Areas of Focus
- Epigenetic regulation mechanisms in tumorigenesis, proliferation, metastasis, and drug resistance
- 3D genome function and gene expression regulation mechanisms, gene function identification
- Development of next-generation multi-omics technologies
Work Experience
- 2021.10-present - Huazhong Agricultural University - Researcher, Doctoral Supervisor
- 2023.07-present - Huazhong Agricultural University - Member of Youth Federation
- 2020.07-2021.07 - German Cancer Research Center - Senior Postdoctoral Researcher in Epigenetics (Molecular Neuroscience)
- 2019.01-2020.06 - Netherlands Cancer Institute - Postdoctoral Researcher in Epigenetics (Oncology)
Academic Background & Achievements
- 2013.09-2019.01 Doctorate in Epigenetics/Genomics: Erasmus University Rotterdam/Netherlands Cancer Institute
- 2010.09-2013.07 Master's in Biochemistry and Molecular Biology: Beijing Normal University
- 2006.09-2010.07 Bachelor's in Biotechnology: Nanjing Agricultural University
Publications
- A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis, Li Li*, Alejandro P Ugalde*, Colinda LGJ Scheele, Sebastian M. Dieter, Remco Nagel, Jin Ma, Abhijeet Pataskar, Gozde Korkmaz, Ran Elkon, Miao-Ping Chien, Reuven Agami, 2021
- LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS, Li Li, Pieter C van Breugel, Fabricio Loayza-Puch, Alejandro Pineiro Ugalde, Gozde Korkmaz, Naama Messika-Gold, Ruiqi Han, Ran Elkon, Reuven Agami, 2018
- Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence, Ruiqi Han*, Li Li*, Alejandro Piñeiro Ugalde, Arieh Tal, Zohar Manber, Eric Pinto Barbera, Veronica Della Chiara, Ran Elkon & Reuven Agami, 2018
- The synthesized transporter K16APoE enabled the therapeutic HAYED peptide to cross the blood-brain barrier and remove excess iron and radicals in the brain, thus easing Alzheimer’s disease, Zhenyou Zou#, Qiqiong Shen, Yanxia Pang, Xin Li, Yongfeng Chen, Xinjuan Wang, Xinhua Luo#, Li Li#, Yizi Li & Hong Lin, 2018
- The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells, Yang,Y., Yang,H., Yang,J., Li, Li., Xiang,B. and Wei,Q., 2017
- Calcineurin subunit B upregulates beta-interferon production by phosphorylation of interferon regulatory factor 3 via Toll-like receptor 4, Wang, X., Li, Li., Huang, Y. and Wei, Q., 2012
Awards
- Hubei High-Level Talent Program (2023): Recognized for outstanding contributions
- Wuhan Talent Program (2021): Recognized as an outstanding young talent
- DKFZ International Postdoctoral Fellowship (2019): One of 10 recipients
- The RNAtrain Grant (2014): One of 13 global recipients
- National Scholarship (2012): Awarded by the Ministry of Education, China
- National Scholarship (2009): Awarded by the Ministry of Education, China
