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Yan Huang
huangy336@mail.sysu.edu.cn
Chinese, English
Guangdong
Sun Yat-Sen University
Life Sciences
  • 2006.9-2012.6 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
  • 2002.9-2006.6 Bachelor's: Nanjing University, Department of Biotechnology
  • 2012: Reported new function of transcription mediator complex coupling RNA processing (Mol Cell cover)
  • Received the Excellent Award from the President of the Chinese Academy of Sciences
  • Received the Excellent Doctoral Dissertation Award
  • Received the Johnson Asia Excellent Paper First Prize
  • 2019.1-Present - Sun Yat-sen University - Associate Professor
  • 2012.8-2018.12 - Sun Yat-sen University - Lecturer, 'Hundred Talents Program'
  • 2006.9-2012.6 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - PhD Candidate
  • 2017: Second Prize in National University Biology Microlecture Competition
  • 2018: Second Prize in Guangdong Province Teaching Achievement Award (Participant)
  • Sun Yat-sen University 8th Teaching Achievement Award First Prize (Participant)
  • 2017: Guangzhou Pearl River Science and Technology New Star
Cellular senescence and telomere regulation
Tumor cell aging and intervention
  • ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader, Chuanle Wang, Yan Huang, Yue Yang, Ruofei Li, Yingying Li, Hongxin Qiu, Jiali Wu, Guang Shi, Wenbin Ma, Zhou Songyang, 2023
  • Regulation of telomerase towards tumor therapy, Siyu Yan, Song Lin, Hongxin Qiu, Yan Huang, 2023
  • TIN2 deficiency leads to ALT-associated phenotypes and differentiation defects in embryonic stem cells, Shanshan Yin, Fangyingnan Zhang, Song Lin, Wei Chen, Kai Weng, Dan Liu, Chuanle Wang, Zibin He, Yuxi Chen, Wenbin Ma, Junjiu Huang, Yan Huang, Zhou Songyang, 2022
  • Natural Product Library Screens Identify Sanguinarine Chloride as a Potent Inhibitor of Telomerase Expression and Activity, Siyu Yan, Song Lin, Kexin Chen, Shanshan Yin, Haoyue Peng, Nanshuo Cai, Wenbin Ma, Zhou Songyang, Yan Huang, 2022
  • Induction of Accelerated Aging in a Mouse Model, Nanshuo Cai, Yifan Wu, Yan Huang, 2022
  • TRIM28 inhibits alternative lengthening of telomere phenotypes by protecting SETDB1 from degradation, Chuanle Wang, Zhou Songyang, Yan Huang, 2021
  • MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence, Tingting Li, Zhenhua Luo, Song Lin, Chujun Li, Shenkun Dai, Haoli Wang, Junjiu Huang, Wenbin Ma, Zhou Songyang, Yan Huang, 2020
  • TOE1 Acts as a 3’ Exonuclease For Telomerase RNA and Regulates Telomere Maintenance, Tingting Deng, Yan Huang, Kai Weng, Song Lin, Yujing Li, Guang Shi, Yali Chen, Junjiu Huang, Dan Liu, Wenbin Ma, Zhou Songyang, 2019
  • Analysis of hpf1 expression and function in early embryonic development of zebrafish, Zhen Zhang, Hongwei Sun, Yu Chen, Tianqi Cao, Zhou Songyang, Junjiu Huang, Yan Huang, 2018
  • Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility, Yuxi Chen, Puping Liang, Yan Huang, Minyan Li, Xiya Zhang, Chenhui Ding, Junyan Feng, Zhen Zhang, Xueqing Zhang, Yuanzhu Gao, Qinfeng Zhang, Shanbo Cao, Haiyan Zheng, Dan Liu, Zhou Songyang, Junjiu Huang, 2017
  • SmedOB1 is Required for Planarian Homeostasis and Regeneration, Shanshan Yin, Yan Huang, Yingnan Zhangfang, Qiaoqin Zhong, Pengqing Li, Junjiu Huang, Dan Liu, Zhou Songyang, 2016
  • Ccndbp1 is a new positive regulator of skeletal myogenesis, Yan Huang, Bohong Chen, Miaoman Ye, Puping Liang, Yingnan Zhangfang, Junjiu Huang, Mingyao Liu, Zhou Songyang, Wenbin Ma, 2016
  • Specific Tandem 3'UTR Patterns and Gene Expression Profiles in Mouse Thy1+ Germline Stem Cells, Yan Huang, Yuanyan Xiong, Zhuoheng Lin, Xuyang Feng, Xue Jiang, Zhou Songyang, Junjiu Huang, 2015
  • 'Mediator-ing' messenger RNA processing, Yan Huang, Xiao Yao, Gang Wang, 2015
  • Telomere regulation in pluripotent stem cells, Yan Huang, Puping Liang, Dan Liu, Junjiu Huang, Zhou Songyang, 2014
  • Mediator Complex Regulates Alternative mRNA Processing via the MED23 Subunit, Yan Huang, Wencheng Li, Xiao Yao, Qi-jiang Lin, Jing-wen Yin, Yan Liang, Monika Heiner, Bin Tian, Jingyi Hui, Gang Wang, 2012
  • Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb, Wei Wang, Xiao Yao, Yan Huang, Xiangming Hu, Runzhong Liu, Dongming Hou, Ruichuan Chen, Gang Wang, 2013
  • MicroRNA-509-3p increases the sensitivity of epithelial ovarian cancer cells to cisplatin-induced apoptosis, Wei Chen, Wenshu Zeng, Xiaodi Li, Weiliang Xiong, Mengdie Zhang, Yan Huang, Longshu Zhou, Songshan Jiang, 2016
  • Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation, Jing-wen Yin, Yan Liang, Ji Yeon Park, Dongrui Chen, Xiao Yao, Qi Xiao, Zhen Liu, Bo Jiang, Yu Fu, Menghan Bao, Yan Huang, Yuting Liu, Jun Yan, Min-sheng Zhu, Zhongzhou Yang, Pingjin Gao, Bin Tian, Dangsheng Li, Gang Wang, 2012
  • Mediator MED23 links insulin signaling to the adipogenesis transcription cascade, Wei Wang, Lu Huang, Yan Huang, Jing-wen Yin, Arnold J. Berk, Jeffrey M. Friedman, Gang Wang, 2009
  • Oral delivery of tumor-targeting Salmonella exhibits promising therapeutic efficacy and low toxicity, Guo Chen, Dong-Ping Wei, Li-Jun Jia, Bo Tang, Luan Shu, Kui Zhang, Yun Xu, Jing Gao, Xiao-Feng Huang, Wen-Hui Jiang, Qin-Gang Hu, Yan Huang, Qiang Wu, Zhi-Hua Sun, Jian-Fa Zhang, Zi-Chun Hua, 2009
  • Oral delivery of tumor-targeting Salmonella for cancer therapy in murine tumor models, Li-Jun Jia, Dong-Ping Wei, Qi-Ming Sun, Yan Huang, Qiang Wu, Zi-Chun Hua, 2007
  • Tumor-targeting Salmonella typhimurium improves cyclophosphamide chemotherapy at maximum tolerated dose and low-dose metronomic regimens in a murine melanoma model, Li-Jun Jia, Dong-Ping Wei, Qi-Ming Sun, Guang-Hui Jin, Shu-Feng Li, Yan Huang, Zi-Chun Hua, 2007
  • Research progress on telomere dysfunction syndrome, Wang Chuanle, Yan Huang, Songyang Zhou, 2021
  • Preliminary exploration of the reform of life science undergraduate training by integrating graduation design with summer term experimental skills courses, Yan Huang, Junjiu Huang, 2017
  • Discussion on cell therapy from the perspective of management, Qian Cheng, Yan Huang, 2016
  • Induction of pluripotent stem cells by specific factors, Shan Zhongshen, Yan Huang, 2010
Cellular Senescence Telomere Regulation Tumor Cells Intervention Stem Cells Immune Cells Mouse Model Pathways Interaction

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