Professor | Xiaolian Zhang | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Xiaolian Zhang
Contact Information	zhangxiaolian@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

Upload Avatar (500 x 500)

Name

Xiaolian Zhang

Contact Information

zhangxiaolian@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1982-1986 Bachelor in Virology and Molecular Biology, Wuhan University 1986-1989 Master in Virology and Molecular Biology, Wuhan University 1993-1997 PhD in Biochemistry, Hong Kong University of Science and Technology 1997-2001 Postdoctoral Researcher, Department of Zoology, University of Maryland, College Park
Work Experience	1989-1993 Assistant, Lecturer, Department of Microbiology and Immunology, Hubei Medical University 2001 Research Specialist, Department of Zoology, University of Maryland, College Park 2001-2002 Professor, Department of Microbiology and Immunology, Wuhan University 2004 Visiting Researcher, Department of Biochemistry (II), Fukushima Medical University, Japan 2009 Deputy District Chief, Wujia Gang District, Yichang City 2004-present Director, Hubei Key Laboratory of Allergy and Immunology Related Diseases 2004-present Professor, National Key Laboratory of Virology, Wuhan University 2002-present Head of the Department of Immunology, Wuhan University
Awards	2010: National Science Fund for Distinguished Young Scholars 2017: Second Prize, Natural Science Award of the Higher Education Scientific Research Outstanding Achievement Awards (Ranked first) 2010: Second Prize, Chinese Medical Science and Technology Award (Ranked first) 2010: First Prize, Natural Science Award of Hubei Province 2009: Second Prize, Natural Science Achievement Award of Hubei Province (Ranked first) 2010: Selected for the National New Century Talents Project 2009: National Model Worker for Women 2005: Nomination for the China Youth Female Scientist Award 2013: Selected as a Leading Medical Talent of Hubei Province 2004: Selected for the Ministry of Education's New Century Excellent Talents Support Plan 2005: Golden Globe Academic Award at the 6th International Conference on Typhoid and Other Salmonella Diseases 2012: Wuhan March 8th Red Banner Holder 2010: Top Ten Female Science and Technology Workers of Wuhan 2016, 2014, 2013, 2010, 2007: Wuhan University Medical Outstanding Contribution Award multiple times 2008: Zhu Yubi Medical Prize of Wuhan University

University/Lab Affiliation and Title

Wuhan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1982-1986 Bachelor in Virology and Molecular Biology, Wuhan University
1986-1989 Master in Virology and Molecular Biology, Wuhan University
1993-1997 PhD in Biochemistry, Hong Kong University of Science and Technology
1997-2001 Postdoctoral Researcher, Department of Zoology, University of Maryland, College Park

Work Experience

1989-1993 Assistant, Lecturer, Department of Microbiology and Immunology, Hubei Medical University
2001 Research Specialist, Department of Zoology, University of Maryland, College Park
2001-2002 Professor, Department of Microbiology and Immunology, Wuhan University
2004 Visiting Researcher, Department of Biochemistry (II), Fukushima Medical University, Japan
2009 Deputy District Chief, Wujia Gang District, Yichang City
2004-present Director, Hubei Key Laboratory of Allergy and Immunology Related Diseases
2004-present Professor, National Key Laboratory of Virology, Wuhan University
2002-present Head of the Department of Immunology, Wuhan University

Awards

2010: National Science Fund for Distinguished Young Scholars
2017: Second Prize, Natural Science Award of the Higher Education Scientific Research Outstanding Achievement Awards (Ranked first)
2010: Second Prize, Chinese Medical Science and Technology Award (Ranked first)
2010: First Prize, Natural Science Award of Hubei Province
2009: Second Prize, Natural Science Achievement Award of Hubei Province (Ranked first)
2010: Selected for the National New Century Talents Project
2009: National Model Worker for Women
2005: Nomination for the China Youth Female Scientist Award
2013: Selected as a Leading Medical Talent of Hubei Province
2004: Selected for the Ministry of Education's New Century Excellent Talents Support Plan
2005: Golden Globe Academic Award at the 6th International Conference on Typhoid and Other Salmonella Diseases
2012: Wuhan March 8th Red Banner Holder
2010: Top Ten Female Science and Technology Workers of Wuhan
2016, 2014, 2013, 2010, 2007: Wuhan University Medical Outstanding Contribution Award multiple times
2008: Zhu Yubi Medical Prize of Wuhan University

Areas of Focus	Molecular and infection immunology of intracellular pathogens (tuberculosis, hepatitis C virus, and typhoid)
Publications	Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3, Yao Q, Xie Y, Xu D, Qu Z, Wu J, Zhou Y, Wei Y, Xiong H, Zhang XL, 2022 Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway, Qu ZL, Zhou J, Zhou YD, Xie Y, Jiang YJ, Wu J, Luo ZQ, Yin L, Zhang XL, 2020 A highly conserved G-rich consensus sequence in Hepatitis C virus core gene represents a new anti-Hepatitis C target, Wang SR, Min YQ, Wang JQ, Liu CX, Fu BS, Wu F, Wu LY, Qiao ZX, Song YY, Xu GH, Wu ZG, Huang G, Peng NF, Huang R, Mao WX, Peng S, Chen YQ, Zhu Y, Tian T, Zhang XL, Zhou X, 2016 Mycobacterium Tuberculosis mannose-capped lipoarabinomannan induces IL-10-producing B cells and hinders CD4+ Th1 immunity, Yuan CH, Qu ZL, Tang XL, Liu Q, Luo W, Huang C, Pan Q, Zhang XL, 2018 Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication, Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL, 2018 A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette-Guérin Enhances Immunoprotective Effect against Tuberculosis, Sun X, Pan Q, Yuan C, Wang Q, Tang XL, Ding K, Zhou X, Zhang XL, 2016 Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys, Pan Q, Wang Q, Sun X, Xia X, Wu S, Luo F, Zhang XL, 2014 Detection circulating Mycobacterium tuberculosis specific DNA by droplet digital PCR for vaccine evaluation in challenged monkeys and TB diagnosis, Song N, Tan Y, Zhang LY, Wei Luo W, Guan Q, Yan MZ, Zuo RQ, Liu WX, Luo FL, Zhang XL, 2018 Ficolin-2 inhibits Hepatitis C Virus infection, whereas apolipoprotein E3 mediates viral immune escape, Zhao Y, Ren Y, Zhang X, Zhao P, Tao W, Zhong J, Li Q, Zhang XL, 2014 Aptamer-T cell targeted therapy for tumor treatment using sugar metabolism and Click reaction, Liu CG, Wang Y, Zhou X, Zhang XL, 2020 Quantitative analysis of serum-based IgG agalactosylation for tuberculosis auxiliary diagnosis, Liu P, Ren SF, Xie Y, Liu CG, Qin WJ, Zhou YY, Zhang MX, Yang QT, Chen XC, Liu T, Yao QL, Xiao Z, Gu JX, Zhang XL, 2020

Areas of Focus

Molecular and infection immunology of intracellular pathogens (tuberculosis, hepatitis C virus, and typhoid)

Publications

Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3, Yao Q, Xie Y, Xu D, Qu Z, Wu J, Zhou Y, Wei Y, Xiong H, Zhang XL, 2022
Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway, Qu ZL, Zhou J, Zhou YD, Xie Y, Jiang YJ, Wu J, Luo ZQ, Yin L, Zhang XL, 2020
A highly conserved G-rich consensus sequence in Hepatitis C virus core gene represents a new anti-Hepatitis C target, Wang SR, Min YQ, Wang JQ, Liu CX, Fu BS, Wu F, Wu LY, Qiao ZX, Song YY, Xu GH, Wu ZG, Huang G, Peng NF, Huang R, Mao WX, Peng S, Chen YQ, Zhu Y, Tian T, Zhang XL, Zhou X, 2016
Mycobacterium Tuberculosis mannose-capped lipoarabinomannan induces IL-10-producing B cells and hinders CD4+ Th1 immunity, Yuan CH, Qu ZL, Tang XL, Liu Q, Luo W, Huang C, Pan Q, Zhang XL, 2018
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication, Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL, 2018
A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette-Guérin Enhances Immunoprotective Effect against Tuberculosis, Sun X, Pan Q, Yuan C, Wang Q, Tang XL, Ding K, Zhou X, Zhang XL, 2016
Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys, Pan Q, Wang Q, Sun X, Xia X, Wu S, Luo F, Zhang XL, 2014
Detection circulating Mycobacterium tuberculosis specific DNA by droplet digital PCR for vaccine evaluation in challenged monkeys and TB diagnosis, Song N, Tan Y, Zhang LY, Wei Luo W, Guan Q, Yan MZ, Zuo RQ, Liu WX, Luo FL, Zhang XL, 2018
Ficolin-2 inhibits Hepatitis C Virus infection, whereas apolipoprotein E3 mediates viral immune escape, Zhao Y, Ren Y, Zhang X, Zhao P, Tao W, Zhong J, Li Q, Zhang XL, 2014
Aptamer-T cell targeted therapy for tumor treatment using sugar metabolism and Click reaction, Liu CG, Wang Y, Zhou X, Zhang XL, 2020
Quantitative analysis of serum-based IgG agalactosylation for tuberculosis auxiliary diagnosis, Liu P, Ren SF, Xie Y, Liu CG, Qin WJ, Zhou YY, Zhang MX, Yang QT, Chen XC, Liu T, Yao QL, Xiao Z, Gu JX, Zhang XL, 2020

Intracellular Pathogens Tuberculosis Hepatitis C Virus Typhoid Molecular Immunology Infection Immunology Pathogen-Host Interaction Immune Response Viral Infection Bacterial Infection

Binbo Liu - Wuhan University

Cheng Wen - Central South University

Jinghua Liu - Southern Medical University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us