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Ye Zeng
Basic Medicine and Forensic Medicine
Sichuan University
Sichuan
Language: English, Chinese
Cardiovascular
Cerebrovascular
Endothelial Cells
Foam Cells
Atherosclerosis
Microcirculation
Sepsis
Tumor Microenvironment
Angiogenesis
Metastasis
Areas of Focus
- Prevention, diagnosis, and treatment of cardiovascular and cerebrovascular diseases
- Microcirculation disorders and their treatment
- Tumor microenvironment and its intervention
Work Experience
- 2011-2014 - City College of New York, Biomedical Engineering Department, Postdoctoral Researcher
- 2014-2017 - Sichuan University, West China School of Basic Medical Sciences & Forensic Medicine, Specially Appointed Associate Researcher
Academic Background & Achievements
- 2011 - Doctor of Medicine: Sichuan University, Basic Medicine (Medical Biochemistry and Cell Biology)
- Led 2 National Natural Science Foundation projects, 2 provincial projects, and 5 technical development projects
- Published over 100 SCI papers, with over 60 as first or corresponding author
- Co-authored 8 monographs
- Granted 11 invention patents
Publications
- Glycocalyx acts as a central player in the development of tumor microenvironment by extracellular vesicles for angiogenesis and metastasis., ZENG Y, QIU Y, JIANG W, FU BM, 2022
- Biological features of extracellular vesicles and challenges., ZENG Y, QIU Y, JIANG W, SHEN J, YAO X, HE X, LI L, FU B, LIU X, 2022
- Mechanism of cell death of endothelial cells regulated by mechanical forces., ZENG Y, DU X, YAO X, QIU Y, JIANG W, SHEN J, LI L, LIU X, 2022
- MiR-9 promotes angiogenesis via targeting on sphingosine-1-phosphate receptor 1., YAO XH, XIE LS, ZENG Y, 2020
- Anti-angiogenesis triggers exosomes release from endothelial cells to promote tumor vasculogenesis., ZENG Y, YAO X, LIU X, HE X, LI L, LIU X, YAN Z, WU J, FU BM, 2019
- The role of endothelial surface glycocalyx in mechanosensing and transduction., ZENG Y, ZHANG XF, FU BM, TARBELL JM, 2018
- Role of glypican-1 in endothelial NOS activation under various shear stress magnitudes., ZENG Y, LIU JX, 2016
- Sphingosine 1-phosphate induced synthesis of glycocalyx on endothelial cells., ZENG Y, LIU XH, TARBELL JM, FU BM, 2015
- Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding., ZENG Y, ADAMSON RH, CURRY FR, TARBELL JM, 2014
- Numerical simulation of the effect of permeability on the hydrodynamics in a parallel-plate coculture flow chamber., ZENG Y, YAO XH, LIU XH, 2014
- Fluid shear stress induces the clustering of heparan sulfate via mobility of glypican-1 in lipid rafts., ZENG Y, WATERS M, ANDREWS A, HONARMANDI P, EBONG E, RIZZO V, Tarbell JM, 2013
