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Mangmang Li
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Embryonic Stem Cells
Transcriptional Regulation
Mesenchymal Stem Cells
Spinal Cord Injury
Translational Medicine
P53
Cell Differentiation
Stem Cell Development
Gene Therapy
Molecular Biology
Areas of Focus
- Regulation of embryonic stem cell occurrence, development, and differentiation by p53
Work Experience
- 2009-2014 - National Cancer Institute, National Institutes of Health, USA - Postdoctoral Researcher
- 2014-Present - Southern Medical University - Professor of Cell Biology
Academic Background & Achievements
- 2001 - Master's Degree in Science: Sichuan University
- 2008 - Doctorate in Science: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
- 2009-2014 - Postdoctoral Research: National Cancer Institute, National Institutes of Health, USA
- 2017 - Received National Key R&D Program for Stem Cell and Translational Research
Publications
- hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA A receptor, Cao T, Chen H, Huang W, Xu S, Liu P, Zou W, Pang M, Xu Y, Bai X, Liu B, Rong L, Cui ZK, Li M, 2022
- An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells, Li M, Gou H, Tripathi BK, Huang J, Jiang S, Dubois W, Waybright T, Lei M, Shi J, Zhou M, Huang J, 2015
- Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells, Li M, He Y, Dubois W, Wu X, Shi J, Huang J, 2012
- A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells, Lee KH, Li M, Michalowski AM, Zhang X, Liao H, Chen L, Xu Y, Wu X, Huang J, 2010
- Dose optimization of intrathecal administration of human umbilical cord mesenchymal stem cells for the treatment of subacute incomplete spinal cord injury, Cao T, Chen H, Pang M, Xu S, Wen H, Liu B, Rong L, Li M, 2022
- Sall4 Guides p53-Mediated Enhancer Interference upon DNA Damage in Mouse Embryonic Stem Cells, Wang L, Tan X, Chen L, Xu S, Huang W, Chen N, Wu Y, Wang C, Zhou D, Li M, 2022
- Identification of potential regulatory genes for embryonic stem cell self-renewal and pluripotency by random forest, Zeng P, Tang X, Wu T, Tian Q, Li M, Ding J, 2021
- Subarachnoid transplantation of human umbilical cord mesenchymal stem cell in rodent model with subacute incomplete spinal cord injury: Preclinical safety and efficacy study, Yang Y, Cao TT, Tian Z, Gao H, Wen H, Pang M, He W, Wang N, Chen Y, Wang Y, Li H, Lin J, Kang Z, Li M, Liu B, Rong L, 2020
- Genome-wide studies of the transcriptional regulation by p53, Li M, He Y, Feng X, Huang J, 2012
- A new puzzling role of p53 in mouse embryonic stem cells, Li M, Huang J, 2010
- An induced hypersensitive-like response limits expression of foreign peptides via a recombinant TMV-based vector in a susceptible tobacco, Li M, Li P, Song R, Xu Z, 2010
- TMV recombinants encoding fused foreign transmembrane domains to the CP subunit caused local necrotic response on susceptible tobacco, Li Q, Li M, Jiang L, Zhang Q, Song R, Xu Z, 2006
- A modified TMV-based vector facilitates the expression of longer foreign epitopes in tobacco, Jiang L, Li Q, Li M, Zhou Z, Wu L, Fan J, Zhang Q, Zhu H, Xu Z, 2006
- Morphology and stability changes of recombinant TMV particles caused by a cysteine residue in the foreign peptide fused to the coat protein, Li Q, Jiang L, Li M, Li P, Zhang Q, Song R, Xu Z, 2007
Awards
- 2009-2014: Visiting Fellowship from the National Institutes of Health, USA
- 2014-2017: Research Fellowship from the National Institutes of Health, USA
