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Nengming Xiao
Life Science
Xiamen University
Fujian
Language: English, Chinese
T Cells
Activation
Differentiation
Molecular Mechanisms
Follicular Helper T Cells
Cytotoxic T Cells
Regulatory T Cells
Antiviral
Antitumor
Autoimmune Diseases
Areas of Focus
- Molecular mechanisms of T cell activation and differentiation
Work Experience
- 2006-2009 - The Scripps Research Institute - Postdoctoral Fellow
- 2009-2010 - Cleveland Clinic - Postdoctoral Fellow
- 2010-2014 - La Jolla Institute for Allergy and Immunology - Postdoctoral Fellow
- 2014-Present - Xiamen University, School of Life Sciences - Professor
Academic Background & Achievements
- 2000 - Bachelor's Degree in Biochemistry: Beijing Normal University
- 2006 - Ph.D. in Biochemistry and Molecular Biology: Peking University
Publications
- Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling., Chen Q, Zhuang S, Hong Y, Yang L, Guo P, Mo P, Peng K, Li W, Xiao N, Yu C., 2022
- Mitochondrial C1qbp promotes differentiation of effector CD8(+) T cells via metabolic-epigenetic reprogramming., Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, Zhou S, Wang X, Niu Y, Hong Y, Lin SH, Liu WH, Xiao C, Li Q, Xiao N., 2021
- Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death., Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N., 2021
- The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells., Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC., 2014
- iRhom2 is required for the secretion of mouse TNFalpha., Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B., 2012
- Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria., Xu L, Xiao N, Liu F, Ren H, Gu J., 2009
- The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease., Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B., 2009
