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Xingmei Zhang
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Aptamer
Neurodegenerative Disease
Cancer
Diagnosis
Therapy
Screening
Targeted
Treatment
Tumor
Research
Areas of Focus
- Aptamer screening
- Targeted diagnosis and treatment of neurodegenerative diseases and tumors
Work Experience
- 1997-2000 - First Military Medical University - Biochemistry Department
- 2003-present - Southern Medical University - Associate Professor, Professor
Academic Background & Achievements
- 1994 - Bachelor's degree: Bethune Medical University
- 1997 - Master's degree: Military Medical Academy
- 2003 - Doctorate: Military Medical Academy
Publications
- Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma, Peng L, Liang Y, Zhong X, Liang Z, Tian Y, Li S, Liang J, Wang R, Zhong Y, Shi Y, Zhang X, 2020
- The BACE1-Specific DNA Aptamer A1 Rescues Amyloid-β Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease, Liang ZM, Peng YH, Chen Y, Long LL, Luo HJ, Chen YJ, Liang YL, Tian YH, Li SJ, Shi YS, Zhang XM, 2019
- Effects of aptamer to U87-EGFRvIII cells on the proliferation, radiosensitivity, and radiotherapy of glioblastoma cells, Zhang X, Peng L, Liang Z, Kou Z, Chen Y, Shi G, Li X, Liang Y, Wang F, Shi Y, 2018
- DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro, Tan Y, Shi YS, Wu XD, Liang HY, Gao YB, Li SJ, Zhang XM, Wang F, Gao TM, 2013
- Anti-epitope antibody, a novel site-directed antibody against human acetylcholinesterase, Zhang XM, Liu G, Sun MJ, 2004
- Screening of RNA molecules inhibiting human acetylcholinesterase by systematic evolution of ligands by exponential enrichment, Zhang XM, Shao NS, Chi MG, Sun MJ, 2003
Awards
- 2006 - Second Prize for Military Scientific and Technological Progress: Research on human-derived antitoxic enzymes and their resistance genes for nerve agents
