinling Zhuang, Xiaolei Liu, Xiaolian Li, Jinghua Liu & Jing Tang, 2021
An early neutrophil recruitment into the infectious site is critical for BLP tolerance-afforded protection against microbial sepsis, Wenting Chen, Shuqi Zhao, Michael Ita, Yue Li, Jingjing Ji, Yong Jiang, H. Paul Redmond, Jiang Huai Wang, and Jinghua Liu, 2020
The novel methyltransferase SETD4 regulates TLR agonist-induced expression of cytokines through methylation of lysine 4 at histone 3 in macrophages, Yuyun Zhong, Ping Ye, Zhuzhong Mei, Sui Huang, Mengyi Huang, Li Yue, Shixian Niu, Shuqi Zhao, Junwei Cai, Juan Wang, Yong Jiang, Jinghua Liu, 2019
Rab20 is critical for bacterial lipoprotein tolerization-enhanced bactericidal activity in macrophages during bacterial infection, Shuqi Zhao, Dalin Xi, Junwei Cai, Wenting Chen, Jing Xiang, Na Peng, Juan Wang, Yong Jiang, Zhuzhong Mei and Jinghua Liu, 2019
Differences in LPS-induced inflammatory response between MEFs and BMDMs, Yue Li, Shixian Niu, Dalin Xi, Shuqi Zhao, Jiang Sun, Yong Jiang, Jinghua Liu, 2019
H3K4 methylation regulates LPS-induced proinflammatory cytokine expression and release in macrophages, Shuqi Zhao, Yuyun Zhong, Xiaoxia Fu, Yiqian Wang, Ping Ye, Junwei Cai, Yun Liu, Jiang Sun, Zhuzhong Mei, Yong Jiang, and Jinghua Liu, 2019
Mig6 reduces inflammatory mediators production by regulating the activation of EGFR in LPS-induced endotoxemia, Wenting Chen, Hanhui Zhong, Xiaofei Wang, Qiongni Pang, Jinling Zhuang, Jian Hu, Yeming Chen, Jijie Hu, Jinghua Liu, Jing Tang, 2018
NF-kB activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection, Jinghua Liu, Jing Xiang, Xue Li, Siobhan Blankson, Shuqi Zhao, Junwei Cai, Yong Jiang, H. Paul Redmond, Jiang Huai Wang, 2017
Screening cytokine/chemokine profiles in serum and organs from an endotoxic shock mouse model by LiquiChip, Jinghua Liu, Juan Wang, Haihua Luo, Zhijie Li, Tianyu Zhong, Jing Tang, Yong Jiang, 2017
Kelch-like protein 21 (KLHL21) targets IκB kinase-β to regulate nuclear factor κ-light chain enhancer of activated B cells (NF-κB) signaling negatively, Zhuzhong Mei, Xinyu Chen, Shuiwang Hu, Ni wang, Xiaoli Ou, Jingwang, Haihua Luo, Jinghua Liu, Yong Jiang, 2016
ST2 negatively regulates TLR2 signaling, but is not required for bacterial lipoprotein-induced tolerance, Jinghua Liu, Julliette M. Buckley, H. Paul Redmond, Jiang Huai Wang, 2010

Inflammation Cell Signaling Sepsis Innate Immunity Immune Response Pathophysiology Cytokines Macrophages Endotoxemia Bacterial Infection

Xiaolian Zhang - Wuhan University

Cheng Wen - Central South University

Zhu Zhong Mei - Southern Medical University

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