Professor | Chen Dongping | Asia Growth Partners

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Name	Chen Dongping
Contact Information	chendp23@mail.sysu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Chen Dongping

Contact Information

chendp23@mail.sysu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	2013/09-2018/07 PhD in Biochemistry and Molecular Biology: Sun Yat-sen University Original research on energy metabolism determining cell fate/immune microenvironment characteristics and its impact on disease progression
Work Experience	2023/02-present - Sun Yat-sen University - Associate Professor 2021/11-2023/01 - Sun Yat-sen University - Associate Researcher 2018/08-2021/11 - Sun Yat-sen University - Postdoctoral Researcher

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

2013/09-2018/07 PhD in Biochemistry and Molecular Biology: Sun Yat-sen University
Original research on energy metabolism determining cell fate/immune microenvironment characteristics and its impact on disease progression

Work Experience

2023/02-present - Sun Yat-sen University - Associate Professor
2021/11-2023/01 - Sun Yat-sen University - Associate Researcher
2018/08-2021/11 - Sun Yat-sen University - Postdoctoral Researcher

Areas of Focus	Tumor Immunity and Metabolism Myeloid Cells Inflammatory Tissue Microenvironment
Publications	Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma., Chen DP, Ning WR, Jiang ZZ, Peng ZP, Zhu LY, Zhuang SM, Kuang DM, Zheng L, Wu Y., 2019 Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma., Chen DP, Ning WR, Li XF, Wei Y, Lao XM, Wang JC, Wu Y, Zheng L., 2018 Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., Wu RQ#, Lao XM#, Chen DP#, Qin H, Mu M, Cao WJ, Deng J, Wan CC, Zhan WY, Wang JC, Xu L, Chen MS, Gao Q, Zheng L, Wei Y, Kuang DM., 2023 PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma., Wang JC#, Chen DP#, Lu SX#, Chen JB#, Wei Y#, Liu XC#, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM, Chen MS, Zhou ZG., 2022 B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis., Zeng QH#, Wei Y#, Lao XM#, Chen DP#, Huang CX, Lin QY, He M, Liao Y, Zheng L, Li B, Zhang GB, Chen Y, Kuang DM., 2020 Identification of cross-talk between m6A and 5mC regulators associated with onco-immunogenic features and prognosis across 33 cancer types., Chen YT#, Shen JY#, Chen DP#, Wu CF, Guo R, Zhang PP, Lv JW, Li WF, Wang ZX, Chen YP., 2020 Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma., Chen YP#, Yin JH#, Li WF#, Li HJ#, Chen DP#, Zhang CJ#, Lv JW, Wang YQ, Li XM, Li JY, Zhang PP, Li YQ, He QM, Yang XJ, Lei Y, Tang LL, Zhou GQ, Mao YP, Wei C, Xiong KX, Zhang HB, Zhu SD, Hou Y, Sun Y, Dean M, Amit I, Wu K, Kuang DM, Li GB, Liu N, Ma J., 2020 Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma., Li XF, Chen DP, Ouyang FZ, Chen MM, Wu Y, Kuang DM, Zheng L., 2015

Areas of Focus

Tumor Immunity and Metabolism
Myeloid Cells
Inflammatory Tissue Microenvironment

Publications

Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma., Chen DP, Ning WR, Jiang ZZ, Peng ZP, Zhu LY, Zhuang SM, Kuang DM, Zheng L*, Wu Y*., 2019
Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma., Chen DP, Ning WR, Li XF, Wei Y, Lao XM, Wang JC, Wu Y*, Zheng L*., 2018
Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., Wu RQ#, Lao XM#, Chen DP#, Qin H, Mu M, Cao WJ, Deng J, Wan CC, Zhan WY, Wang JC, Xu L, Chen MS, Gao Q, Zheng L, Wei Y*, Kuang DM*., 2023
PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma., Wang JC#, Chen DP#, Lu SX#, Chen JB#, Wei Y#, Liu XC#, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM*, Chen MS*, Zhou ZG*., 2022
B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis., Zeng QH#, Wei Y#, Lao XM#, Chen DP#, Huang CX, Lin QY, He M, Liao Y, Zheng L, Li B, Zhang GB*, Chen Y*, Kuang DM*., 2020
Identification of cross-talk between m6A and 5mC regulators associated with onco-immunogenic features and prognosis across 33 cancer types., Chen YT#, Shen JY#, Chen DP#, Wu CF, Guo R, Zhang PP, Lv JW, Li WF*, Wang ZX*, Chen YP*., 2020
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma., Chen YP#, Yin JH#, Li WF#, Li HJ#, Chen DP#, Zhang CJ#, Lv JW, Wang YQ, Li XM, Li JY, Zhang PP, Li YQ, He QM, Yang XJ, Lei Y, Tang LL, Zhou GQ, Mao YP, Wei C, Xiong KX, Zhang HB, Zhu SD, Hou Y, Sun Y, Dean M, Amit I, Wu K*, Kuang DM*, Li GB*, Liu N*, Ma J*., 2020
Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma., Li XF, Chen DP, Ouyang FZ, Chen MM, Wu Y, Kuang DM*, Zheng L*., 2015

Tumor Immunity Metabolism Myeloid Cells Inflammation Tissue Microenvironment Cancer Research

Kun Chen - Tongji University

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