Professor | 刘志勇 | 数字化转型顾问

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Name	刘志勇
Contact Information	zhiyongliu@@ion.ac.cn
Language ability	英语, 中文
Province	上海

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Name

刘志勇

Contact Information

zhiyongliu@@ion.ac.cn

Language ability

英语, 中文

Province

上海

University/Lab Affiliation and Title	中国科学院
Faculty	institute of neuroscience Chinese academy of sciences
Academic Background & Achievements	1998-2003 学士学位: 四川大学华西基础医学与法医学院 2003-2006 硕士学位: 四川大学华西基础医学与法医学院 2006-2011 博士学位: 美国田纳西大学健康科学中心/St.Jude儿童研究医院
Work Experience	2011-2012 - 美国St.Jude儿童研究医院 - 研究助理 2012-2016 - 霍华德.休斯医学研究所 - 博士后研究员 2016至今 - 中国科学院脑科学与智能技术卓越创新中心 - 听觉系统发育再生研究组组长

University/Lab Affiliation and Title

中国科学院

Faculty

institute of neuroscience Chinese academy of sciences

Academic Background & Achievements

1998-2003 学士学位: 四川大学华西基础医学与法医学院
2003-2006 硕士学位: 四川大学华西基础医学与法医学院
2006-2011 博士学位: 美国田纳西大学健康科学中心/St.Jude儿童研究医院

Work Experience

2011-2012 - 美国St.Jude儿童研究医院 - 研究助理
2012-2016 - 霍华德.休斯医学研究所 - 博士后研究员
2016至今 - 中国科学院脑科学与智能技术卓越创新中心 - 听觉系统发育再生研究组组长

Areas of Focus	听觉系统细胞亚型鉴定细胞发育成熟过程中的核心调控基因和信号网络人类听力损伤和再生的小鼠疾病模型
Publications	Revisiting the Potency of Tbx2 Expression in Transforming Outer Hair Cells into Inner Hair Cells at Multiple Ages In Vivo., Bi, Z., Ren, M., Zhang, Y., He, S., Song, L., Li, X., Liu, Z., 2024 Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival., WANG, G., Gu, Y., Liu, Z., 2024 Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex., Chen, A., Sun, Y., Lei, Y., Li, C., Liao, S., Meng, J., Bai, Y., Liu, Z., Liang, Z., Zhu, Z., Yuan, N., Yang, H., Wu, Z., Lin, F., Wang, K., Li, M., Zhang, S., Xiang, B., Li, S., Li, H., Chen, M., Wang, S., Li, M., Liu, W., Liu, X., Zhao, Q., Lisby, M., Wang, J., Fang, J., Lin, Y., Xie, Q., Liu, Z., He, J., Xu, H., Huang, W., Mulder, J., Yang, H., Sun, Y., Uhlen, M., Poo, M., Wang, J., Yao, J., Wei, W., Li, Y., Shen, Z., Liu, L., Liu, Z., Xu, X., Li, C., 2023 In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2., Li, X., Ren, Y., Gu, Y., Zhu, T., Zhang, Y., Li, J., Li, C., Wang, G., Song, L., Bi, Z., Liu, Z., 2023 Recent advances in molecular studies on cochlear development and regeneration., Sun, Y. Liu, Z., 2023 Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development., Li, S., He, S., Lu, Y., Jia, S., Liu, Z., 2023 Development and transdifferentiation into inner hair cells require Tbx2., Bi, Z., Li, X., Ren, M., Gu, Y., Zhu, T., Li, S., Wang, G., Sun, S., Sun, Y., Liu, Z., 2022 Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development., Luo, Z., Du, Y., Li, S., Zhang, H., Shu, M., Zhang, D., He, S., Wang, G., Lu, F., Liu, Z., 2022 Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages., Sun, Y., Wang, L., Zhu, T., Wu, B., Wang, G., Luo, Z., Li, C., Wei, W., Liu, Z., 2022 Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells., Sun, S.#, Li S.#, Luo, Z.#, Ren, M., He, S., Wang, G., Liu, Z., 2021 Mosaic CRISPR-stop enables rapid phenotyping of nonsense mutations in essential genes., Wang, G.#, Li, C.#, He, S., Liu, Z., 2021 Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages., Li, C., Li X., Bi Z., Sugino K., Wang G., Zhu T., Liu, Z.,, 2020 Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing., Zhang, H, Pan, H, Zhou, C., Wei, Y, Ying, W., Li, S., Wang, G., Li, C, Ren, Y., Li, G, Ding, X, Sun, Y., Li, GL, Song, L, Li, Y., Yang, H, Liu, Z., 2018

Areas of Focus

听觉系统细胞亚型鉴定
细胞发育成熟过程中的核心调控基因和信号网络
人类听力损伤和再生的小鼠疾病模型

Publications

Revisiting the Potency of Tbx2 Expression in Transforming Outer Hair Cells into Inner Hair Cells at Multiple Ages In Vivo., Bi, Z., Ren, M., Zhang, Y., He, S., Song, L., Li, X.*, Liu, Z.*, 2024
Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival., WANG, G., Gu, Y., Liu, Z.*, 2024
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex., Chen, A., Sun, Y., Lei, Y., Li, C., Liao, S., Meng, J., Bai, Y., Liu, Z., Liang, Z., Zhu, Z., Yuan, N., Yang, H., Wu, Z., Lin, F., Wang, K., Li, M., Zhang, S., Xiang, B., Li, S., Li, H., Chen, M., Wang, S., Li, M., Liu, W., Liu, X., Zhao, Q., Lisby, M., Wang, J., Fang, J., Lin, Y., Xie, Q., Liu, Z., He, J., Xu, H., Huang, W., Mulder, J., Yang, H., Sun, Y., Uhlen, M., Poo, M., Wang, J., Yao, J*., Wei, W.*, Li, Y.*, Shen, Z.*, Liu, L.*, Liu, Z.*, Xu, X.*, Li, C.*, 2023
In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2., Li, X., Ren, Y., Gu, Y., Zhu, T., Zhang, Y., Li, J., Li, C., Wang, G., Song, L., Bi, Z.*, Liu, Z.*, 2023
Recent advances in molecular studies on cochlear development and regeneration., Sun, Y. Liu, Z.*, 2023
Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development., Li, S., He, S., Lu, Y., Jia, S., Liu, Z.*, 2023
Development and transdifferentiation into inner hair cells require Tbx2., Bi, Z., Li, X., Ren, M., Gu, Y., Zhu, T., Li, S., Wang, G., Sun, S., Sun, Y., Liu, Z.*, 2022
Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development., Luo, Z., Du, Y., Li, S., Zhang, H., Shu, M., Zhang, D., He, S., Wang, G., Lu, F*., Liu, Z.*, 2022
Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages., Sun, Y., Wang, L., Zhu, T., Wu, B., Wang, G., Luo, Z., Li, C*., Wei, W*., Liu, Z.*, 2022
Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells., Sun, S.#, Li S.#, Luo, Z.#, Ren, M., He, S., Wang, G., Liu, Z.*, 2021
Mosaic CRISPR-stop enables rapid phenotyping of nonsense mutations in essential genes., Wang, G.#, Li, C.#, He, S., Liu, Z.*, 2021
Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages., Li, C., Li X., Bi Z., Sugino K., Wang G., Zhu T., Liu, Z.,*, 2020
Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing., Zhang, H, Pan, H, Zhou, C., Wei, Y, Ying, W., Li, S., Wang, G., Li, C, Ren, Y., Li, G, Ding, X, Sun, Y., Li, GL, Song, L, Li, Y., Yang, H*, Liu, Z.*, 2018

听觉系统细胞亚型 Rna-Seq 基因表达信号网络小鼠模型听力损伤再生神经科学干细胞

何杰 - 中国科学院

刘真 - 中国科学院

Area of Focus
灵长类 | 胚胎 | 发育 | 生殖 | 干细胞 | 遗传工具 | 大脑 | 认知 | 神经科学 | 研究

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