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李彩
Life Science
中山大学
广东
Language: 英语, 中文
基因组学
生物信息学
进化
Dna突变
调控元件
生物多样性
人类疾病
多组学
基因组调控
分子机制
Areas of Focus
- 整合多组学数据研究基因组调控与演化
- DNA突变的分布及分子机制
- 基因组调控元件的起源及演化
- 基因组调控及演化的分子机制对生物多样性或人类疾病的影响
Work Experience
- 2019 - 现在 - 中山大学 - 建立独立课题组
- 在弗朗西斯·克里克研究所进行博士后工作
- 在华大基因研究院担任项目组长
Academic Background & Achievements
- 2009 - 学士学位: 华中科技大学
- 2015 - 博士学位: 哥本哈根大学
- 在Science、Nature Machine Intelligence、Nature Communications等期刊发表论文
Publications
- A generalizable deep learning framework for inferring fine-scale germline mutation rate maps., Fang Y*, Deng S*, Li C#, 2022
- High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts., Chia M*, Li C*, Marques S, Pelechano V, Luscombe NM, van Werven FJ, 2021
- Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome., Li C#, Luscombe NM, 2020
- Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome., Li C#, Lenhard B, Luscombe NM, 2018
- Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features., Seki R*, Li C*, Fang Q, Hayashi S, Egawa S, Hu J, et al., 2017
- Comparative genomics reveals insights into avian genome evolution and adaptation., Zhang G*, Li C*, Li Q, Li B, Larkin DM, Lee C, et al., 2014
- Molecular traces of alternative social organization in a termite genome., Terrapon N*, Li C*, Robertson HM, Ji L, Meng X, Booth W, et al., 2014
- Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment., Li C*, Zhang Y*, Li J*, Kong L*, Hu H, Pan H, et al., 2014
- The draft genome of a socially polymorphic halictid bee, Lasioglossum albipes., Kocher SD*, Li C*, Yang W, Tan H, Yi SV, Yang X, et al., 2013
- Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques., Yan G*, Zhang G*, Fang X*, Zhang Y*, Li C*, Ling F*, et al., 2011
- The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming., Nygaard S*, Zhang G*, Schiøtt M*, Li C*, Wurm Y, Hu H, et al., 2011
