Professor | Yan Zhang | Asia Growth Partners

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Name	Yan Zhang
Contact Information	zhang39@mail.sysu.edu.cn
Language ability	Chinese, English, Japanese
Province	Guangdong

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Name

Yan Zhang

Contact Information

zhang39@mail.sysu.edu.cn

Language ability

Chinese, English, Japanese

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	1990 - Bachelor's Degree in Medicine: Harbin Medical University 1993 - Master's Degree in Medicine: Harbin Medical University 2000 - Doctorate in Dentistry: Hiroshima University Achievement: Developed the 'MINE' concept for innovative talent cultivation in biology
Work Experience	1998-2000 - Japan Society for the Promotion of Science - Special Researcher 2000-2007 - Hiroshima University - Assistant Professor Current - Sun Yat-sen University - Professor and Doctoral Supervisor
Awards	2019: Guangdong Province Higher Education Teaching Achievement Award, First Prize 2018: National Higher Education Teaching Achievement Award, Second Prize 2020: National 'Basic Discipline Top-notch Student Training Program' Excellent Mentor Award 2019: National Life Sciences Microlecture Competition, First Prize 2019: Excellent Paper Award in Biology Teaching Research Journal

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

1990 - Bachelor's Degree in Medicine: Harbin Medical University
1993 - Master's Degree in Medicine: Harbin Medical University
2000 - Doctorate in Dentistry: Hiroshima University
Achievement: Developed the 'MINE' concept for innovative talent cultivation in biology

Work Experience

1998-2000 - Japan Society for the Promotion of Science - Special Researcher
2000-2007 - Hiroshima University - Assistant Professor
Current - Sun Yat-sen University - Professor and Doctoral Supervisor

Awards

2019: Guangdong Province Higher Education Teaching Achievement Award, First Prize
2018: National Higher Education Teaching Achievement Award, Second Prize
2020: National 'Basic Discipline Top-notch Student Training Program' Excellent Mentor Award
2019: National Life Sciences Microlecture Competition, First Prize
2019: Excellent Paper Award in Biology Teaching Research Journal

Areas of Focus	Role of cancer stem cells in tumor development Induced differentiation of pluripotent stem cells Screening and application of non-antibody binding proteins
Publications	Vascular Niche Facilitates Acquired Drug Resistance to c-Met Inhibitor in Originally Sensitive Osteosarcoma Cells, Tang WF, Zhang Y, Zhang H, Zhang Y, 2022 The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma Cells, Tian BR, Du XY, Zheng SY, Zhang Y, 2022 Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis, Lin WF, Lu XW, Yang H, Huang LX, Huang WH, Tang YL, Liu ST, Wang H, Zhang Y, 2022 Effects of biomechanical forces on the biological behavior of cancer stem cells, Tian BR, Lin WF, Zhang Y, 2021 Identification of a peptide targeting CD56, Huang HX, Liu Y, Ouyang XM, Wang H, Zhang Y, 2020 Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation, Pan, YB, Zhang Y, Tang WF, Zhang Y, 2020 Establishment of Long-Term Serum-Free Culture for Lacrimal Gland Stem Cells Aiming at Lacrimal Gland Repair, Xiao S, Zhang Y, 2020 A novel approach for T7 bacteriophage genome integration of exogenous DNA, Liu Y, Huang H, Wang H, Zhang Y, 2020 New cell-penetrating peptide (KRP) with multiple physicochemical properties endows doxorubicin with tumor targeting and improves it therapeutic index, Yu M, Li XL, Huang XF, Zhang J, Zhang Y, Wang H, 2019 Three-dimensional bone extracellular matrix model for osteosarcoma, Zhang Y, Yao YP, Zhang Y, 2019 miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-Sox2 axis, Zhang Y, Pan YB, Xie CY, Zhang Y, 2018 Fabrication of tongue extracellular matrix and reconstitution of tongue squamous cell carcinoma in vitro, Yao YP, Lin WF, Zhang Y, 2018 Stage-specific approaches promote in vitro induction for spermatogenesis, Yi HL, Xiao S, Zhang Y, 2018 Decellularized tongue tissue as an in vitro model for studying tongue cancer and tongue regeneration, Zhao L, Huang LX, Yu, Zheng JH, Wang H, Zhang Y, 2017 Identification and Characterization of Two Novel PTCH1 Splice Variants, Yu P, Yang YQ, Zhang Y, 2017 Sox2 Modulates Motility and Enhances Progression of Colorectal Cancer via the Rho-ROCK Signaling Pathway, Zheng JH, Pan YB, Yu SY, Wang HB, Derek K, and Zhang Y, 2017 Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling, Miao YY, Zhang HX, Pan YB, Ren J, Ye MM, Xia FF, Huang R, Lin ZH, Jiang S, Zhang Y, Songyang Z, Zhang Y, 2017 The lacrimal gland: development, wound repair and regeneration, Yao YP, Zhang Y, 2017 Microenvironment Signals and Mechanisms in the Regulation of Osteosarcoma, Zhang Y, Mai Q, Zhang XW, Xie CY and Zhang Y, 2017 肿瘤代谢异质性的研究进展, 麦青，张雁, 2017 Establishing primary cell cultures from Branchiostoma belcheri Japanese, Cai XQ, Wang HM, Huang LX, Chen JT, Zhang QF, Zhang Y, 2013 TGF-β1 signal is crucial for de-differentiation of cancer cells to cancer stem cells in osteosarcoma, Zhang HX, Wu HT, Zheng JH, Yu P, Xu LX, Jiang P, Gao J, Wang H and Zhang Y, 2013 N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro, Yang T, Fang S, Zhang HX, Xu LX, Zhang ZQ, Yuan KT, Xue CL, Yu HL, Zhang S, Li YF, Shi Han P* and Zhang Y*, 2013

Areas of Focus

Role of cancer stem cells in tumor development
Induced differentiation of pluripotent stem cells
Screening and application of non-antibody binding proteins

Publications

Vascular Niche Facilitates Acquired Drug Resistance to c-Met Inhibitor in Originally Sensitive Osteosarcoma Cells, Tang WF, Zhang Y, Zhang H, Zhang Y*, 2022
The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma Cells, Tian BR, Du XY, Zheng SY, Zhang Y*, 2022
Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis, Lin WF, Lu XW, Yang H, Huang LX, Huang WH, Tang YL, Liu ST, Wang H, Zhang Y*, 2022
Effects of biomechanical forces on the biological behavior of cancer stem cells, Tian BR, Lin WF, Zhang Y*, 2021
Identification of a peptide targeting CD56, Huang HX, Liu Y, Ouyang XM, Wang H*, Zhang Y*, 2020
Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation, Pan, YB, Zhang Y, Tang WF, Zhang Y*, 2020
Establishment of Long-Term Serum-Free Culture for Lacrimal Gland Stem Cells Aiming at Lacrimal Gland Repair, Xiao S, Zhang Y*, 2020
A novel approach for T7 bacteriophage genome integration of exogenous DNA, Liu Y, Huang H, Wang H, Zhang Y*, 2020
New cell-penetrating peptide (KRP) with multiple physicochemical properties endows doxorubicin with tumor targeting and improves it therapeutic index, Yu M, Li XL, Huang XF, Zhang J, Zhang Y, Wang H*, 2019
Three-dimensional bone extracellular matrix model for osteosarcoma, Zhang Y, Yao YP, Zhang Y*, 2019
miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-Sox2 axis, Zhang Y, Pan YB, Xie CY, Zhang Y*, 2018
Fabrication of tongue extracellular matrix and reconstitution of tongue squamous cell carcinoma in vitro, Yao YP, Lin WF, Zhang Y*, 2018
Stage-specific approaches promote in vitro induction for spermatogenesis, Yi HL, Xiao S, Zhang Y*, 2018
Decellularized tongue tissue as an in vitro model for studying tongue cancer and tongue regeneration, Zhao L, Huang LX, Yu, Zheng JH, Wang H, Zhang Y*, 2017
Identification and Characterization of Two Novel PTCH1 Splice Variants, Yu P, Yang YQ, Zhang Y*, 2017
Sox2 Modulates Motility and Enhances Progression of Colorectal Cancer via the Rho-ROCK Signaling Pathway, Zheng JH, Pan YB, Yu SY, Wang HB, Derek K, and Zhang Y*, 2017
Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling, Miao YY, Zhang HX, Pan YB, Ren J, Ye MM, Xia FF, Huang R, Lin ZH, Jiang S, Zhang Y, Songyang Z*, Zhang Y*, 2017
The lacrimal gland: development, wound repair and regeneration, Yao YP, Zhang Y*, 2017
Microenvironment Signals and Mechanisms in the Regulation of Osteosarcoma, Zhang Y, Mai Q, Zhang XW, Xie CY and Zhang Y*, 2017
肿瘤代谢异质性的研究进展, 麦青，张雁*, 2017
Establishing primary cell cultures from Branchiostoma belcheri Japanese, Cai XQ, Wang HM, Huang LX, Chen JT, Zhang QF, Zhang Y*, 2013
TGF-β1 signal is crucial for de-differentiation of cancer cells to cancer stem cells in osteosarcoma, Zhang HX, Wu HT, Zheng JH, Yu P, Xu LX, Jiang P, Gao J, Wang H and Zhang Y*, 2013
N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro, Yang T, Fang S, Zhang HX, Xu LX, Zhang ZQ, Yuan KT, Xue CL, Yu HL, Zhang S, Li YF, Shi Han P* and Zhang Y*, 2013

Cancer Stem Cells Tumor Development Microenvironment Cell Reprogramming Pluripotent Stem Cells Differentiation Molecular Regulation Non-Antibody Proteins Screening Application

Yu Fei Ma - Xi'an Jiaotong University

Xiyun Yan - University of Chinese Academy of Sciences

Mingqiu Liu - Fudan University

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