1998/9-2002/7 Bachelor: Southwest Agricultural University
2003/9-2008/7 Doctorate: Sun Yat-sen University
National Outstanding Youth Science Fund recipient
2008/7-2010/12 - Sun Yat-sen University - Lecturer
2011/1-2015/12 - Sun Yat-sen University - Associate Professor
2016/1-present - Sun Yat-sen University - Professor
2022: National Outstanding Youth Science Fund
Research
Development of new high-throughput sequencing technologies Identification of non-coding RNA and RNA modifications Mechanisms of non-coding RNA and RNA modifications in disease
RIP-PEN-seq identifies a class of kink-turn RNAs as splicing regulators., Li B+, Liu S+, Zheng W+, Liu A+, Yu P+, Wu D, Zhou J, Zhang P, Liu C, Lin Q, Ye J, He S, Huang Q, Zhou H, Chen J, Qu L*, Yang J*., 2023
RNA-Guided RNA Modifications: Biogenesis, Functions, and Applications., Li B, Qu L*, Yang J*., 2023
TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation., Xu W+, Liu C+, Deng B+, Lin P+, Sun Z, Liu A, Xuan J, Li Y, Zhou K, Zhang X, Huang Q, Zhou H, He Q, Li B*, Qu L*, Yang J*., 2022
Single-base resolution mapping of 2'-O-methylation sites by an exoribonuclease-enriched chemical method., Zhang P+, Huang J+, Zheng W, Chen L, Liu S, Liu A, Ye J, Zhou J, Chen Z, Huang Q, Liu S, Zhou K, Qu L*, Li B*, Yang J*., 2023
RMBase v3.0: decode the landscape, mechanisms and functions of RNA modifications., Xuan J*, Chen L, Chen Z, Pang J, Huang J, Lin J, Zheng L, Li B*, Qu L*, Yang J*., 2023
Classification and function of RNA-protein interactions., Liu S, Li B, Liang Q, Liu A, Qu L*, Yang J*., 2020
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally., Huang H+, Weng H+, Zhou K+, Wu T+, Zhao B. S+, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, Zhou Y, Qin H, Tao S, Du J, Liu J, Lu Z, Yin H, Mesquita A, Yuan C. L, Hu Y.-C, Sun W, Su R, Dong L, Shen C, Li C, Qing Y, Jiang X, Wu X, Sun M, Guan J.-L, Qu L, Wei M, Müschen M, Huang G*, He C*, Yang J*, Chen J*., 2019
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination., Deng B+, Xu W+, Wang Z, Liu C, Lin P, Li B, Huang Q, Yang J*, Zhou H*, Qu L*., 2019
Recognition of RNA N(6)-methyladenosine by IGF2BP proteins enhances mRNA stability and translation., Huang H+, Weng H+, Sun W+, Qin X+, Shi H+, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, Hüttelmaier S, Skibbe JR, Su R, Deng X, Dong L, Sun M, Li C, Nachtergaele S, Wang Y, Hu C, Ferchen K, Greis KD, Jiang X, Wei M, Qu L, Guan JL, He C*, Yang J*, Chen J*., 2018
Prognostic Value of a Long Non-coding RNA Signature in Localized Clear Cell Renal Cell Carcinoma., Qu L+, Wang ZL+, Chen Q+, Li YM+, He HW, Hsieh JJ, Xue S, Wu ZJ, Liu B, Tang H, Xu XF, Xu F, Wang J, Bao Y, Wang AB, Wang D, Yi XM, Zhou ZK, Shi CJ, Zhong K, Sheng ZC, Zhou YL, Jiang J, Chu XY, He J, Ge JP, Zhang ZY, Zhou WQ*, Chen C*, Yang JH*, Sun YH*, Wang LH*., 2018
Capturing the interactome of newly transcribed RNA., Bao X, Guo X, Yin M, Tariq M, Lai Y, Kanwal S, Zhou J, Li N, Lv Y, Pulido-Quetglas C, Wang X, Ji L, Khan MJ, Zhu X, Luo Z, Shao C, Lim DH, Liu X, Li N, Wang W, He M, Liu YL, Ward C, Wang T, Zhang G, Wang D, Yang J, Chen Y, Zhang C, Jauch R, Yang YG, Wang Y, Qin B, Anko ML, Hutchins AP, Sun H, Wang H, Fu XD, Zhang B, Esteban MA., 2018
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification., Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, Yang J, Qian Z, Wei M, He C, Chen J., 2018
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers., Wang ZL+, Li B+, Luo YX, Lin Q, Liu SR, Zhang XQ, Zhou H, Yang JH*#, Qu LH*., 2018
dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease., Zheng LL+, Zhou KR+, Liu S, Zhang DY, Wang ZL, Chen ZR, Yang JH*, Qu LH*., 2018
RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data., Xuan JJ, Sun WJ, Lin PH, Zhou KR, Liu S, Zheng LL, Qu LH*, Yang JH*., 2018
Spatial-temporal transcriptional dynamics of long non-coding RNAs in human brain., Zhang XQ*+, Wang ZL+, Poon MW+, Yang JH*., 2017
Exo-miRExplorer: A Comprehensive Resource for Exploring and Comparatively Analyzing Exogenous MicroRNAs., Zheng LL, Deng KW, Deng AC, Wu J, Yang JH, Lun ZR, Qu LH., 2017
ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data., Zhou KR, Liu S, Sun WJ, Zheng LL, Zhou H, Yang JH*, Qu LH*., 2017
Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy., Huang ZP, Ding Y, Chen J, Wu G, Kataoka M, Hu Y, Yang JH, Liu J, Drakos SG, Selzman CH, Kyselovic J, Qu LH, Dos Remedios CG, Pu WT, Wang DZ., 2016
Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling., Guo YH, Wang LQ, Li B, Xu H, Yang JH, Zheng LS, Yu P, Zhou AD, Zhang Y, Xie SJ, Liang ZR, Zhang CM, Zhou H, Qu LH., 2016
tRF2Cancer: A web server to detect tRNA-derived small RNA fragments (tRFs) and their expression in multiple cancers., Zheng LL, Xu WL, Liu S, Sun WJ, Li JH, Wu J, Yang JH*, Qu LH*., 2016
Integrative analysis reveals clinical phenotypes and oncogenic potentials of long non-coding RNAs across 15 cancer types., Wang ZL+, Li B,+ Piccolo SR, Zhang XQ, Li JH, Zhou H, Yang JH*, Qu LH*., 2016
deepBase v2.0: identification, expression, evolution and function of small RNAs, LncRNAs and circular RNAs from deep-sequencing data., Zheng LL, Li JH, Wu J, Sun WJ, Liu S, Wang ZL, Zhou H, Yang JH*, Qu LH*., 2016
RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data., Sun WJ, Li JH, Liu S, Wu J, Zhou H, Qu LH*, Yang JH*., 2016
StarScan: a web server for scanning small RNA targets from degradome sequencing data., Liu S, Li JH, Wu J, Zhou KR, Zhou H, Yang JH*, Qu LH*., 2015
Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Li JH, Liu S, Zheng LL, Wu J, Sun WJ, Wang ZL, Zhou H, Qu LH*, Yang JH*., 2015
Rapid birth-and-death evolution of imprinted snoRNAs in the Prader-Willi syndrome locus: implications for neural development in Euarchontoglires., Zhang YJ, Yang JH, Shi QS, Zheng LL, Liu J, Zhou H, Zhang H, Qu LH., 2014
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis., Gou LT+, Dai P+, Yang JH+, Xue Y, Hu YP, Zhou Y, Kang JY, Wang X, Li H, Hua MM, Zhao S, Hu SD, Wu LG, Shi HJ, Li Y, Fu XD, Qu LH, Wang ED, Liu MF., 2014
A contig-based strategy for the genome-wide discovery of microRNAs without complete genome resources., Wen JZ, Liao JY, Zheng LL, Xu H, Yang JH, Guan DG, Zhang SM, Zhou H, Qu LH., 2014
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data., Li JH, Liu S, Zhou H, Qu LH*, Yang JH*., 2014
A Contig-Based Strategy for the Genome-Wide Discovery of MicroRNAs without Complete Genome Resources., Wen JZ, Liao JY, Zheng LL, Xu H, Yang JH, Guan DG, Zhang SM, Zhou H, Qu LH., 2014
ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data., Yang JH, Li JH, Jiang S, Zhou H, Qu LH., 2013
Deciphering the transcriptional regulation of microRNA genes in humans with ACTLocater., Xiao ZD, Diao LT, Yang JH, Xu H, Huang MB, Deng YJ, Zhou H, Qu LH., 2013
Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei., Zheng LL, Wen YZ, Yang JH, Liao JY, Shao P, Xu H, Zhou H, Wen JZ, Lun ZR, Ayala FJ, Qu LH., 2013
Drastic expression change of transposon-derived piRNA-like RNAs and microRNAs in early stages of chicken embryos implies a role in gastrulation., Shao P, Liao JY, Guan DG, Yang JH, Zheng LL, Jing Q, Zhou H, Qu LH., 2012
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data., Yang JH, Li JH, Shao P, Zhou H, Chen YQ, Qu LH., 2011
deepBase: a database for deeply annotating and mining deep sequencing data., Yang JH, Shao P, Zhou H, Chen YQ, Qu LH., 2010
ncRNAimprint: a comprehensive database of mammalian imprinted noncoding RNAs., Zhang Y, Guan DG, Yang JH, Shao P, Zhou H, Qu LH., 2010
Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach., Zhang H+, Yang JH+, Zheng YS+, Zhang P, Chen X, Wu J, Xu L, Luo XQ, Ke ZY, Zhou H, Qu LH, Chen YQ., 2009
Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs., Shao P+, Yang JH+, Zhou H, Guan DG, Qu LH., 2009
snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome., Yang JH, Zhang XC, Huang ZP, Zhou H, Huang MB, Zhang S, Chen YQ, Qu LH., 2006
Keywords
Rna-SeqHigh-ThroughputSequencingNon-Coding RnaRna ModificationsBioinformaticsDisease MechanismsProtein InteractionsRna BiologyRna Medicine
