Areas of Focus
- 微生物基因编辑技术的开发与应用
- 微生物来源天然产物生物合成途径的挖掘与解析
Work Experience
- 2017-07至2018-12 - 武汉大学 - 研究助理
- 2019-02至2020-04 - 新加坡科技研究局 - 科学家I
- 2020-04至2022-01 - 新加坡科技研究局 - 科学家I
- 2022-02至今 - 华中农业大学 - 副研究员
Academic Background & Achievements
- 2007-09 至 2011-06 药学学士: 武汉大学
- 2011-09 至 2017-06 生物化学与分子生物学博士: 武汉大学
Publications
- An Iterative Module in the Azalomycin F Polyketide Synthase Contains a Switchable Enoylreductase Domain., Wei Xu, Guifa Zhai, Yuanzhen Liu, Yuan Li, Yanrong Shi, Kui Hong, Hui Hong, Peter F. Leadlay, Zixin Deng, and Yuhui Sun., 2017
- Emerging Molecular Biology Tools and Strategies for Engineering Natural Product Biosynthesis., Wei Xu, Evaldas Klumbys, Ee Lui Ang, and Huimin Zhao., 2020
- Nitrilase Superfamily Aryl Acylamidase from the Halotolerant Mangrove Streptomyces Sp. 211726., Yanling Ma, Wei Xu, Jun Zhang, Sihong Zhang, Kui Hong, Zixin Deng, and Yuhui Sun., 2014
- Highly Efficient Editing of the Actinorhodin Polyketide Chain Length Factor Gene in Streptomyces coelicolor M145 Using CRISPR/Cas9-CodA(sm) Combined System., Hu Zeng, Shishi Wen, Wei Xu, Zhaoren He, Guifa Zhai, Yunkun Liu, Zixin Deng, and Yuhui Sun., 2015
- Cross-Module Enoylreduction in the Azalomycin F Polyketide Synthase., Guifa Zhai, Wenyan Wang, Wei Xu, Guo Sun, Chaoqun Hu, Xiangming Wu, Zisong Cong, et al., 2020
- Functional Analysis of Cytochrome P450s Involved in Streptovaricin Biosynthesis and Generation of Anti-MRSA Analogues., Yuanzhen Liu, Xu Chen, Zhengyuan Li, Wei Xu, Weixin Tao, Jie Wu, Jian Yang, Zixin Deng, and Yuhui Sun., 2017
- Characterization of Biosynthetic Genes of Ascamycin/Dealanylascamycin Featuring a 5′-O-Sulfonamide Moiety in Streptomyces sp. JCM9888., Chunhua Zhao, Jianzhao Qi, Weixing Tao, Lei He, Wei Xu, Jason Chan, and Zixin Deng., 2014
- Base Editing in Streptomyces with Cas9-deaminase Fusions., Zhiyu Zhong, Junhong Guo, Liang Deng, Li Chen, Jian Wang, Sicong Li, Wei Xu, Zixin Deng, and Yuhui Sun., 2019