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Shouheng Jin
Life Science
Sun Yat-Sen University
Guangdong
Language: Chinese, English
Immunometabolism
Molecular Mechanisms
Autophagy
Non-Canonical
Antiviral
Signaling Pathways
Intervention
Immune Response
Protein Factors
Cellular Pathways
Areas of Focus
- Molecular mechanisms of immunometabolism
- Mechanisms of non-canonical autophagy
- Antiviral signaling pathways and intervention mechanisms
Work Experience
- 2019/05-present - Sun Yat-sen University, School of Life Sciences - Associate Professor
- 2016/07-2019/04 - Sun Yat-sen University, School of Life Sciences - Specially Appointed Associate Researcher
Academic Background & Achievements
- 2013/09-2016/06 - PhD in Science: Sun Yat-sen University
- Achievement: Published 9 SCI research papers as first or corresponding author, focusing on innate immune regulatory networks.
Publications
- ATG4B antagonizes antiviral immunity by GABARAP-directed autophagic degradation of TBK1, Weihong Xie, Chenqiu Zhang, Zheyu Wang, Hui Chen, Tonghui Gu, Tao Zhou, Yaoxing Wu, Fan Xia, Min Li, Jun Wang, Renjie Jiao, Jun Cui, Shouheng Jin, 2023
- Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy, Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui, 2022
- Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation, Lingli Zhou, Xing He, Liqiu Wang, Ping Wei, Zhe Cai, Song Zhang, Shouheng Jin, Huasong Zeng, Jun Cui, 2022
- Igniting autophagy through the regulation of phase separation, Shouheng Jin, Jun Cui, 2020
- High-throughput screening of functional deubiquitinating enzymes in autophagy, Shuo Tian, Shouheng Jin, Yaoxing Wu, Tao Liu, Man Luo, Jiayu Ou, Weihong Xie, Jun Cui, 2020
- The NEDD4-USP13 axis facilitates autophagy via deubiquitinating PIK3C3, Weihong Xie, Shouheng Jin, Jun Cui, 2020
- Auto-ubiquitination of NEDD4-1 recruits USP13 to facilitate autophagy through deubiquitinating VPS34, Weihong Xie, Shouheng Jin, Yaoxing Wu, Huifang Xian, Shuo Tian, Di-Ao Liu, Zhiyong Guo, Jun Cui, 2020
- LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I, Huifang Xian, Shuai Yang, Shouheng Jin, Yuxia Zhang, Jun Cui, 2020
- The cross-regulation between autophagy and type I interferon signaling in host defense, Shouheng Jin, 2019
- m6A RNA modification controls autophagy through upregulating ULK1 protein abundance, Shouheng Jin, Xiya Zhang, Yanyan Miao, Puping Liang, Kaiyu Zhu, Yuanchu She, Yaoxing Wu, Di-Ao Liu, Junjiu Huang, Jian Ren, Jun Cui, 2018
- BST2 inhibits type I IFN (interferon) signaling by accelerating MAVS degradation through CALCOCO2-directed autophagy, Shouheng Jin, Jun Cui, 2018
- Tetherin suppresses type I interferon signaling by targeting MAVS for NDP52-mediated selective autophagic degradation in human cells, Shouheng Jin, Shuo Tian, Man Luo, Weihong Xie, Tao Liu, Tianhao Duan, Yaoxing Wu, Jun Cui, 2017
- USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin-1, Shouheng Jin, Shuo Tian, Yamei Chen, Chuanxia Zhang, Weihong Xie, Xiaojun Xia, Jun Cui, Rong-Fu Wang, 2016
- The BECN1-USP19 axis plays a role in the crosstalk between autophagy and antiviral immune responses, Jun Cui, Shouheng Jin, Rong-Fu Wang, 2016
