Professor | Li Cai | Asia Growth Partners

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Name	Li Cai
Contact Information	licai@mailsysu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Li Cai

Contact Information

licai@mailsysu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	2009 - Bachelor's Degree: Huazhong University of Science and Technology 2015 - PhD: University of Copenhagen Published in journals like Science, Nature Machine Intelligence, Nature Communications
Work Experience	2019 - Present - Sun Yat-sen University - Established independent research group Postdoctoral work at Francis Crick Institute Project leader at BGI

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

2009 - Bachelor's Degree: Huazhong University of Science and Technology
2015 - PhD: University of Copenhagen
Published in journals like Science, Nature Machine Intelligence, Nature Communications

Work Experience

2019 - Present - Sun Yat-sen University - Established independent research group
Postdoctoral work at Francis Crick Institute
Project leader at BGI

Areas of Focus	Integration of multi-omics data to study genome regulation and evolution Distribution and molecular mechanisms of DNA mutations Origin and evolution of genomic regulatory elements Impact of molecular mechanisms of genome regulation and evolution on biodiversity or human diseases
Publications	A generalizable deep learning framework for inferring fine-scale germline mutation rate maps., Fang Y, Deng S, Li C#, 2022 High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts., Chia M, Li C, Marques S, Pelechano V, Luscombe NM, van Werven FJ, 2021 Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome., Li C#, Luscombe NM, 2020 Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome., Li C#, Lenhard B, Luscombe NM, 2018 Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features., Seki R, Li C, Fang Q, Hayashi S, Egawa S, Hu J, et al., 2017 Comparative genomics reveals insights into avian genome evolution and adaptation., Zhang G, Li C, Li Q, Li B, Larkin DM, Lee C, et al., 2014 Molecular traces of alternative social organization in a termite genome., Terrapon N, Li C, Robertson HM, Ji L, Meng X, Booth W, et al., 2014 Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment., Li C, Zhang Y, Li J, Kong L, Hu H, Pan H, et al., 2014 The draft genome of a socially polymorphic halictid bee, Lasioglossum albipes., Kocher SD, Li C, Yang W, Tan H, Yi SV, Yang X, et al., 2013 Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques., Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, et al., 2011 The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming., Nygaard S, Zhang G, Schiøtt M, Li C, Wurm Y, Hu H, et al., 2011

Areas of Focus

Integration of multi-omics data to study genome regulation and evolution
Distribution and molecular mechanisms of DNA mutations
Origin and evolution of genomic regulatory elements
Impact of molecular mechanisms of genome regulation and evolution on biodiversity or human diseases

Publications

A generalizable deep learning framework for inferring fine-scale germline mutation rate maps., Fang Y*, Deng S*, Li C#, 2022
High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts., Chia M*, Li C*, Marques S, Pelechano V, Luscombe NM, van Werven FJ, 2021
Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome., Li C#, Luscombe NM, 2020
Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome., Li C#, Lenhard B, Luscombe NM, 2018
Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features., Seki R*, Li C*, Fang Q, Hayashi S, Egawa S, Hu J, et al., 2017
Comparative genomics reveals insights into avian genome evolution and adaptation., Zhang G*, Li C*, Li Q, Li B, Larkin DM, Lee C, et al., 2014
Molecular traces of alternative social organization in a termite genome., Terrapon N*, Li C*, Robertson HM, Ji L, Meng X, Booth W, et al., 2014
Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment., Li C*, Zhang Y*, Li J*, Kong L*, Hu H, Pan H, et al., 2014
The draft genome of a socially polymorphic halictid bee, Lasioglossum albipes., Kocher SD*, Li C*, Yang W, Tan H, Yi SV, Yang X, et al., 2013
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques., Yan G*, Zhang G*, Fang X*, Zhang Y*, Li C*, Ling F*, et al., 2011
The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming., Nygaard S*, Zhang G*, Schiøtt M*, Li C*, Wurm Y, Hu H, et al., 2011

Genomics Bioinformatics Evolution Dna Mutations Regulatory Elements Biodiversity Human Diseases Multi-Omics Genome Regulation Molecular Mechanisms

Kai Li - East China Normal University

Wei Mei Jiang - Zhejiang University

Yunfa Ge - Zhejiang University

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