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Wei Xu
Life Science
Huazhong Agricultural University
Hubei
Language: English, Chinese
Gene Editing
Microbial
Technology
Application
Biosynthesis
Natural Products
Microorganisms
Pathways
Exploration
Analysis
Areas of Focus
- Development and application of microbial gene editing technology
- Exploration and analysis of biosynthetic pathways of natural products from microorganisms
Work Experience
- 2017-07 to 2018-12 - Wuhan University - Research Assistant
- 2019-02 to 2020-04 - Agency for Science, Technology and Research, Singapore - Scientist I
- 2020-04 to 2022-01 - Agency for Science, Technology and Research, Singapore - Scientist I
- 2022-02 to present - Huazhong Agricultural University - Associate Researcher
Academic Background & Achievements
- 2007-09 to 2011-06 Bachelor in Pharmacy: Wuhan University
- 2011-09 to 2017-06 PhD in Biochemistry and Molecular Biology: Wuhan University
Publications
- An Iterative Module in the Azalomycin F Polyketide Synthase Contains a Switchable Enoylreductase Domain., Wei Xu, Guifa Zhai, Yuanzhen Liu, Yuan Li, Yanrong Shi, Kui Hong, Hui Hong, Peter F. Leadlay, Zixin Deng, and Yuhui Sun., 2017
- Emerging Molecular Biology Tools and Strategies for Engineering Natural Product Biosynthesis., Wei Xu, Evaldas Klumbys, Ee Lui Ang, and Huimin Zhao., 2020
- Nitrilase Superfamily Aryl Acylamidase from the Halotolerant Mangrove Streptomyces Sp. 211726., Yanling Ma, Wei Xu, Jun Zhang, Sihong Zhang, Kui Hong, Zixin Deng, and Yuhui Sun., 2014
- Highly Efficient Editing of the Actinorhodin Polyketide Chain Length Factor Gene in Streptomyces coelicolor M145 Using CRISPR/Cas9-CodA(sm) Combined System., Hu Zeng, Shishi Wen, Wei Xu, Zhaoren He, Guifa Zhai, Yunkun Liu, Zixin Deng, and Yuhui Sun., 2015
- Cross-Module Enoylreduction in the Azalomycin F Polyketide Synthase., Guifa Zhai, Wenyan Wang, Wei Xu, Guo Sun, Chaoqun Hu, Xiangming Wu, Zisong Cong, et al., 2020
- Functional Analysis of Cytochrome P450s Involved in Streptovaricin Biosynthesis and Generation of Anti-MRSA Analogues., Yuanzhen Liu, Xu Chen, Zhengyuan Li, Wei Xu, Weixin Tao, Jie Wu, Jian Yang, Zixin Deng, and Yuhui Sun., 2017
- Characterization of Biosynthetic Genes of Ascamycin/Dealanylascamycin Featuring a 5′-O-Sulfonamide Moiety in Streptomyces sp. JCM9888., Chunhua Zhao, Jianzhao Qi, Weixing Tao, Lei He, Wei Xu, Jason Chan, and Zixin Deng., 2014
- Base Editing in Streptomyces with Cas9-deaminase Fusions., Zhiyu Zhong, Junhong Guo, Liang Deng, Li Chen, Jian Wang, Sicong Li, Wei Xu, Zixin Deng, and Yuhui Sun., 2019
