2009 - Doctorate: Kunming Institute of Zoology, Chinese Academy of Sciences
2015 - Selected for Sun Yat-sen University's 'Hundred Talents Program'
2015 - National Overseas High-Level Talent
2017 - Guangdong Province 'Pearl River Talent Plan' Innovation and Entrepreneurship Team Talent
2009-2011 - Research on small RNA evolution at Stephen Cohen's lab, Royal Society, London and Chung-I Wu's lab, Academia Sinica, Taiwan
2011-2015 - Postdoctoral research at Stanford University School of Medicine, Department of Genetics
Research
RNA editing, modification, and RNA therapy Gene editing for disease treatment
Epitranscriptomic subtyping, visualization, and denoising by global motif visualization, Jianheng Liu, Tao Huang, Jing Yao, Tianxuan Zhao, Yusen Zhang, Rui Zhang, 2023
Patients with Asian-type DEL can safely be transfused using RhD-positive blood, Yanli Ji, Yalin Luo, Jizhi Wen, Yuanfan Sun, Shuangshuang Jia, Chunquan Ou, Wenbing Yang, Jingwang Chen, Hanshen Ye, Xiangfu Liu, Yongneng Liang, Zhigang Lu, Ying Feng, Xinzhong Wu, Muzhou Xiao, Jiankun Mo, Zhenhai Zhou, Zhen Wang, Zhijian Liao, Junhu Chen, Ling Wei, Guangping Luo, Sentot Santoso, Yann Fichou, Willy Albert Flegel, Chaopeng Shao, Chengyao Li, Rui Zhang, Yongshui Fu, 2023
Developmental mRNA m5C landscape and regulatory innovations of massive m5C modification of maternal mRNAs in animals, Jianheng Liu, Tao Huang, Wanying Chen, Chenhui Ding, Tianxuan Zhao, Xueni Zhao, Bing Cai, Yusen Zhang, Song Li, Ling Zhang, Maoguang Xue, Xiuju He, Wanzhong Ge, Canquan Zhou, Yanwen Xu, Rui Zhang, 2022
Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution, Yulong Song, Xiuju He, Wenbing Yang, Yaoxing Wu, Jun Cui, Tian Tang, Rui Zhang, 2022
Sequence- and structure-selective mRNA m5C methylation by NSUN6 in animals, Jianheng Liu, Tao Huang, Yusen Zhang, Tianxuan Zhao, Xueni Zhao, Wanying Chen, Rui Zhang, 2021
Human A-to-I RNA editing SNP loci are enriched in GWAS signals for autoimmune diseases and under balancing selection, Hui Zhang, Qiang Fu, Xinrui Shi, Ziqing Pan, Wenbing Yang, Zichao Huang, Tian Tang, Xionglei He, Rui Zhang, 2020
Dynamic landscape and evolution of m6A methylation in human, Hui Zhang, Xinrui Shi, Tao Huang, Wanying Chen, Nannan Gu, Rui Zhang, 2020
A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-Bisphosphatase Enables Hepatic and Renal Tumorigenesis, Kun Liao, Shuye Deng, Liyan Xu, Wenfeng Pan, Shiyu Yang, Fufu Zheng, Xingui Wu, Hongrong Hu, Zhijun Liu, Junhang Luo, Rui Zhang, Dong-Ming Kuang, Jiajun Dong, Yi Wu, Hui Zhang, Penghui Zhou, Jin-Xin Bei, Yang Xu, Yin Ji, Peng Wang, Huai-Qiang Ju, Rui-Hua Xu, Bo Li, 2020
Genome-wide identification of mRNA 5-methylcytosine in mammals, Tao Huang, Wanying Chen, Jianheng Liu, Nannan Gu, Rui Zhang, 2019
The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting, Lishi Li, Yulong Song, Xinrui Shi, Jianheng Liu, Shaolei Xiong, Wanying Chen, Qiang Fu, Zichao Huang, Nannan Gu, Rui Zhang, 2018
Evolutionary analysis reveals regulatory and functional landscape of coding and non-coding RNA editing, Rui Zhang, Patricia Deng, Dionna Jacobson, Jin Billy Li, 2017
Dynamic landscape and regulation of RNA editing in mammals, Meng How Tan, Qin Li, 2017
Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease, eGTEx Project, 2017
Genetic mapping uncovers cis-regulatory landscape of RNA editing, Gokul Ramaswami, Patricia Deng, Rui Zhang, Mary Anne Carbone, Trudy F.C. Mackay, Li Jin Billy, 2015
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers, Leng Han, Lixia Diao, Shuangxing Yu, Xiaoyan Xu, 2015
Effect of predicted protein-truncating genetic variants on the human transcriptome, Manuel A Rivas, 2015
The landscape of genomic imprinting across diverse adult human tissues, Yael Baran, 2015
Genetic conflict reflected in tissue-specific maps of genomic imprinting, Tomas Babak, Brian DeVeale, Emily K Tsang, Yiqi Zhou, Xin Li, Kevin S Smith, Kim R Kukurba, Rui Zhang, Jin Billy Li, Derek van der Kooy, Stephen B Montgomery and Hunter B Fraser, 2015
Cis regulatory effects on A-to-I RNA editing in related Drosophila species, Anne L. Sapiro, Patricia Deng, Rui Zhang, Jin Billy Li, 2015
Functional conservation of both CDS- and 3’-UTR-located microRNA binding sites between species, Guojing Liu, Rui Zhang, Jin Xu, Chung-I Wu and Xuemei Lu, 2014
Allelic expression of deleterious protein-coding variants across human tissues, Kimberly R. Kukurba, Rui Zhang, Xin Li, Kevin S. Smith, David A. Knowles, Meng How Tan, Robert Piskol, Monkol Lek, Michael Snyder, Daniel G. MacArthur, Jin Billy Li and Stephen B. Montgomery, 2014
Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing, Rui Zhang, Xin Li, Gokul Ramaswami, Kevin S Smith, Gustavo Turecki, Stephen B Montgomery and Jin Billy Li, 2014
Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover, Xin Hong, Hung Thanh Nguyen, Qingfeng Chen, Rui Zhang, Zandra Hagman, P Mathijs and Stephen Cohen, 2014
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes, Lily Bazak, Ami Haviv, Michal Barak, Jasmine Jacob-Hirsch, Patricia Deng, Rui Zhang, Farren J Isaacs, Gideon Rechavi, Jin Billy Li, Eli Eisenberg and Erez Y Levanon, 2013
The evolution of evolvability in microRNA target sites in vertebrates, Jin Xu, Rui Zhang, Yang Shen, Guojing Liu, Xuemei Lu and Chung-I Wu, 2013
Identifying RNA editing sites using RNA sequencing data alone, Gokul Ramaswami, Rui Zhang, Robert Piskol, Liam P Keegan, Patricia Deng, Mary A O'Connell and Jin Billy Li, 2013
Testing hypotheses on the rate of molecular evolution in relation to gene expression using microRNAs, Yang Shen, Yang Lv, Lei Huang, Wensheng Liu, Ming Wen, Tian Tang, Rui Zhang, Eric Hungate, Suhua Shi and Chung-I Wu, 2011
Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis, Wanzhong Ge, Yawen Chen, Ruifen Weng, Singfee Lim, Marita Buescher, Rui Zhang and Stephen M. Cohen, 2011
Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque, Xiaodong Fang, Yanfeng Zhang, Rui Zhang, Lixin Yang, Ming Li, Kaixiong Ye, Xiaosen Guo, Jun Wang and Bing Su, 2011
MicroRNA regulation and the variability of human cortical gene expression, Rui Zhang and Bing Su, 2008
Molecular evolution of a primate-specific microRNA family, Rui Zhang, Yinqiu Wang and Bing Su, 2008
Rapid evolution of an X-linked microRNA cluster in primates, Rui Zhang, Yi Peng, Wen Wang and Bing Su, 2007
