Professor | Nengming Xiao | Asia Growth Partners

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Name	Nengming Xiao
Contact Information	nengming@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Nengming Xiao

Contact Information

nengming@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2000 - Bachelor's Degree in Biochemistry: Beijing Normal University 2006 - Ph.D. in Biochemistry and Molecular Biology: Peking University
Work Experience	2006-2009 - The Scripps Research Institute - Postdoctoral Fellow 2009-2010 - Cleveland Clinic - Postdoctoral Fellow 2010-2014 - La Jolla Institute for Allergy and Immunology - Postdoctoral Fellow 2014-Present - Xiamen University, School of Life Sciences - Professor

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2000 - Bachelor's Degree in Biochemistry: Beijing Normal University
2006 - Ph.D. in Biochemistry and Molecular Biology: Peking University

Work Experience

2006-2009 - The Scripps Research Institute - Postdoctoral Fellow
2009-2010 - Cleveland Clinic - Postdoctoral Fellow
2010-2014 - La Jolla Institute for Allergy and Immunology - Postdoctoral Fellow
2014-Present - Xiamen University, School of Life Sciences - Professor

Areas of Focus	Molecular mechanisms of T cell activation and differentiation
Publications	Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling., Chen Q, Zhuang S, Hong Y, Yang L, Guo P, Mo P, Peng K, Li W, Xiao N, Yu C., 2022 Mitochondrial C1qbp promotes differentiation of effector CD8(+) T cells via metabolic-epigenetic reprogramming., Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, Zhou S, Wang X, Niu Y, Hong Y, Lin SH, Liu WH, Xiao C, Li Q, Xiao N., 2021 Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death., Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N., 2021 The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells., Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC., 2014 iRhom2 is required for the secretion of mouse TNFalpha., Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B., 2012 Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria., Xu L, Xiao N, Liu F, Ren H, Gu J., 2009 The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease., Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B., 2009

Areas of Focus

Molecular mechanisms of T cell activation and differentiation

Publications

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling., Chen Q, Zhuang S, Hong Y, Yang L, Guo P, Mo P, Peng K, Li W, Xiao N, Yu C., 2022
Mitochondrial C1qbp promotes differentiation of effector CD8(+) T cells via metabolic-epigenetic reprogramming., Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, Zhou S, Wang X, Niu Y, Hong Y, Lin SH, Liu WH, Xiao C, Li Q, Xiao N., 2021
Ddb1 Is Essential for the Expansion of CD4(+) Helper T Cells by Regulating Cell Cycle Progression and Cell Death., Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N., 2021
The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells., Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC., 2014
iRhom2 is required for the secretion of mouse TNFalpha., Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B., 2012
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria., Xu L, Xiao N, Liu F, Ren H, Gu J., 2009
The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease., Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B., 2009

T Cells Activation Differentiation Molecular Mechanisms Follicular Helper T Cells Cytotoxic T Cells Regulatory T Cells Antiviral Antitumor Autoimmune Diseases

Shengdian Wang - University of Chinese Academy of Sciences

Hua Gu - Tongji University

Hua Gu - Tongji University

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