Professor | 陈东萍 | 数字化转型顾问

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Name	陈东萍
Contact Information	chendp23@mail.sysu.edu.cn
Language ability	中文, 英文
Province	广东

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Name

陈东萍

Contact Information

chendp23@mail.sysu.edu.cn

Language ability

中文, 英文

Province

广东

University/Lab Affiliation and Title	中山大学
Faculty	Life Sciences
Academic Background & Achievements	2013/09-2018/07 生物化学与分子生物学博士: 中山大学以肿瘤这一可切除的组织为研究模型，开展了能量代谢决定细胞命运/免疫微环境特征及对疾病进展影响的原创性研究
Work Experience	2023/02-至今 - 中山大学 - 副教授 2021/11-2023/01 - 中山大学 - 副研究员 2018/08-2021/11 - 中山大学 - 博士后

University/Lab Affiliation and Title

中山大学

Faculty

Life Sciences

Academic Background & Achievements

2013/09-2018/07 生物化学与分子生物学博士: 中山大学
以肿瘤这一可切除的组织为研究模型，开展了能量代谢决定细胞命运/免疫微环境特征及对疾病进展影响的原创性研究

Work Experience

2023/02-至今 - 中山大学 - 副教授
2021/11-2023/01 - 中山大学 - 副研究员
2018/08-2021/11 - 中山大学 - 博士后

Areas of Focus	肿瘤免疫与代谢髓系细胞炎性组织微环境
Publications	Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma., Chen DP, Ning WR, Jiang ZZ, Peng ZP, Zhu LY, Zhuang SM, Kuang DM, Zheng L, Wu Y., 2019 Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma., Chen DP, Ning WR, Li XF, Wei Y, Lao XM, Wang JC, Wu Y, Zheng L., 2018 Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., Wu RQ#, Lao XM#, Chen DP#, Qin H, Mu M, Cao WJ, Deng J, Wan CC, Zhan WY, Wang JC, Xu L, Chen MS, Gao Q, Zheng L, Wei Y, Kuang DM., 2023 PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma., Wang JC#, Chen DP#, Lu SX#, Chen JB#, Wei Y#, Liu XC#, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM, Chen MS, Zhou ZG., 2022 B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis., Zeng QH#, Wei Y#, Lao XM#, Chen DP#, Huang CX, Lin QY, He M, Liao Y, Zheng L, Li B, Zhang GB, Chen Y, Kuang DM., 2020 Identification of cross-talk between m6A and 5mC regulators associated with onco-immunogenic features and prognosis across 33 cancer types., Chen YT#, Shen JY#, Chen DP#, Wu CF, Guo R, Zhang PP, Lv JW, Li WF, Wang ZX, Chen YP., 2020 Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma., Chen YP#, Yin JH#, Li WF#, Li HJ#, Chen DP#, Zhang CJ#, Lv JW, Wang YQ, Li XM, Li JY, Zhang PP, Li YQ, He QM, Yang XJ, Lei Y, Tang LL, Zhou GQ, Mao YP, Wei C, Xiong KX, Zhang HB, Zhu SD, Hou Y, Sun Y, Dean M, Amit I, Wu K, Kuang DM, Li GB, Liu N, Ma J., 2020 Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma., Li XF, Chen DP, Ouyang FZ, Chen MM, Wu Y, Kuang DM, Zheng L., 2015

Areas of Focus

肿瘤免疫与代谢
髓系细胞
炎性组织微环境

Publications

Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma., Chen DP, Ning WR, Jiang ZZ, Peng ZP, Zhu LY, Zhuang SM, Kuang DM, Zheng L*, Wu Y*., 2019
Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma., Chen DP, Ning WR, Li XF, Wei Y, Lao XM, Wang JC, Wu Y*, Zheng L*., 2018
Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., Wu RQ#, Lao XM#, Chen DP#, Qin H, Mu M, Cao WJ, Deng J, Wan CC, Zhan WY, Wang JC, Xu L, Chen MS, Gao Q, Zheng L, Wei Y*, Kuang DM*., 2023
PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma., Wang JC#, Chen DP#, Lu SX#, Chen JB#, Wei Y#, Liu XC#, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM*, Chen MS*, Zhou ZG*., 2022
B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis., Zeng QH#, Wei Y#, Lao XM#, Chen DP#, Huang CX, Lin QY, He M, Liao Y, Zheng L, Li B, Zhang GB*, Chen Y*, Kuang DM*., 2020
Identification of cross-talk between m6A and 5mC regulators associated with onco-immunogenic features and prognosis across 33 cancer types., Chen YT#, Shen JY#, Chen DP#, Wu CF, Guo R, Zhang PP, Lv JW, Li WF*, Wang ZX*, Chen YP*., 2020
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma., Chen YP#, Yin JH#, Li WF#, Li HJ#, Chen DP#, Zhang CJ#, Lv JW, Wang YQ, Li XM, Li JY, Zhang PP, Li YQ, He QM, Yang XJ, Lei Y, Tang LL, Zhou GQ, Mao YP, Wei C, Xiong KX, Zhang HB, Zhu SD, Hou Y, Sun Y, Dean M, Amit I, Wu K*, Kuang DM*, Li GB*, Liu N*, Ma J*., 2020
Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma., Li XF, Chen DP, Ouyang FZ, Chen MM, Wu Y, Kuang DM*, Zheng L*., 2015

肿瘤免疫代谢髓系细胞炎症组织微环境癌症研究

陈坤 - 同济大学

林昶东 - 同济大学

Area of Focus
细胞粘附 | 信号传导 | 发展 | 感染 | 免疫 | 癌症 | 衰老 | 分子机制 | 病理生理学 | 治疗干预

汪世龙 - 同济大学

Area of Focus
干细胞 | 纳米材料 | 分化 | 更新 | 药物载体 | 哮喘 | 炎症 | 肿瘤 | 脊髓 | 修复

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