Professor | Xiaohong Jiang | Asia Growth Partners

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Name	Xiaohong Jiang
Contact Information	xiaohongjiang@nju.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Xiaohong Jiang

Contact Information

xiaohongjiang@nju.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	2006 - Bachelor's Degree: Nanjing University, School of Chemistry and Chemical Engineering 2011 - Doctorate: Nanjing University, School of Life Sciences Studied at University of California, Berkeley during PhD Published over 30 high-level research papers in journals like Nature Communications, PNAS, Diabetologia Received the First Prize of Natural Science Award for Outstanding Scientific Research in Higher Education Institutions
Work Experience	2011-2014 - Assistant Researcher: Nanjing University, School of Life Sciences 2014-present - Associate Professor: Nanjing University 2021-present - Professor: Nanjing University Youth Committee Member: Jiangsu Physiological Society
Awards	2011: First Prize of Natural Science Award for Outstanding Scientific Research in Higher Education Institutions

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

2006 - Bachelor's Degree: Nanjing University, School of Chemistry and Chemical Engineering
2011 - Doctorate: Nanjing University, School of Life Sciences
Studied at University of California, Berkeley during PhD
Published over 30 high-level research papers in journals like Nature Communications, PNAS, Diabetologia
Received the First Prize of Natural Science Award for Outstanding Scientific Research in Higher Education Institutions

Work Experience

2011-2014 - Assistant Researcher: Nanjing University, School of Life Sciences
2014-present - Associate Professor: Nanjing University
2021-present - Professor: Nanjing University
Youth Committee Member: Jiangsu Physiological Society

Awards

2011: First Prize of Natural Science Award for Outstanding Scientific Research in Higher Education Institutions

Areas of Focus	Molecular mechanisms and targeted therapy of obesity and type 2 diabetes Molecular mechanisms and exercise intervention therapy for cardiovascular diseases In vivo targeted delivery systems for small nucleic acid drugs
Publications	Smooth muscle overexpression of PGC1α attenuates atherosclerosis in rabbits., Wei Z, Chong H, Jiang Q, Tang Y, Xu J, Wang H, Shi Y, Cui L, Li J, Zhang Y, Xue Y, Li J, Liu G, Chen X, Wang D, Zhang CY, Jiang X., 2021 Pancreatic β cells control glucose homeostasis via the secretion of exosomal miR-29 family., Li J, Zhang Y, Ye Y, Li D, Liu Y, Lee E, Zhang M, Dai X, Zhang X, Wang S, Zhang J, Jia W, Zen K, Vidal-Puig A, Jiang X, Zhang CY., 2021 Gonadal white adipose tissue-derived exosomal MiR-222 promotes obesity-associated insulin resistance., Li D, Song H, Shuo L, Wang L, Xie P, Li W, Liu J, Tong Y, Zhang CY, Jiang X, Li J, Zhang Y., 2020 An engineered exosome for delivering sg RNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells., Ye Y, Zhang X, Xie F, Xu B, Xie P, Yang T, Shi Q, Zhang CY, Zhang Y, Chen J, Jiang X, Li J., 2020 The PGC-1α/NRF1/miR-378a axis protects vascular smooth muscle cells from FFA-induced proliferation, migration and inflammation in atherosclerosis., Chong H, Wei Z, Namuhan, Sun G, Zheng S, Zhu X, Xue Y, Zhou Q, Guo S, Xu J, Wang H, Cui L, Zhang CY, Jiang X, Wang D., 2020 Gain of metabolic benefit with ablation of miR-149-3p from subcutaneous adipose tissue in diet-induced obese mice., Zheng S, Guo S, Sun G, Shi Y, Wei Z, Tang Y, He F, Shi C, Dai P, Chong H, Samuelson I, Zen K, Zhang CY, Zhang Y, Li J, Jiang X., 2019 Exosomal miRNA: an alternative mediator of cell-to-cell communication., Li J, Jiang X, Wang K., 2019 Extracellular and intracellular microRNAs in pancreatic cancer: from early diagnosis to reducing chemoresistance., Jiang X, Hou D, Wei Z, Zheng S, Zhang Y, Li J., 2019 The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells., Hou D, He F, Ma L, Cao M, Zhou Z, Wei Z, Xue Y, Sang X, Chong H, Tian C, Zheng S, Li J, Zen K, Chen X, Hong Z, Zhang CY, Jiang X., 2018 The Jun/miR-22/HuR regulatory axis contributes to tumorigenesis in colorectal cancer., Liu Y, Chen X, Cheng R, Yang F, Yu M, Wang C, Cui S, Hong Y, Liang H, Liu M, Zhao C, Ding M, Sun W, Liu Z, Sun F, Zhang C, Zhou Z, Jiang, X, Chen X., 2018 Characterization of serum miRNAs as molecular biomarkers for acute Stanford type A aortic dissection diagnosis., Xu Z, Wang Q, Pan J, Sheng X, Hou D, Chong H, Wei Z, Zheng S, Xue Y, Zhou Q, Cao H, Zhang CY, Wang D, Jiang X., 2017 Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16., Ding H, Zheng S, Garcia-Ruiz D, Hou D, Wei Z, Liao Z, Li L, Zhang Y, Han X, Zen K, Zhang CY, Li J, Jiang X., 2016 MicroRNA-19b/221/222 induces endothelial cell dysfunction via suppression of PGC-1α in the progression of atherosclerosis., Xue Y, Wei Z, Ding H, Wang Q, Zhou Z, Zheng S, Zhang Y, Hou D, Liu Y, Zen K, Zhang CY, Li J, Wang D, Jiang X., 2015 MicroRNA-495 induces breast cancer cell migration by targeting JAM-A., Cao M, Nie W, Li J, Zhang Y, Yan X, Guan X, Chen X, Zen K, Zhang CY, Jiang X, Hou D., 2014 Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance through inhibition of PTP1B., Ding H, Zhang Y, Xu C, Hou D, Li J, Zhang Y, Peng W, Zen K, Zhang CY, Jiang X., 2014 Ribonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences., Jiang X, Chen YC, Gong H, Trang P, Lu S, Liu F., 2012 Effective inhibition of cytomegalovirus infection by external guide sequences in mice., Jiang X, Gong H, Chen YC, Vu GP, Trang P, Zhang CY, Lu S, Liu F., 2012 Engineered external guide sequences effectively block viral gene expression and replication in cultured cells., Jiang X, Bai Y, Rider P, Kim K, Zhang CY, Lu S, Liu F., 2011 17beta-estradiol inhibits oleic acid-induced rat VSMC proliferation and migration by restoring PGC-1alpha expression., Jiang X, Zhang Y, Hou D, Zhu L, Xu W, Ding L, Qi X, Sun G, Liu C, Zhang J, Zen K, Xiang Y, Zhang CY., 2010

Areas of Focus

Molecular mechanisms and targeted therapy of obesity and type 2 diabetes
Molecular mechanisms and exercise intervention therapy for cardiovascular diseases
In vivo targeted delivery systems for small nucleic acid drugs

Publications

Smooth muscle overexpression of PGC1α attenuates atherosclerosis in rabbits., Wei Z, Chong H, Jiang Q, Tang Y, Xu J, Wang H, Shi Y, Cui L, Li J, Zhang Y, Xue Y, Li J, Liu G, Chen X, Wang D, Zhang CY, Jiang X., 2021
Pancreatic β cells control glucose homeostasis via the secretion of exosomal miR-29 family., Li J, Zhang Y, Ye Y, Li D, Liu Y, Lee E, Zhang M, Dai X, Zhang X, Wang S, Zhang J, Jia W, Zen K, Vidal-Puig A, Jiang X, Zhang CY., 2021
Gonadal white adipose tissue-derived exosomal MiR-222 promotes obesity-associated insulin resistance., Li D, Song H, Shuo L, Wang L, Xie P, Li W, Liu J, Tong Y, Zhang CY, Jiang X, Li J, Zhang Y., 2020
An engineered exosome for delivering sg RNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells., Ye Y, Zhang X, Xie F, Xu B, Xie P, Yang T, Shi Q, Zhang CY, Zhang Y, Chen J, Jiang X, Li J., 2020
The PGC-1α/NRF1/miR-378a axis protects vascular smooth muscle cells from FFA-induced proliferation, migration and inflammation in atherosclerosis., Chong H, Wei Z, Namuhan, Sun G, Zheng S, Zhu X, Xue Y, Zhou Q, Guo S, Xu J, Wang H, Cui L, Zhang CY, Jiang X, Wang D., 2020
Gain of metabolic benefit with ablation of miR-149-3p from subcutaneous adipose tissue in diet-induced obese mice., Zheng S, Guo S, Sun G, Shi Y, Wei Z, Tang Y, He F, Shi C, Dai P, Chong H, Samuelson I, Zen K, Zhang CY, Zhang Y, Li J, Jiang X., 2019
Exosomal miRNA: an alternative mediator of cell-to-cell communication., Li J, Jiang X, Wang K., 2019
Extracellular and intracellular microRNAs in pancreatic cancer: from early diagnosis to reducing chemoresistance., Jiang X, Hou D, Wei Z, Zheng S, Zhang Y, Li J., 2019
The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells., Hou D, He F, Ma L, Cao M, Zhou Z, Wei Z, Xue Y, Sang X, Chong H, Tian C, Zheng S, Li J, Zen K, Chen X, Hong Z, Zhang CY, Jiang X., 2018
The Jun/miR-22/HuR regulatory axis contributes to tumorigenesis in colorectal cancer., Liu Y, Chen X, Cheng R, Yang F, Yu M, Wang C, Cui S, Hong Y, Liang H, Liu M, Zhao C, Ding M, Sun W, Liu Z, Sun F, Zhang C, Zhou Z, Jiang, X, Chen X., 2018
Characterization of serum miRNAs as molecular biomarkers for acute Stanford type A aortic dissection diagnosis., Xu Z, Wang Q, Pan J, Sheng X, Hou D, Chong H, Wei Z, Zheng S, Xue Y, Zhou Q, Cao H, Zhang CY, Wang D, Jiang X., 2017
Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16., Ding H, Zheng S, Garcia-Ruiz D, Hou D, Wei Z, Liao Z, Li L, Zhang Y, Han X, Zen K, Zhang CY, Li J, Jiang X., 2016
MicroRNA-19b/221/222 induces endothelial cell dysfunction via suppression of PGC-1α in the progression of atherosclerosis., Xue Y, Wei Z, Ding H, Wang Q, Zhou Z, Zheng S, Zhang Y, Hou D, Liu Y, Zen K, Zhang CY, Li J, Wang D, Jiang X., 2015
MicroRNA-495 induces breast cancer cell migration by targeting JAM-A., Cao M, Nie W, Li J, Zhang Y, Yan X, Guan X, Chen X, Zen K, Zhang CY, Jiang X, Hou D., 2014
Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance through inhibition of PTP1B., Ding H, Zhang Y, Xu C, Hou D, Li J, Zhang Y, Peng W, Zen K, Zhang CY, Jiang X., 2014
Ribonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences., Jiang X, Chen YC, Gong H, Trang P, Lu S, Liu F., 2012
Effective inhibition of cytomegalovirus infection by external guide sequences in mice., Jiang X, Gong H, Chen YC, Vu GP, Trang P, Zhang CY, Lu S, Liu F., 2012
Engineered external guide sequences effectively block viral gene expression and replication in cultured cells., Jiang X, Bai Y, Rider P, Kim K, Zhang CY, Lu S, Liu F., 2011
17beta-estradiol inhibits oleic acid-induced rat VSMC proliferation and migration by restoring PGC-1alpha expression., Jiang X, Zhang Y, Hou D, Zhu L, Xu W, Ding L, Qi X, Sun G, Liu C, Zhang J, Zen K, Xiang Y, Zhang CY., 2010

Obesity Type 2 Diabetes Molecular Mechanisms Targeted Therapy Cardiovascular Diseases Exercise Intervention Small Nucleic Acid Drugs In Vivo Delivery Metabolic Diseases Mitochondrial Function

Liangliang Fan - Central South University

Ke Tie - Huazhong University of Science and Technology

Yidong Shen - University of Chinese Academy of Sciences

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