Professor | Yang Shen | Asia Growth Partners

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Name	Yang Shen
Contact Information	shenyang@scu.edu.cn
Language ability	English, Chinese
Province	Sichuan

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Name

Yang Shen

Contact Information

shenyang@scu.edu.cn

Language ability

English, Chinese

Province

Sichuan

University/Lab Affiliation and Title	Sichuan University
Faculty	West China Institute of Basic Medicine and Forensic Medicine
Academic Background & Achievements	2009 - PhD in Biomedical Engineering: Chongqing University Conducted research on vascular stent material surface modification at University of Missouri-Columbia in 2007 Conducted research on central nervous system nano-targeted drug delivery at University of Pittsburgh in 2015
Work Experience	2009-present - Sichuan University - Teaching and research in biomedical engineering 2015 - University of Pittsburgh - Research on central nervous system nano-targeted drug delivery
Awards	2022: Gold Award Guiding Teacher at the 8th National Undergraduate Basic Medicine Innovation Research and Experimental Design Forum National Finals 2021: Silver Award Guiding Teacher at the 7th National Undergraduate Basic Medicine Innovation Research and Experimental Design Forum National Finals 2023: Gold Award Guiding Teacher at the 9th National 'Internet+' College Student Innovation and Entrepreneurship Competition Provincial Competition 2022: Outstanding Guiding Teacher for Sichuan University Basic Discipline Top Talent Training 2016, 2019, 2020: Sichuan University Classroom Teaching Quality Excellence Award 2012, 2017: Most Popular Teacher for Sichuan University Cultural Quality Elective Course 2015-2016: Outstanding Guiding Teacher for Sichuan University Undergraduate Teaching Internship 2011-2013: Sichuan University Backbone Teacher

University/Lab Affiliation and Title

Sichuan University

Faculty

West China Institute of Basic Medicine and Forensic Medicine

Academic Background & Achievements

2009 - PhD in Biomedical Engineering: Chongqing University
Conducted research on vascular stent material surface modification at University of Missouri-Columbia in 2007
Conducted research on central nervous system nano-targeted drug delivery at University of Pittsburgh in 2015

Work Experience

2009-present - Sichuan University - Teaching and research in biomedical engineering
2015 - University of Pittsburgh - Research on central nervous system nano-targeted drug delivery

Awards

2022: Gold Award Guiding Teacher at the 8th National Undergraduate Basic Medicine Innovation Research and Experimental Design Forum National Finals
2021: Silver Award Guiding Teacher at the 7th National Undergraduate Basic Medicine Innovation Research and Experimental Design Forum National Finals
2023: Gold Award Guiding Teacher at the 9th National 'Internet+' College Student Innovation and Entrepreneurship Competition Provincial Competition
2022: Outstanding Guiding Teacher for Sichuan University Basic Discipline Top Talent Training
2016, 2019, 2020: Sichuan University Classroom Teaching Quality Excellence Award
2012, 2017: Most Popular Teacher for Sichuan University Cultural Quality Elective Course
2015-2016: Outstanding Guiding Teacher for Sichuan University Undergraduate Teaching Internship
2011-2013: Sichuan University Backbone Teacher

Areas of Focus	Pathogenesis and interventional treatment of cardiovascular and cerebrovascular diseases Mechanics-biology signal coupling and transduction mechanisms Nano drug delivery strategies for cardiovascular diseases Development of microfluidic organ-on-chip in vitro disease models
Publications	Cathepsin K Contributed to Disturbed Flow-induced Atherosclerosis is Dependent on Integrin-actin Cytoskeleton-NF-κB Pathway, Fei Fang, Tang Feng, Jianwei Li, Huaiyi Zhang, Qin Wang, Yidan Chen, Guixue Wang, Yang Shen, Xiaoheng Liu, 2023 Cardiovasc Res, Xiaoli Wang, Yang Shen, Min Shang, Xiaoheng Liu, Lance L Munn, 2023 Vascular Smooth Muscle Cells in Intracranial Aneurysms, Zhenye Wang, Jia Ma, Hongyan Yue, Zhewei Zhang, Fei Fang, Guixue Wang, Xiaoheng Liu, Yang Shen, 2023 Inflammatory Endothelium-targeted and Cathepsin Responsive Nanoparticles are Effective Against Atherosclerosis, Fei Fang, Yinghao Ni, Hongchi Yu, Hongmei Yin, Fan Yang, Chunli Li, Denglian Sun, Tong Pei, Jia Ma, Li Deng, Huaiyi Zhang, Guixue Wang, Song Li, Yang Shen* and Xiaoheng Liu, 2022 Fluid Shear Stress Activates YAP to Promote Epithelial-mesenchymal Transition in Hepatocellular Carcinoma, Hongchi Yu, Jia He, Guanyue Su, Yuelong Wang, Fei Fang, Wenxing Yang, Kaiyun Gu, Nai Yang Fu, Yunbing Wang, Yang Shen, Xiaoheng Liu, 2021 The Combined Contribution of Vascular Endothelial Cell Migration and Adhesion to Stent Re-endothelialization, Xiaoli Wang, Fei Fang, Yinghao Ni, Hongchi Yu, Jia Ma, Li Deng, Chunli Li, Yang Shen* and Xiaoheng Liu, 2021 ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood-brain barrier, Yang Shen, Bin Cao, Noah R. Snyder, Kevin M. Woeppel, James R. Eles, Xinyan Tracy Cui, 2018 Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration, Yang Shen, Min Gao, Yunlong Ma, Hongchi Yu, Fu-zhai Cui, Hans Gregersen, Qingsong Yu, Guixue Wang, Xiaoheng Liu, 2015 Integrins-FAK-Rho GTPases Pathway in Endothelial Cells Sense and Response to Surface Wettability of Plasma Nanocoatings, Yang Shen, Yunlong Ma, Min Gao, Yi Lai, Guixue Wang, Qingsong Yu, Fu-zhai Cui, Xiaoheng Liu, 2013 Investigation of surface endothelialization on biomedical nitinol (NiTi) alloy: Effects of surface micro-patterning combined with plasma nanocoating, Yang Shen, Guixue Wang, Liang Chen, Hao Li, Ping Yu, Mengjun Bai, Qin Zhang, James Lee, Qingsong Yu, 2009

Areas of Focus

Pathogenesis and interventional treatment of cardiovascular and cerebrovascular diseases
Mechanics-biology signal coupling and transduction mechanisms
Nano drug delivery strategies for cardiovascular diseases
Development of microfluidic organ-on-chip in vitro disease models

Publications

Cathepsin K Contributed to Disturbed Flow-induced Atherosclerosis is Dependent on Integrin-actin Cytoskeleton-NF-κB Pathway, Fei Fang, Tang Feng, Jianwei Li, Huaiyi Zhang, Qin Wang, Yidan Chen, Guixue Wang, Yang Shen*, Xiaoheng Liu*, 2023
Cardiovasc Res, Xiaoli Wang, Yang Shen, Min Shang, Xiaoheng Liu, Lance L Munn, 2023
Vascular Smooth Muscle Cells in Intracranial Aneurysms, Zhenye Wang, Jia Ma, Hongyan Yue, Zhewei Zhang, Fei Fang, Guixue Wang, Xiaoheng Liu, Yang Shen*, 2023
Inflammatory Endothelium-targeted and Cathepsin Responsive Nanoparticles are Effective Against Atherosclerosis, Fei Fang, Yinghao Ni, Hongchi Yu, Hongmei Yin, Fan Yang, Chunli Li, Denglian Sun, Tong Pei, Jia Ma, Li Deng, Huaiyi Zhang, Guixue Wang, Song Li*, Yang Shen* and Xiaoheng Liu*, 2022
Fluid Shear Stress Activates YAP to Promote Epithelial-mesenchymal Transition in Hepatocellular Carcinoma, Hongchi Yu, Jia He, Guanyue Su, Yuelong Wang, Fei Fang, Wenxing Yang, Kaiyun Gu, Nai Yang Fu, Yunbing Wang*, Yang Shen*, Xiaoheng Liu*, 2021
The Combined Contribution of Vascular Endothelial Cell Migration and Adhesion to Stent Re-endothelialization, Xiaoli Wang, Fei Fang, Yinghao Ni, Hongchi Yu, Jia Ma, Li Deng, Chunli Li, Yang Shen* and Xiaoheng Liu*, 2021
ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood-brain barrier, Yang Shen, Bin Cao, Noah R. Snyder, Kevin M. Woeppel, James R. Eles, Xinyan Tracy Cui, 2018
Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration, Yang Shen, Min Gao, Yunlong Ma, Hongchi Yu, Fu-zhai Cui, Hans Gregersen, Qingsong Yu, Guixue Wang, Xiaoheng Liu*, 2015
Integrins-FAK-Rho GTPases Pathway in Endothelial Cells Sense and Response to Surface Wettability of Plasma Nanocoatings, Yang Shen, Yunlong Ma, Min Gao, Yi Lai, Guixue Wang, Qingsong Yu, Fu-zhai Cui, Xiaoheng Liu, 2013
Investigation of surface endothelialization on biomedical nitinol (NiTi) alloy: Effects of surface micro-patterning combined with plasma nanocoating, Yang Shen, Guixue Wang, Liang Chen, Hao Li, Ping Yu, Mengjun Bai, Qin Zhang, James Lee, Qingsong Yu, 2009

Cardiovascular Cerebrovascular Pathogenesis Interventional Treatment Signal Coupling Transduction Nano Drug Delivery Microfluidic Organ-On-Chip Disease Models

Ye Zeng - Sichuan University

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