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Ling-Ling Zheng
zhengll33@mail.sysu.edu.cn
Chinese, English
Guangdong
Sun Yat-Sen University
Life Sciences
  • 2009.09-2012.06 Doctorate: Sun Yat-sen University, Biochemistry and Molecular Biology
  • 2006.09-2009.06 Master's: Sun Yat-sen University, Information Biology
  • 2002.09-2006.06 Bachelor's: Northeast Forestry University, Computer Science
  • Published 23 papers in international journals
  • Developed comprehensive non-coding RNA databases
  • 2021.11-present - Sun Yat-sen University, Deputy Director of Bioengineering Research Center
  • 2021.10-present - Sun Yat-sen University, Director of Innovation Center for Life Sciences
  • 2019.10-present - Sun Yat-sen University, Full-time Counselor for Young Teachers
  • 2017.01-2020.10 - Sun Yat-sen University, Party Branch Secretary of Bioengineering Center
  • 2017.01-present - Sun Yat-sen University, Associate Professor
  • 2012.07-2016.12 - Sun Yat-sen University, Lecturer
  • 2018: First Prize in National University Microlecture Teaching Competition (Life Sciences)
  • 2018: Second Prize in Guangdong Province Young Teachers Teaching Competition (Science and Engineering)
  • 2017: Second Prize in Sun Yat-sen University Young Teachers Teaching Competition (Science and Engineering)
  • 2014: Wens Outstanding Young Teacher Award at Sun Yat-sen University
  • 2013-2015: Best Software Project and Gold Award at IGEM
Functional Genomics and Bioinformatics
Non-coding RNA Regulatory Networks and Major Diseases
High-throughput Sequencing Data Analysis and Application
Pathogen-host Interaction Networks
Synthetic Biology (Nucleic Acid Therapy)
Machine Learning/Deep Learning Algorithm Development
  • GateView: A Multi-Omics Platform for Gene Feature Analysis of Virus Receptors within Human Normal Tissues and Tumors., Sun Y, Huang ZL, Chen WX, Zhang YF, Lei HT, Huang QJ, Lun ZR, Qu LH, Zheng LL, 2024
  • Integrative profiling of extrachromosomal circular DNA in placenta and maternal plasma provides insights into the biology of fetal growth restriction and reveals potential biomarkers., Lin M, Chen Y, Xia S, He Z, Yu X, Huang L, Lin S, Liang B, Huang Z, Mei S, Liu D, Zheng L, Luo Y, 2023
  • tModBase: deciphering the landscape of tRNA modifications and their dynamic changes from epitranscriptome data., Hao-Tian Lei, Zhang-Hao Wang, Bin Li, Yang Sun, Shi-Qiang Mei, Jian-Hua Yang, Liang-Hu Qu, Ling-Ling Zheng, 2023
  • SARS-CoV-2 causes a significant stress response mediated by small RNAs in the blood of COVID-19 patients., Liu X, Wen YZ, Huang ZL, Shen X, Wang JH, Luo YH, Chen WX, Lun ZR, Li HB, Qu LH, Shan H, Zheng LL, 2022
  • Integrated Analysis Reveals the Characteristics and Effects of SARS-CoV-2Maternal-Fetal Transmission., Huang Z, Xia S, Mei S, Wen Y, Liu J, Dong C, Chen W, Yu P, Qu L, Luo Y, Zheng L, 2022
  • tsRFun: a comprehensive platform for decoding human tsRNA expression, functions and prognostic value by high-throughput small RNA-Seq and CLIP-Seq data., Jun-Hao Wang, Wen-Xin Chen, Shi-Qiang Mei, Yue-Dong Yang, Jian-Hua Yang, Liang-Hu Qu, Ling-Ling Zheng, 2021
  • Pol3Base: a resource for decoding the interactome, expression, evolution, epitranscriptome and disease variations of Pol III-transcribed ncRNAs., Li Cai, Jia-jia Xuan, Qiao Lin, Jun-Hao Wang, Shun Liu, Fang-Zhou Xie, Ling-Ling Zheng, Bin Li, Liang-hu Qu, Jian-Hua Yang, 2021
  • N6-methyladenine demethylase ALKBH1 inhibits the differentiation of skeletal muscle., Li-Ting Diao, Shu-Juan Xie, Pei-Jie Yu, Yu-Jia Sun, Fan Yang, Ye-Ya Tan, Shuang Tao, Ya-Rui Hou, Ling-Ling Zheng, Zhen-Dong Xiao, Qi Zhang, 2021
  • PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks., Ye-Ya Tan, Yin Zhang, Bin Li, Yang-Wen Ou, Shu-Juan Xie, Pei-Pei Chen, Shi-Qiang Mei, Qiao-Juan Huang, Ling-Ling Zheng, Liang-Hu Qu, 2021
  • ColorCells: A database of expression, classification and functions of lncRNAs in single cells., Ling-Ling Zheng, Jing-Hua Xiong, Wu-Jian Zheng, Jun-Hao Wang, Zi-Liang Huang, Zhi-Rong Chen, Xin-Yao Sun, Yi-Min Zheng, Ke-Ren Zhou, Bin Li, Shun Liu, Liang-Hu Qu, Jian-Hua Yang, 2020
  • deepBase v3.0: expression atlas and interactive analysis of ncRNAs from thousands of deep-sequencing data., Fangzhou Xie, Shurong Liu, Junhao Wang, Jiajia Xuan, Xiaoqin Zhang, Lianghu Qu, Lingling Zheng, Jianhua Yang, 2020
  • 走向国际前沿的中国RNA研究., 郑凌伶,戚益军,屈良鹄, 2019
  • “真凶密码—DNA指纹图谱制作思路”微课教案., 郑凌伶, 2019
  • Chinese RNA research leading to the international science and technology frontier., Ling-Ling Zheng, Yi-Jun Qi, Liang-Hu Qu, 2019
  • dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease., Ling-Ling Zheng, Ke-Ren Zhou, Shun Liu, Ding-Yao Zhang, Ze-Lin Wang, Zhi-Rong Chen, Jian-Hua Yang, Liang-Hu Qu, 2018
  • Exo-miRExplorer: A Comprehensive Resource for Exploring and Comparatively Analyzing Exogenous MicroRNAs., Ling-Ling Zheng, Kai-Wen Deng, An-Cheng Deng, Jie Wu, Jian-Hua Yang, Zhao-Rong Lun, Liang-Hu Qu, 2017
  • tRF2Cancer: A web server to detect tRNA-derived small RNA fragments (tRFs) and their expression in multiple cancers., Ling-Ling Zheng, Wei-Lin Xu, Shun Liu, Wen-Ju Sun, Jun-Hao Li, Jie Wu, Jian-Hua Yang, Liang-Hu Qu, 2016
  • deepBase v2.0: Identification, Expression, Evolution and Function of Small RNAs, LncRNAs and Circular RNAs from Deep-sequencing Data., Ling-Ling Zheng, Jun-Hao Li, Jie Wu, Wen-Ju Sun, Shun Liu, Ze-lin Wang, Hui Zhou, Jian-Hua Yang, Liang-Hu Qu, 2015
  • Application of microRNA gene resources in the improvement of agronomic traits in rice., Ling-Ling Zheng and Liang-Hu Qu, 2015
  • Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei., Ling-Ling Zheng, Yan-Zi Wen, Jian-Hua Yang, Jian-You Liao, Peng Shao, Hui Xu, Hui Zhou, Jun-Zhi Wen, Zhao-Rong Lun, Francisco J Ayala, Liang-Hu Qu, 2013
  • Pseudogene-derived small interference RNAs regulate gene expression in African Trypanosoma brucei., Yan-Zi Wen, Ling-Ling Zheng, Jian-You Liao, Ming-Hui Wang, Yin Wei, Xue-Min Guo, Liang-Hu Qu, Francisco J. Ayala, Zhao-Rong Lun, 2011
  • Computational RNomics: structure identification and functional prediction of non-coding RNAs in silico., Ling-Ling Zheng and Liang-Hu Qu, 2010
  • Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Jun-Hao Li, Sun Liu, Ling-Ling Zheng, Jie Wu, Wen-Ju Sun, Ze-Lin Wang, Hui Zhou, Liang-Hu Qu, Jian-Hua Yang, 2015
  • Computational Approaches to tRNA-Derived Small RNAs., Wei-Lin Xu, Ye Yang, Yi-Dan Wang, Liang-Hu Qu, Ling-Ling Zheng, 2017
  • Pseudogenes are not pseudo any more., Yan-Zi Wen, Ling-Ling Zheng, Liang-Hu Qu, Francisco J Ayala, Zhao-Rong Lun, 2012
  • Both endo-siRNAs and tRNA-derived small RNAs are involved in the differentiation of primitive eukaryote Giardia lamblia., Jian-You Liao, Yan-Hua Guo, Ling-Ling Zheng, Yan Li, Wen-Li Xu, Yu-Chan Zhang, Hui Zhou, Zhao-Rong Lun, Francisco Ayala, Liang-Hu Qu, 2014
  • Cancer in the parasitic protozoans Trypanosoma brucei and Toxoplasma gondii., Zhao-Rong Lun, De-Hua Lai, Yan-Zi Wen, Ling-Ling Zheng, Ji-Long Shen, Ting-Bo Yang, Wen-Liang Zhou, Liang-Hu Qu, Geoff Hide, Francisco J. Ayala, 2015
  • Analysis of the mitochondrial maxicircle of Trypanosoma lewisi, a neglected human pathogen., Ruo-Hong Lin, De-Hua Lai, Ling-Ling Zheng, Jie Wu, Julius Lukeš, Geoff Hide, Zao-Rong Lun, 2015
  • Rapid Birth-and-Death Evolution of Imprinted snoRNAs in the Prader-Willi Syndrome Locus: Implications for Neural Development in Euarchontoglires., Yi-Jun Zhang, Jian-Hua Yang, Qiao-Su Shi, Ling-Ling Zheng, Jun Liu, Hui Zhou, Hui Zhang, Liang-Hu Qu, 2014
  • ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data., Ke-Ren Zhou, Shun Liu, Wen-Ju Sun, Ling-Ling Zheng, Hui Zhou, Jian-Hua Yang, Liang-Hu Qu, 2016
  • A Contig-Based Strategy for the Genome-Wide Discovery of MicroRNAs without Complete Genome Resources., Jun-Zhi Wen, Jian-You Liao, Ling-Ling Zheng, Hui Xu, Jian-Hua Yang, Dao-Gang Guan, Si-Min Zhang, Hui Zhou, Liang-Hu Qu, 2014
  • RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data., Jia-Jia Xuan, Wen-Ju Sun, Peng-Hui Lin, Ke-Ren Zhou, Shun Liu, Ling-Ling Zheng, Liang-Hu Qu, Jian-Hua Yang, 2017
  • Drastic expression change of transposon-derived piRNA-like RNAs and microRNAs in early stages of chicken embryos implies a role in gastrulation., Peng Shao, Jian-You Liao, Dao-Gang Guan, Jian-Hua Yang, Ling-Ling Zheng, Qing Jing, Hui Zhou, Liang-Hu Qu, 2012
  • A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL., Bo-Wei Han, Dan-Dan Feng, Zhi-Gang Li, Xue-Qun Luo, Hua Zhang, Xiao-Juan Li, Xing-Ju Zhang, Ling-Ling Zheng, Cheng-Wu Zeng, Kang-Yu Lin, Peng Zhang, Ling Xu, Yue-Qin Chen, 2011
Genomics Bioinformatics Rna Regulatory Networks Diseases Sequencing Pathogen Host Synthetic Biology Machine Learning

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