Professor | Xingxin Wu | Asia Growth Partners

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Name	Xingxin Wu
Contact Information	xingxin.wu@nju.edu.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Xingxin Wu

Contact Information

xingxin.wu@nju.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	2001.9–2005.6 Bachelor in Biotechnology: Nanjing University 2005.9–2010.6 Doctorate in Biology: Nanjing University
Work Experience	2010.8–2013.12 - Yale University School of Medicine - Postdoctoral Researcher 2014.1–2018.4 - Nanjing University - Associate Researcher 2018.5–Present - Nanjing University - Professor, Doctoral Supervisor
Awards	2018: Ministry of Education Higher Education Scientific Research Outstanding Achievement Award in Natural Science - First Prize 2018: Jiangsu Province Education and Teaching Research Achievement Award - Second Prize 2018: Jiangsu Province Six Talent Peaks - Talent Project 2017: Nanjing City 12th Excellent Academic Paper in Natural Science - Second Prize 2017: Roche Diagnostics Scientific Research Achievement Award Fund - Achievement Award

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

2001.9–2005.6 Bachelor in Biotechnology: Nanjing University
2005.9–2010.6 Doctorate in Biology: Nanjing University

Work Experience

2010.8–2013.12 - Yale University School of Medicine - Postdoctoral Researcher
2014.1–2018.4 - Nanjing University - Associate Researcher
2018.5–Present - Nanjing University - Professor, Doctoral Supervisor

Awards

2018: Ministry of Education Higher Education Scientific Research Outstanding Achievement Award in Natural Science - First Prize
2018: Jiangsu Province Education and Teaching Research Achievement Award - Second Prize
2018: Jiangsu Province Six Talent Peaks - Talent Project
2017: Nanjing City 12th Excellent Academic Paper in Natural Science - Second Prize
2017: Roche Diagnostics Scientific Research Achievement Award Fund - Achievement Award

Areas of Focus	Selective Immunosuppression Homeostasis Reconstruction Receptor Fate in Chemical Biology
Publications	Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis, Yang Tan, Xueqing Sun, Yizhu Xu, Bingjie Tang, Shuaiqi Xu, Dong Lu, Yan Ye, Xiaomin Luo, Xu Diao, Fulong Li, Tianyi Wang, Jiayu Chen, Qiang Xu, Xingxin Wu, 2022 CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy, Li, X. F., M. J. Lu, M. M. Yuan, J. Ye, W. Zhang, L. Y. Xu, X. H. Wu, B. Q. Hui, Y. C. Yang, B. Wei, C. L. Guo, M. Wei, J. Dong, X. X. Wu, Y. H. Gu, 2022 Role of CXCR3 signaling in response to anti-PD-1 therapy, Han Xiao, Wang Ying, Sun Jing, Tan Tao, Cai Xiaomin, Lin Peinan, Tan Yang, Zheng Bingfeng, Wang Biao, Wang Jiawei, Xu Lingyan, Yu Zhengyi, Xu Qiang, Wu Xingxin, Gu Yanhong, 2019 CUG-binding protein 1 regulates HSC activation and liver fibrogenesis, Xingxin Wu, Xudong Wu, Yuxiang Ma, Fenli Shao, Yang Tan, Tao Tan, Liyun Gu, Yang Zhou, Beicheng Sun, Yang Sun, Xuefeng Wu, Qiang Xu, 2016 Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88, Shao, F. Tao Tan, Yang Tan, Yang Sun, Xingxin Wu, Qiang Xu, 2016 T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo, Xingxin Wu, Amit Lahiri, Ritu Sarin, Clara Abraham, 2015 NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury, Xingxin Wu, Amit Lahiri, G. Kenneth Haines, 3rd, Richard A. Flavell, Clara Abraham, 2014 Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis, Xingxin Wu, Wenjie Guo, Limei Wu, Yanhong Gu, Liyun Gu, Suhai Xu, Xuefeng Wu, Yan Shen, Yuehai Ke, Renxiang Tan, Yang Sun, Qiang Xu, 2012 Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses, Sarin R, Xingxin Wu, Abraham C, 2011

Areas of Focus

Selective Immunosuppression
Homeostasis Reconstruction
Receptor Fate in Chemical Biology

Publications

Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis, Yang Tan, Xueqing Sun, Yizhu Xu, Bingjie Tang, Shuaiqi Xu, Dong Lu, Yan Ye, Xiaomin Luo, Xu Diao, Fulong Li, Tianyi Wang, Jiayu Chen, Qiang Xu, Xingxin Wu, 2022
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy, Li, X. F., M. J. Lu, M. M. Yuan, J. Ye, W. Zhang, L. Y. Xu, X. H. Wu, B. Q. Hui, Y. C. Yang, B. Wei, C. L. Guo, M. Wei, J. Dong, X. X. Wu, Y. H. Gu, 2022
Role of CXCR3 signaling in response to anti-PD-1 therapy, Han Xiao, Wang Ying, Sun Jing, Tan Tao, Cai Xiaomin, Lin Peinan, Tan Yang, Zheng Bingfeng, Wang Biao, Wang Jiawei, Xu Lingyan, Yu Zhengyi, Xu Qiang, Wu Xingxin, Gu Yanhong, 2019
CUG-binding protein 1 regulates HSC activation and liver fibrogenesis, Xingxin Wu, Xudong Wu, Yuxiang Ma, Fenli Shao, Yang Tan, Tao Tan, Liyun Gu, Yang Zhou, Beicheng Sun, Yang Sun, Xuefeng Wu, Qiang Xu, 2016
Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88, Shao, F. Tao Tan, Yang Tan, Yang Sun, Xingxin Wu, Qiang Xu, 2016
T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo, Xingxin Wu, Amit Lahiri, Ritu Sarin, Clara Abraham, 2015
NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury, Xingxin Wu, Amit Lahiri, G. Kenneth Haines, 3rd, Richard A. Flavell, Clara Abraham, 2014
Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis, Xingxin Wu, Wenjie Guo, Limei Wu, Yanhong Gu, Liyun Gu, Suhai Xu, Xuefeng Wu, Yan Shen, Yuehai Ke, Renxiang Tan, Yang Sun, Qiang Xu, 2012
Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses, Sarin R, Xingxin Wu, Abraham C, 2011

Autoimmune Diseases Immunosuppression Drug Development Inflammatory Bowel Disease Psoriasis Rheumatoid Arthritis Liver Fibrosis Homeostasis Receptor Dynamics Small Molecules

Hua Gu - Tongji University

Hua Gu - Tongji University

Xuefeng Wu - Nanjing University

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