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Xingxin Wu
Life Science
Nanjing University
Jiangsu
Language: English, Chinese
Autoimmune Diseases
Immunosuppression
Drug Development
Inflammatory Bowel Disease
Psoriasis
Rheumatoid Arthritis
Liver Fibrosis
Homeostasis
Receptor Dynamics
Small Molecules
Areas of Focus
- Selective Immunosuppression
- Homeostasis Reconstruction
- Receptor Fate in Chemical Biology
Work Experience
- 2010.8–2013.12 - Yale University School of Medicine - Postdoctoral Researcher
- 2014.1–2018.4 - Nanjing University - Associate Researcher
- 2018.5–Present - Nanjing University - Professor, Doctoral Supervisor
Academic Background & Achievements
- 2001.9–2005.6 Bachelor in Biotechnology: Nanjing University
- 2005.9–2010.6 Doctorate in Biology: Nanjing University
Publications
- Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis, Yang Tan, Xueqing Sun, Yizhu Xu, Bingjie Tang, Shuaiqi Xu, Dong Lu, Yan Ye, Xiaomin Luo, Xu Diao, Fulong Li, Tianyi Wang, Jiayu Chen, Qiang Xu, Xingxin Wu, 2022
- CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy, Li, X. F., M. J. Lu, M. M. Yuan, J. Ye, W. Zhang, L. Y. Xu, X. H. Wu, B. Q. Hui, Y. C. Yang, B. Wei, C. L. Guo, M. Wei, J. Dong, X. X. Wu, Y. H. Gu, 2022
- Role of CXCR3 signaling in response to anti-PD-1 therapy, Han Xiao, Wang Ying, Sun Jing, Tan Tao, Cai Xiaomin, Lin Peinan, Tan Yang, Zheng Bingfeng, Wang Biao, Wang Jiawei, Xu Lingyan, Yu Zhengyi, Xu Qiang, Wu Xingxin, Gu Yanhong, 2019
- CUG-binding protein 1 regulates HSC activation and liver fibrogenesis, Xingxin Wu, Xudong Wu, Yuxiang Ma, Fenli Shao, Yang Tan, Tao Tan, Liyun Gu, Yang Zhou, Beicheng Sun, Yang Sun, Xuefeng Wu, Qiang Xu, 2016
- Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88, Shao, F. Tao Tan, Yang Tan, Yang Sun, Xingxin Wu, Qiang Xu, 2016
- T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo, Xingxin Wu, Amit Lahiri, Ritu Sarin, Clara Abraham, 2015
- NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury, Xingxin Wu, Amit Lahiri, G. Kenneth Haines, 3rd, Richard A. Flavell, Clara Abraham, 2014
- Selective sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2 ameliorates murine experimental colitis, Xingxin Wu, Wenjie Guo, Limei Wu, Yanhong Gu, Liyun Gu, Suhai Xu, Xuefeng Wu, Yan Shen, Yuehai Ke, Renxiang Tan, Yang Sun, Qiang Xu, 2012
- Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses, Sarin R, Xingxin Wu, Abraham C, 2011
Awards
- 2018: Ministry of Education Higher Education Scientific Research Outstanding Achievement Award in Natural Science - First Prize
- 2018: Jiangsu Province Education and Teaching Research Achievement Award - Second Prize
- 2018: Jiangsu Province Six Talent Peaks - Talent Project
- 2017: Nanjing City 12th Excellent Academic Paper in Natural Science - Second Prize
- 2017: Roche Diagnostics Scientific Research Achievement Award Fund - Achievement Award
