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Lin Li
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Early Embryo
Primordial Germ Cells
Epigenetic Regulation
Single-Cell
Multi-Omics
Dna Methylation
Chromatin State
Reprogramming
Embryo Development
Germ Cell Development
Areas of Focus
- Primordial germ cells
- Epigenetic regulation
Publications
- Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest, Teng Wang, Junhua Peng, Jiaqi Fan, Ni Tang, Rui Hua, Xueliang Zhou, Zhihao Wang, Longfei Wang, Yanling Bai, Xiaowan Quan, Zimeng Wang, Li Zhang, Chen Luo, Weiqing Zhang, Xiangjin Kang, Jianqiao Liu, Lei Li, Lin Li, 2024
- Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination, Yaping Huang, Lin Li, Geng An, Xinyan Yang, Manman Cui, Xiuling Song, Xiaoling Zhang, Jing Lin, Cai Zhou, Jiexiang Zhao, Zhaokai Yao, Ke Song, Shaofang Ren, Xinyu Xia, Cong Wan, Xin Fu, Yu Lan, Xuesong Hu, Wen Wang, Mei Wang, Yi Zheng, Kai Miao, Xiaochun Bai, Andrew Paul Hutchins, Gang Chang, Shuai Gao, Xiao-Yang Zhao, 2023
- A Subpathway and Target Gene Cluster-Based Approach Uncovers lncRNAs Associated with Human Primordial Follicle Activation, Li Zhang, Jiyuan Zou, Zhihao Wang, Lin Li, 2023
- Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection, Jing Wang, Cai Zhou, Shuai Gao, Xiuling Song, Xinyan Yang, Jiaqi Fan, Shaofang Ren, Linzi Ma, Jiexiang Zhao, Manman Cui, Ke Song, Mei Wang, Chaohui Li, Yi Zheng, Fang Luo, Kai Miao, Xiaochun Bai, Andrew P. Hutchins, Lin Li, Gang Chang, Xiao-Yang Zhao, 2022
- Single-cell multi-omics sequencing of human early embryos, Lin Li, Fan Guo, Yun Gao, Yixin Ren, Peng Yuan, Liying Yan, Rong Li, Ying Lian, Jingyun Li, Boqiang Hu, Junpeng Gao, Lu Wen, Fuchou Tang, Qiao J, 2018
- Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution, Li Li, Lin Li, Qingqing Li, Xixi Liu, Xinyi Ma, Jun Yong, Shuai Gao, Xinglong Wu, Yuan Wei, Xiaoye Wang, Wei Wang, Rong Li, Jie Yan, Xiaohui Zhu, Lu WEN, Jie Qiao, Liying Yan, Fuchou Tang, 2021
- 5-Formylcytosine Landscapes of Human Preimplantation Embryos at Single-cell Resolution, Yun Gao, Lin Li, Peng Yuan, Fan Zhai, Yixin Ren, Liying Yan, Rong Li, Ying Lian, Xiaohui Zhu, Xinglong Wu, Kehkooi Kee, Lu Wen, Jie Qiao, Fuchou Tang, 2020
- Single-cell RNA sequencing reveals the sustained immune cell dysfunction in the pathogenesis of sepsis secondary to bacterial pneumonia, Teng Wang, Xianglong Zhang, Zhanguo Liu, Tong Yao, Dongying Zheng, Jianwei Gan, Shuang Yu, Lin Li, Peng Chen, Jian Sun, 2021
- Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media, Baojiang Wu, Lin Li, Bojiang Li, Junpeng Gao, Yanglin Chen, Mengyi Wei, Zhiqing Yang, Baojing Zhang, Shudong Li, Kexin Li, Changshan Wang, M. Azim Surani, Xihe Li, Fuchou Tang, Siqin Bao, 2020
- Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells, Fan Guo, Lin Li, Jingyun Li, Xinglong Wu, Boqiang Hu, Ping Zhu, Lu Wen, Fuchou Tang, 2017
- The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells, Fan Guo, Liying Yan, Hongshan Guo, Lin Li, Boqiang Hu, Yangyu Zhao, Jun Yong, Yuqiong Hu, Xiaoye Wang, Yuan Wei, Wei Wang, Rong Li, Jie Yan, Xu Zhi, Yan Zhang, Hongyan Jin, Wenxin Zhang, Yu Hou, Ping Zhu, Jingyun Li, Ling Zhang, Sirui Liu, Yixin Ren, Xiaohui Zhu, Lu Wen, Yi Qin Gao, Fuchou Tang, Jie Qiao, 2015
- Single-cell sequencing: New insights into pre-implantation development, pluripotency, and germ cells, Li Lin, Gao Shuai, 2019
Awards
- 2022: Guangdong Natural Science Foundation Outstanding Youth Fund Recipient
- 2023: Selected for National Youth Talent Project
