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Zhiyong Liu
Neuroscience Chinese academy of sciences
Chinese Academy of Sciences
Shanghai
Language: English, Chinese
Auditory System
Cell Subtype
Rna-Seq
Gene Expression
Signal Networks
Mouse Models
Hearing Loss
Regeneration
Neuroscience
Stem Cells
Areas of Focus
- Auditory System Cell Subtype Identification
- Core Regulatory Genes and Signal Networks in Cell Development
- Mouse Models for Human Hearing Loss and Regeneration
Work Experience
- 2011-2012 - St. Jude Children's Research Hospital - Research Assistant
- 2012-2016 - Howard Hughes Medical Institute - Postdoctoral Researcher
- 2016-present - Chinese Academy of Sciences, Institute of Neuroscience - Research Group Leader
Academic Background & Achievements
- 1998-2003 Bachelor: Sichuan University, West China School of Basic Medical Sciences & Forensic Medicine
- 2003-2006 Master: Sichuan University, West China School of Basic Medical Sciences & Forensic Medicine
- 2006-2011 PhD: University of Tennessee Health Science Center/St. Jude Children's Research Hospital
Publications
- Revisiting the Potency of Tbx2 Expression in Transforming Outer Hair Cells into Inner Hair Cells at Multiple Ages In Vivo., Bi, Z., Ren, M., Zhang, Y., He, S., Song, L., Li, X.*, Liu, Z.*, 2024
- Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival., WANG, G., Gu, Y., Liu, Z.*, 2024
- Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex., Chen, A., Sun, Y., Lei, Y., Li, C., Liao, S., Meng, J., Bai, Y., Liu, Z., Liang, Z., Zhu, Z., Yuan, N., Yang, H., Wu, Z., Lin, F., Wang, K., Li, M., Zhang, S., Xiang, B., Li, S., Li, H., Chen, M., Wang, S., Li, M., Liu, W., Liu, X., Zhao, Q., Lisby, M., Wang, J., Fang, J., Lin, Y., Xie, Q., Liu, Z., He, J., Xu, H., Huang, W., Mulder, J., Yang, H., Sun, Y., Uhlen, M., Poo, M., Wang, J., Yao, J*., Wei, W.*, Li, Y.*, Shen, Z.*, Liu, L.*, Liu, Z.*, Xu, X.*, Li, C.*, 2023
- In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2., Li, X., Ren, Y., Gu, Y., Zhu, T., Zhang, Y., Li, J., Li, C., Wang, G., Song, L., Bi, Z.*, Liu, Z.*, 2023
- Recent advances in molecular studies on cochlear development and regeneration., Sun, Y. Liu, Z.*, 2023
- Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development., Li, S., He, S., Lu, Y., Jia, S., Liu, Z.*, 2023
- Development and transdifferentiation into inner hair cells require Tbx2., Bi, Z., Li, X., Ren, M., Gu, Y., Zhu, T., Li, S., Wang, G., Sun, S., Sun, Y., Liu, Z.*, 2022
- Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development., Luo, Z., Du, Y., Li, S., Zhang, H., Shu, M., Zhang, D., He, S., Wang, G., Lu, F*., Liu, Z.*, 2022
- Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages., Sun, Y., Wang, L., Zhu, T., Wu, B., Wang, G., Luo, Z., Li, C*., Wei, W*., Liu, Z.*, 2022
- Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells., Sun, S.#, Li S.#, Luo, Z.#, Ren, M., He, S., Wang, G., Liu, Z.*, 2021
- Mosaic CRISPR-stop enables rapid phenotyping of nonsense mutations in essential genes., Wang, G.#, Li, C.#, He, S., Liu, Z.*, 2021
- Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages., Li, C., Li X., Bi Z., Sugino K., Wang G., Zhu T., Liu, Z.,*, 2020
- Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing., Zhang, H, Pan, H, Zhou, C., Wei, Y, Ying, W., Li, S., Wang, G., Li, C, Ren, Y., Li, G, Ding, X, Sun, Y., Li, GL, Song, L, Li, Y., Yang, H*, Liu, Z.*, 2018
