Professor | 张雁 | 数字化转型顾问

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Name	张雁
Contact Information	zhang39@mail.sysu.edu.cn
Language ability	中文, 英语, 日语
Province	广东

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Name

张雁

Contact Information

zhang39@mail.sysu.edu.cn

Language ability

中文, 英语, 日语

Province

广东

University/Lab Affiliation and Title	中山大学
Faculty	Life Sciences
Academic Background & Achievements	1990年 - 医学学士学位: 哈尔滨医科大学 1993年 - 医学硕士学位: 哈尔滨医科大学 2000年 - 齿学博士学位: 日本广岛大学成就: 提出了生物学创新性人才培养的“MINE”理念
Work Experience	1998-2000 - 日本学术振兴会 - 特别研究员 2000-2007 - 广岛大学 - 助理教授现任 - 中山大学 - 教授和博士生导师
Awards	2019年: 广东省高等教育教学成果奖一等奖 2018年: 国家高等教育教学成果奖二等奖 2020年: 国家“基础学科拔尖学生培养计划”优秀导师奖 2019年: 全国生命科学微课比赛一等奖 2019年: 生物学教学研究期刊优秀论文奖

University/Lab Affiliation and Title

中山大学

Faculty

Life Sciences

Academic Background & Achievements

1990年 - 医学学士学位: 哈尔滨医科大学
1993年 - 医学硕士学位: 哈尔滨医科大学
2000年 - 齿学博士学位: 日本广岛大学
成就: 提出了生物学创新性人才培养的“MINE”理念

Work Experience

1998-2000 - 日本学术振兴会 - 特别研究员
2000-2007 - 广岛大学 - 助理教授
现任 - 中山大学 - 教授和博士生导师

Awards

2019年: 广东省高等教育教学成果奖一等奖
2018年: 国家高等教育教学成果奖二等奖
2020年: 国家“基础学科拔尖学生培养计划”优秀导师奖
2019年: 全国生命科学微课比赛一等奖
2019年: 生物学教学研究期刊优秀论文奖

Areas of Focus	肿瘤干细胞在肿瘤发展中的作用多能干细胞的诱导分化非抗体结合蛋白的筛选及应用
Publications	Vascular Niche Facilitates Acquired Drug Resistance to c-Met Inhibitor in Originally Sensitive Osteosarcoma Cells, Tang WF, Zhang Y, Zhang H, Zhang Y, 2022 The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma Cells, Tian BR, Du XY, Zheng SY, Zhang Y, 2022 Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis, Lin WF, Lu XW, Yang H, Huang LX, Huang WH, Tang YL, Liu ST, Wang H, Zhang Y, 2022 Effects of biomechanical forces on the biological behavior of cancer stem cells, Tian BR, Lin WF, Zhang Y, 2021 Identification of a peptide targeting CD56, Huang HX, Liu Y, Ouyang XM, Wang H, Zhang Y, 2020 Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation, Pan, YB, Zhang Y, Tang WF, Zhang Y, 2020 Establishment of Long-Term Serum-Free Culture for Lacrimal Gland Stem Cells Aiming at Lacrimal Gland Repair, Xiao S, Zhang Y, 2020 A novel approach for T7 bacteriophage genome integration of exogenous DNA, Liu Y, Huang H, Wang H, Zhang Y, 2020 New cell-penetrating peptide (KRP) with multiple physicochemical properties endows doxorubicin with tumor targeting and improves it therapeutic index, Yu M, Li XL, Huang XF, Zhang J, Zhang Y, Wang H, 2019 Three-dimensional bone extracellular matrix model for osteosarcoma, Zhang Y, Yao YP, Zhang Y, 2019 miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-Sox2 axis, Zhang Y, Pan YB, Xie CY, Zhang Y, 2018 Fabrication of tongue extracellular matrix and reconstitution of tongue squamous cell carcinoma in vitro, Yao YP, Lin WF, Zhang Y, 2018 Stage-specific approaches promote in vitro induction for spermatogenesis, Yi HL, Xiao S, Zhang Y, 2018 Decellularized tongue tissue as an in vitro model for studying tongue cancer and tongue regeneration, Zhao L, Huang LX, Yu, Zheng JH, Wang H, Zhang Y, 2017 Identification and Characterization of Two Novel PTCH1 Splice Variants, Yu P, Yang YQ, Zhang Y, 2017 Sox2 Modulates Motility and Enhances Progression of Colorectal Cancer via the Rho-ROCK Signaling Pathway, Zheng JH, Pan YB, Yu SY, Wang HB, Derek K, and Zhang Y, 2017 Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling, Miao YY, Zhang HX, Pan YB, Ren J, Ye MM, Xia FF, Huang R, Lin ZH, Jiang S, Zhang Y, Songyang Z, Zhang Y, 2017 The lacrimal gland: development, wound repair and regeneration, Yao YP, Zhang Y, 2017 Microenvironment Signals and Mechanisms in the Regulation of Osteosarcoma, Zhang Y, Mai Q, Zhang XW, Xie CY and Zhang Y, 2017 肿瘤代谢异质性的研究进展, 麦青，张雁, 2017 Establishing primary cell cultures from Branchiostoma belcheri Japanese, Cai XQ, Wang HM, Huang LX, Chen JT, Zhang QF, Zhang Y, 2013 TGF-β1 signal is crucial for de-differentiation of cancer cells to cancer stem cells in osteosarcoma, Zhang HX, Wu HT, Zheng JH, Yu P, Xu LX, Jiang P, Gao J, Wang H and Zhang Y, 2013 N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro, Yang T, Fang S, Zhang HX, Xu LX, Zhang ZQ, Yuan KT, Xue CL, Yu HL, Zhang S, Li YF, Shi Han P* and Zhang Y*, 2013

Areas of Focus

肿瘤干细胞在肿瘤发展中的作用
多能干细胞的诱导分化
非抗体结合蛋白的筛选及应用

Publications

Vascular Niche Facilitates Acquired Drug Resistance to c-Met Inhibitor in Originally Sensitive Osteosarcoma Cells, Tang WF, Zhang Y, Zhang H, Zhang Y*, 2022
The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma Cells, Tian BR, Du XY, Zheng SY, Zhang Y*, 2022
Metabolic heterogeneity protects metastatic mucosal melanomas cells from ferroptosis, Lin WF, Lu XW, Yang H, Huang LX, Huang WH, Tang YL, Liu ST, Wang H, Zhang Y*, 2022
Effects of biomechanical forces on the biological behavior of cancer stem cells, Tian BR, Lin WF, Zhang Y*, 2021
Identification of a peptide targeting CD56, Huang HX, Liu Y, Ouyang XM, Wang H*, Zhang Y*, 2020
Interstitial serum albumin empowers osteosarcoma cells with FAIM2 transcription to obtain viability via dedifferentiation, Pan, YB, Zhang Y, Tang WF, Zhang Y*, 2020
Establishment of Long-Term Serum-Free Culture for Lacrimal Gland Stem Cells Aiming at Lacrimal Gland Repair, Xiao S, Zhang Y*, 2020
A novel approach for T7 bacteriophage genome integration of exogenous DNA, Liu Y, Huang H, Wang H, Zhang Y*, 2020
New cell-penetrating peptide (KRP) with multiple physicochemical properties endows doxorubicin with tumor targeting and improves it therapeutic index, Yu M, Li XL, Huang XF, Zhang J, Zhang Y, Wang H*, 2019
Three-dimensional bone extracellular matrix model for osteosarcoma, Zhang Y, Yao YP, Zhang Y*, 2019
miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-Sox2 axis, Zhang Y, Pan YB, Xie CY, Zhang Y*, 2018
Fabrication of tongue extracellular matrix and reconstitution of tongue squamous cell carcinoma in vitro, Yao YP, Lin WF, Zhang Y*, 2018
Stage-specific approaches promote in vitro induction for spermatogenesis, Yi HL, Xiao S, Zhang Y*, 2018
Decellularized tongue tissue as an in vitro model for studying tongue cancer and tongue regeneration, Zhao L, Huang LX, Yu, Zheng JH, Wang H, Zhang Y*, 2017
Identification and Characterization of Two Novel PTCH1 Splice Variants, Yu P, Yang YQ, Zhang Y*, 2017
Sox2 Modulates Motility and Enhances Progression of Colorectal Cancer via the Rho-ROCK Signaling Pathway, Zheng JH, Pan YB, Yu SY, Wang HB, Derek K, and Zhang Y*, 2017
Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling, Miao YY, Zhang HX, Pan YB, Ren J, Ye MM, Xia FF, Huang R, Lin ZH, Jiang S, Zhang Y, Songyang Z*, Zhang Y*, 2017
The lacrimal gland: development, wound repair and regeneration, Yao YP, Zhang Y*, 2017
Microenvironment Signals and Mechanisms in the Regulation of Osteosarcoma, Zhang Y, Mai Q, Zhang XW, Xie CY and Zhang Y*, 2017
肿瘤代谢异质性的研究进展, 麦青，张雁*, 2017
Establishing primary cell cultures from Branchiostoma belcheri Japanese, Cai XQ, Wang HM, Huang LX, Chen JT, Zhang QF, Zhang Y*, 2013
TGF-β1 signal is crucial for de-differentiation of cancer cells to cancer stem cells in osteosarcoma, Zhang HX, Wu HT, Zheng JH, Yu P, Xu LX, Jiang P, Gao J, Wang H and Zhang Y*, 2013
N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro, Yang T, Fang S, Zhang HX, Xu LX, Zhang ZQ, Yuan KT, Xue CL, Yu HL, Zhang S, Li YF, Shi Han P* and Zhang Y*, 2013

肿瘤干细胞肿瘤发展微环境细胞重编程多能干细胞分化分子调控非抗体蛋白筛选应用

康岚 - 同济大学

陈平 - 同济大学

Area of Focus
表观遗传学 | 癌症 | 非编码Rna | 干细胞 | 分化 | 肝组织 | 机制 | 应用 | 动物模型 | 细胞治疗

张建保 - 西安交通大学

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