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Xiaohua Guo
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Age
Vascular Permeability
Signaling Mechanisms
Endothelial Cells
Acute Lung Injury
Epithelial Barrier
Sepsis
Hyperpermeability
Β-Catenin
Adam10
Areas of Focus
- AGE-mediated changes in vascular permeability and signaling mechanisms
- Epithelial barrier dysfunction and signaling mechanisms in sepsis-induced acute lung injury
Work Experience
- 2010-2012 - Postdoctoral Research in the USA
Publications
- SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis, He Q, Chen Z, Li J, Liu J, Zuo Z, Lin B, Song K, Zhou C, Lai H, Huang Q, Guo X, 2023
- Advanced glycation end products induce endothelial hyperpermeability via β-catenin phosphorylation and subsequent up-regulation of ADAM10, Jie Weng, Zhenfeng Chen, Jieyu Li, Qi He, Deshu Chen, Lin Yang, Haiying Su, Junlin Huang, Shengxiang Yu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo, 2021
- Role of the Receptor for Advanced Glycation End Products in Heat Stress-Induced Endothelial Hyperpermeability in Acute Lung Injury, Zhou G, Chen Z, Li J, Guo X, Qin K, Luo J, Hu J, Huang Q, Su L, Guo X, Xu Q, 2020
- Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models, Chen L, Cui Y, Li B, Weng J, Wang W, Zhang S, Huang X, Guo X, Huang Q, 2020
- Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments, Guo X, Eitnier RA, Beard RS Jr, Meegan JE, Yang X, Aponte AM, Wang F, Nelson PR, Wu MH, 2020
- β-Catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability, Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, Lei X, Chen L, Cui Y, Huang Q, Jiang Y, Guo X, 2018
- Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability, Wang W, Weng J, Yu L, Huang Q, Jiang Y, Guo X, 2018
- Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis, Li P, Chen D, Cui Y, Zhang W, Weng J, Yu L, Chen L, Chen Z, Su H, Yu S, Wu J, Huang Q, Guo X, 2018
- Mdia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability, Zhou X, Weng J, Xu J, Xu Q, Wang W, Zhang W, Huang Q, Guo X, 2018
- Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo, Wu F, Guo X, Xu J, Wang W, Li B, Huang Q, Su L, Xu Q, 2016
- Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products, Zhang W, Xu Q, Wu J, Zhou X, Weng J, Xu J, Wang W, Huang Q, Guo X, 2015
Awards
- 2017: Outstanding Teacher of Southern Medical University
