Professor | Xiaohua Guo | Asia Growth Partners

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Name	Xiaohua Guo
Contact Information	lanblue@smu.edu.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Xiaohua Guo

Contact Information

lanblue@smu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Work Experience	2010-2012 - Postdoctoral Research in the USA
Awards	2017: Outstanding Teacher of Southern Medical University

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Work Experience

2010-2012 - Postdoctoral Research in the USA

Awards

2017: Outstanding Teacher of Southern Medical University

Areas of Focus	AGE-mediated changes in vascular permeability and signaling mechanisms Epithelial barrier dysfunction and signaling mechanisms in sepsis-induced acute lung injury
Publications	SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis, He Q, Chen Z, Li J, Liu J, Zuo Z, Lin B, Song K, Zhou C, Lai H, Huang Q, Guo X, 2023 Advanced glycation end products induce endothelial hyperpermeability via β-catenin phosphorylation and subsequent up-regulation of ADAM10, Jie Weng, Zhenfeng Chen, Jieyu Li, Qi He, Deshu Chen, Lin Yang, Haiying Su, Junlin Huang, Shengxiang Yu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo, 2021 Role of the Receptor for Advanced Glycation End Products in Heat Stress-Induced Endothelial Hyperpermeability in Acute Lung Injury, Zhou G, Chen Z, Li J, Guo X, Qin K, Luo J, Hu J, Huang Q, Su L, Guo X, Xu Q, 2020 Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models, Chen L, Cui Y, Li B, Weng J, Wang W, Zhang S, Huang X, Guo X, Huang Q, 2020 Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments, Guo X, Eitnier RA, Beard RS Jr, Meegan JE, Yang X, Aponte AM, Wang F, Nelson PR, Wu MH, 2020 β-Catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability, Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, Lei X, Chen L, Cui Y, Huang Q, Jiang Y, Guo X, 2018 Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability, Wang W, Weng J, Yu L, Huang Q, Jiang Y, Guo X, 2018 Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis, Li P, Chen D, Cui Y, Zhang W, Weng J, Yu L, Chen L, Chen Z, Su H, Yu S, Wu J, Huang Q, Guo X, 2018 Mdia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability, Zhou X, Weng J, Xu J, Xu Q, Wang W, Zhang W, Huang Q, Guo X, 2018 Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo, Wu F, Guo X, Xu J, Wang W, Li B, Huang Q, Su L, Xu Q, 2016 Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products, Zhang W, Xu Q, Wu J, Zhou X, Weng J, Xu J, Wang W, Huang Q, Guo X, 2015

Areas of Focus

AGE-mediated changes in vascular permeability and signaling mechanisms
Epithelial barrier dysfunction and signaling mechanisms in sepsis-induced acute lung injury

Publications

SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis, He Q, Chen Z, Li J, Liu J, Zuo Z, Lin B, Song K, Zhou C, Lai H, Huang Q, Guo X, 2023
Advanced glycation end products induce endothelial hyperpermeability via β-catenin phosphorylation and subsequent up-regulation of ADAM10, Jie Weng, Zhenfeng Chen, Jieyu Li, Qi He, Deshu Chen, Lin Yang, Haiying Su, Junlin Huang, Shengxiang Yu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo, 2021
Role of the Receptor for Advanced Glycation End Products in Heat Stress-Induced Endothelial Hyperpermeability in Acute Lung Injury, Zhou G, Chen Z, Li J, Guo X, Qin K, Luo J, Hu J, Huang Q, Su L, Guo X, Xu Q, 2020
Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models, Chen L, Cui Y, Li B, Weng J, Wang W, Zhang S, Huang X, Guo X, Huang Q, 2020
Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments, Guo X, Eitnier RA, Beard RS Jr, Meegan JE, Yang X, Aponte AM, Wang F, Nelson PR, Wu MH, 2020
β-Catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability, Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, Lei X, Chen L, Cui Y, Huang Q, Jiang Y, Guo X, 2018
Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability, Wang W, Weng J, Yu L, Huang Q, Jiang Y, Guo X, 2018
Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis, Li P, Chen D, Cui Y, Zhang W, Weng J, Yu L, Chen L, Chen Z, Su H, Yu S, Wu J, Huang Q, Guo X, 2018
Mdia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability, Zhou X, Weng J, Xu J, Xu Q, Wang W, Zhang W, Huang Q, Guo X, 2018
Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo, Wu F, Guo X, Xu J, Wang W, Li B, Huang Q, Su L, Xu Q, 2016
Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products, Zhang W, Xu Q, Wu J, Zhou X, Weng J, Xu J, Wang W, Huang Q, Guo X, 2015

Age Vascular Permeability Signaling Mechanisms Endothelial Cells Acute Lung Injury Epithelial Barrier Sepsis Hyperpermeability Β-Catenin Adam10

Sifeng Chen - Fudan University

Meng Xiang - Fudan University

Qiaobing Huang - Southern Medical University

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