Professor | Sifeng Chen | Asia Growth Partners

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Name	Sifeng Chen
Contact Information	chen1216@fudan.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Sifeng Chen

Contact Information

chen1216@fudan.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005-2006 MBA: University of Alabama at Birmingham (Pharmaceutical and Health, In-service) 1985-1988 Master's in Medical Physiology: Second Military Medical University 1980-1985 Bachelor's in Naval Medicine: Second Military Medical University
Work Experience	2006-present - Fudan University - Distinguished Professor 2013-2019.3 - Fudan University Shanghai Medical College - Department Chair of Physiology and Pathophysiology 2008-2019 - Fudan University - Director of Kidney and Hypertension Research Center 2008-2013 - Fudan University Shanghai Medical College - Deputy Chair of Physiology and Pathophysiology (Acting Chair) 2003-2007 - University of Alabama at Birmingham - Assistant Professor in Internal Medicine 2001-2003 - University of Florida - Assistant Research Professor in Internal Medicine 1998-2001 - University of Florida - Postdoctoral Fellow in Internal Medicine 1997-1998 - University of Magdeburg - Humboldt Fellowship in Surgery 1995-1997 - Second Military Medical University - Executive Director of Pathophysiology 1992-1997 - Second Military Medical University - Associate Professor of Pathophysiology 1988-1992 - Second Military Medical University - Lecturer in Pathophysiology
Awards	2016 Shanghai Municipal Education Commission: Shanghai Undergraduate All-English Demonstration Course Pathophysiology 2016 Shanghai Municipal Education Commission: Shanghai International Student English Demonstration Course Pathophysiology 2006 Polish National Science and Technology Progress Award (no ranking), Polish Ministry of Science and Education: International Cooperation Research on the Role of Heme Oxygenase-1 in Diseases 1997 National Science and Technology Progress Award Final Defense (First Author): Mechanism of Acute Lung Injury 1997 Humboldt Fellowship (no ranking) 1997 International Cancer Union Technology Transfer Award (no ranking) 1995 Military Science and Technology Progress Second Prize (First Author): Role and Mechanism of Platelet Activating Factor and Phospholipase A2 in Acute Lung Injury 1995 Military Third-Class Merit 1994 Military Science and Technology Progress Third Prize (First Author): Study on the Regulation of Leukocyte-Endothelial Cell Adhesion on Pulmonary Microvascular Endothelial Monolayer Permeability 1992 Military Science and Technology Progress Second Prize (Fifth Author): Experimental Study on the Mechanism of Acute Lung Injury 1991 Military Science and Technology Progress Third Prize (Third Author): Study on the Damage and Mechanism of Pulmonary Surfactant System in Dogs with Acute Pancreatitis 1990 Military Science and Technology Progress Third Prize (First Author): Study on the Damage and Mechanism of Phospholipase A2 on Perfused Lungs 1989 Military Science and Technology Progress Third Prize (Second Author): Study on Lung Injury Caused by Acute Pancreatitis in Dogs 1989 Military Science and Technology Progress Third Prize (Fourth Author): Stereology of Lamellar Bodies in Type II Alveolar Epithelial Cells in Dogs with Acute Hemorrhagic Pancreatitis

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2005-2006 MBA: University of Alabama at Birmingham (Pharmaceutical and Health, In-service)
1985-1988 Master's in Medical Physiology: Second Military Medical University
1980-1985 Bachelor's in Naval Medicine: Second Military Medical University

Work Experience

2006-present - Fudan University - Distinguished Professor
2013-2019.3 - Fudan University Shanghai Medical College - Department Chair of Physiology and Pathophysiology
2008-2019 - Fudan University - Director of Kidney and Hypertension Research Center
2008-2013 - Fudan University Shanghai Medical College - Deputy Chair of Physiology and Pathophysiology (Acting Chair)
2003-2007 - University of Alabama at Birmingham - Assistant Professor in Internal Medicine
2001-2003 - University of Florida - Assistant Research Professor in Internal Medicine
1998-2001 - University of Florida - Postdoctoral Fellow in Internal Medicine
1997-1998 - University of Magdeburg - Humboldt Fellowship in Surgery
1995-1997 - Second Military Medical University - Executive Director of Pathophysiology
1992-1997 - Second Military Medical University - Associate Professor of Pathophysiology
1988-1992 - Second Military Medical University - Lecturer in Pathophysiology

Awards

2016 Shanghai Municipal Education Commission: Shanghai Undergraduate All-English Demonstration Course Pathophysiology
2016 Shanghai Municipal Education Commission: Shanghai International Student English Demonstration Course Pathophysiology
2006 Polish National Science and Technology Progress Award (no ranking), Polish Ministry of Science and Education: International Cooperation Research on the Role of Heme Oxygenase-1 in Diseases
1997 National Science and Technology Progress Award Final Defense (First Author): Mechanism of Acute Lung Injury
1997 Humboldt Fellowship (no ranking)
1997 International Cancer Union Technology Transfer Award (no ranking)
1995 Military Science and Technology Progress Second Prize (First Author): Role and Mechanism of Platelet Activating Factor and Phospholipase A2 in Acute Lung Injury
1995 Military Third-Class Merit
1994 Military Science and Technology Progress Third Prize (First Author): Study on the Regulation of Leukocyte-Endothelial Cell Adhesion on Pulmonary Microvascular Endothelial Monolayer Permeability
1992 Military Science and Technology Progress Second Prize (Fifth Author): Experimental Study on the Mechanism of Acute Lung Injury
1991 Military Science and Technology Progress Third Prize (Third Author): Study on the Damage and Mechanism of Pulmonary Surfactant System in Dogs with Acute Pancreatitis
1990 Military Science and Technology Progress Third Prize (First Author): Study on the Damage and Mechanism of Phospholipase A2 on Perfused Lungs
1989 Military Science and Technology Progress Third Prize (Second Author): Study on Lung Injury Caused by Acute Pancreatitis in Dogs
1989 Military Science and Technology Progress Third Prize (Fourth Author): Stereology of Lamellar Bodies in Type II Alveolar Epithelial Cells in Dogs with Acute Hemorrhagic Pancreatitis

Areas of Focus	Stem Cell Medicine Mechanisms and Treatment of Vascular Endothelial Diseases Immune Mechanisms and Immunotherapy of Diabetes and Its Complications Acute Lung Injury
Publications	Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix, Yansong Ren, Jinbo Liu, Huijun Xu, Shun Wang, Shirui Li, Meng Xiang, and Sifeng Chen, 2020 Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey, Wang, X., Lu, M., Tian, X., Ren, Y., Li, Y., Xiang, M., and Chen, S., 2020 Induced pluripotent stem cells attenuate chronic allogeneic vasculopathy in an integrin beta-1-dependent manner, Meng Lu, Rong Xue, Pingping Wang, Xiaokai Wang, Xiaoyu Tian, Yingying Liu, Shun Wang, Anfeng Cui, Jingxin Xie, Lili Le, Meng Zhao, Jing Quan, Ning Li, Dan Meng, Xinhong Wang, Ning Sun, Alex F. Chen, Meng Xiang, Sifeng Chen, 2020 新型冠状病毒导致的致命肺渗漏的病理生理学机制和防治策略:兼论血透的应用与依据, 陈思锋, 2020 Enhanced wound healing promotion by immune response-free monkey autologous iPSCs and exosomes vs. their allogeneic counterparts, Meng Lu, Peng Lu, Ming Xu, Xiaokai Wang, Anfeng Cui, Yijun Li, Xinhong Wang, Dan Meng, Ning Sun, Meng Xiang, and Sifeng Chen, 2019 ALIX Increases Protein Content and Protective Function of iPSC-derived Exosomes, Ruiting Sun, Yingying Liu, Meng Lu, Qianqian Ding, Pingping Wang, Heng Zhang, Xiaoyu Tian, Peng Lu, Dan Meng, Ning Sun, Meng Xiang, Sifeng Chen, 2019 Direct in vivo application of induced pluripotent stem cells is feasible and can be safe, Xiang M, Lu M, Quan J, Xu M, Meng D, Cui A, Li N, Liu Y, Lu P, Kang X, Wang X, Sun N, Zhao M, Liang Q, Le L, Wang X, Zhang J, Chen S., 2019 Adeno-associated viral vector-mediated interleukin-10 prolongs allograft survival in a rat kidney transplantation model, Chen B, Kapturczak MH, Joseph R, George JF, Campbell-Thompson M, Wasserfall CH, Atkinson MA, Tisher CC, Flotte TR, Agarwal A, Chen S., 2007 Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway, Chen S, Kapturczak MH, Wasserfall C, Glushakova OY, Campbell-Thompson M, Deshane JS, Joseph R, Cruz PE, Hauswirth WW, Madsen KM, Croker BP, Berns KI, Atkinson MA, Flotte TR, Tisher CC, Agarwal A., 2005 Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors, Chen S, Agarwal A, Glushakova OY, Jorgensen MS, Salgar SK, Poirier A, Flotte TR, Croker BP, Madsen KM, Atkinson MA, Hauswirth WW, Berns KI, Tisher CC., 2003

Areas of Focus

Stem Cell Medicine
Mechanisms and Treatment of Vascular Endothelial Diseases
Immune Mechanisms and Immunotherapy of Diabetes and Its Complications
Acute Lung Injury

Publications

Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix, Yansong Ren, Jinbo Liu, Huijun Xu, Shun Wang, Shirui Li, Meng Xiang, and Sifeng Chen, 2020
Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey, Wang, X., Lu, M., Tian, X., Ren, Y., Li, Y., Xiang, M., and Chen, S., 2020
Induced pluripotent stem cells attenuate chronic allogeneic vasculopathy in an integrin beta-1-dependent manner, Meng Lu, Rong Xue, Pingping Wang, Xiaokai Wang, Xiaoyu Tian, Yingying Liu, Shun Wang, Anfeng Cui, Jingxin Xie, Lili Le, Meng Zhao, Jing Quan, Ning Li, Dan Meng, Xinhong Wang, Ning Sun, Alex F. Chen, Meng Xiang, Sifeng Chen, 2020
新型冠状病毒导致的致命肺渗漏的病理生理学机制和防治策略:兼论血透的应用与依据, 陈思锋, 2020
Enhanced wound healing promotion by immune response-free monkey autologous iPSCs and exosomes vs. their allogeneic counterparts, Meng Lu, Peng Lu, Ming Xu, Xiaokai Wang, Anfeng Cui, Yijun Li, Xinhong Wang, Dan Meng, Ning Sun, Meng Xiang, and Sifeng Chen, 2019
ALIX Increases Protein Content and Protective Function of iPSC-derived Exosomes, Ruiting Sun, Yingying Liu, Meng Lu, Qianqian Ding, Pingping Wang, Heng Zhang, Xiaoyu Tian, Peng Lu, Dan Meng, Ning Sun, Meng Xiang, Sifeng Chen, 2019
Direct in vivo application of induced pluripotent stem cells is feasible and can be safe, Xiang M, Lu M, Quan J, Xu M, Meng D, Cui A, Li N, Liu Y, Lu P, Kang X, Wang X, Sun N, Zhao M, Liang Q, Le L, Wang X, Zhang J, Chen S., 2019
Adeno-associated viral vector-mediated interleukin-10 prolongs allograft survival in a rat kidney transplantation model, Chen B, Kapturczak MH, Joseph R, George JF, Campbell-Thompson M, Wasserfall CH, Atkinson MA, Tisher CC, Flotte TR, Agarwal A, Chen S., 2007
Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway, Chen S, Kapturczak MH, Wasserfall C, Glushakova OY, Campbell-Thompson M, Deshane JS, Joseph R, Cruz PE, Hauswirth WW, Madsen KM, Croker BP, Berns KI, Atkinson MA, Flotte TR, Tisher CC, Agarwal A., 2005
Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors, Chen S, Agarwal A, Glushakova OY, Jorgensen MS, Salgar SK, Poirier A, Flotte TR, Croker BP, Madsen KM, Atkinson MA, Hauswirth WW, Berns KI, Tisher CC., 2003

Stem Cells Regenerative Medicine Vascular Diseases Endothelial Cells Diabetes Immunotherapy Acute Lung Injury Pathophysiology Gene Therapy Translational Research

Dongcheng Wu - Wuhan University

Meng Xiang - Fudan University

Xiaohua Guo - Southern Medical University

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