Professor | Cha-Xiang Guan | Asia Growth Partners

Name	Cha-Xiang Guan
Contact Information	gcxdzd91@163.com
Language ability	Chinese, English
Province	Hunan

Name

Cha-Xiang Guan

Contact Information

gcxdzd91@163.com

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Medicine
Academic Background & Achievements	2001-2006 PhD in Basic Medical Science from Central South University 1987-1990 Master's in Basic Medical Science from Hunan Medical University 1980-1985 Bachelor's in Clinical Medicine from Hunan Medical University Visiting Scholar at University of Southern California
Work Experience	2019.2-present Vice Dean of the Basic Medical College at Central South University 2010.10-2019.1 Vice Dean of the Continuing Education College at Central South University 2005.12-2010.9 Deputy Director of the Graduate School at Central South University 2004.6-present Professor in the Department of Physiology at the Basic Medical College, Central South University 1999.5-2000.11 Visiting Scholar at the University of Southern California
Awards	2019-12-30: Lu Hui-Lin Outstanding Teacher Award

University/Lab Affiliation and Title

Central South University

Faculty

Medicine

Academic Background & Achievements

2001-2006 PhD in Basic Medical Science from Central South University
1987-1990 Master's in Basic Medical Science from Hunan Medical University
1980-1985 Bachelor's in Clinical Medicine from Hunan Medical University
Visiting Scholar at University of Southern California

Work Experience

2019.2-present Vice Dean of the Basic Medical College at Central South University
2010.10-2019.1 Vice Dean of the Continuing Education College at Central South University
2005.12-2010.9 Deputy Director of the Graduate School at Central South University
2004.6-present Professor in the Department of Physiology at the Basic Medical College, Central South University
1999.5-2000.11 Visiting Scholar at the University of Southern California

Awards

2019-12-30: Lu Hui-Lin Outstanding Teacher Award

Areas of Focus	Pulmonary Fibrosis Lung Injury
Publications	A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice via inhibiting the NLRP3 inflammasome activation and oxidative stress, Hui-Hui Yang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020 Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages, Xiao-Qin Luo, Cha-Xiang Guan, Yong Zhou, 2020 COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence, Chen-Yu Zhang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020 Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China, Li Wan, Cha-Xiang Guan, Gui-Lian Li, 2020 A COX-2/sEH dual inhibitor PTUPB alleviates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress, Yan-Feng Zhang, Chen-Chen Sun, Cha-Xiang Guan, Yong Zhou, 2020 Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition, Ming-Yuan Du, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020 Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells, Min Shao, Cha-Xiang Guan, Yong Zhou, 2019 Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C, Yan-Feng Zhang, Cha-Xiang Guan, Yong Zhou, 2019 Inhibition of glycolysis alleviates lipopolysaccharide-induced acute lung injury in a mouse model, Wen-Jing Zhong, Hui-Hui Yang, Cha-Xiang Guan, Yong Zhou, 2019 Vasoactive intestinal peptide overexpression mediated by lentivirus attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation, Guo-Ying Sun, Cha-Xiang Guan, Yong Zhou, 2018 Soluble epoxide hydrolase inhibitor suppresses the expression of triggering receptor expressed on myeloid cells-1 by inhibiting NF-kB activation in murine macrophage, Liang Dong, Cha-Xiang Guan, 2017 Aucubin alleviates bleomycin-induced pulmonary fibrosis in a mouse model, Yong Zhou, Cha-Xiang Guan, 2017 Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice, Yong Zhou, Cha-Xiang Guan, Jian-Xin Jiang, 2017 Blocking triggering receptor expressed on myeloid cells-1 attenuates lipopolysaccharideinduced acute lung injury via inhibiting NLRP3 inflammasome activation, Tian Liu, Cha-Xiang Guan, 2016 TGF-β1 upregulates the expression of triggering receptor expressed on myeloid cells 1 in murine lungs, Li Peng, Cha-Xiang Guan, Jian-xin Jiang, 2016

Areas of Focus

Pulmonary Fibrosis
Lung Injury

Publications

A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice via inhibiting the NLRP3 inflammasome activation and oxidative stress, Hui-Hui Yang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages, Xiao-Qin Luo, Cha-Xiang Guan, Yong Zhou, 2020
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence, Chen-Yu Zhang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China, Li Wan, Cha-Xiang Guan, Gui-Lian Li, 2020
A COX-2/sEH dual inhibitor PTUPB alleviates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress, Yan-Feng Zhang, Chen-Chen Sun, Cha-Xiang Guan, Yong Zhou, 2020
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition, Ming-Yuan Du, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells, Min Shao, Cha-Xiang Guan, Yong Zhou, 2019
Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C, Yan-Feng Zhang, Cha-Xiang Guan, Yong Zhou, 2019
Inhibition of glycolysis alleviates lipopolysaccharide-induced acute lung injury in a mouse model, Wen-Jing Zhong, Hui-Hui Yang, Cha-Xiang Guan, Yong Zhou, 2019
Vasoactive intestinal peptide overexpression mediated by lentivirus attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation, Guo-Ying Sun, Cha-Xiang Guan, Yong Zhou, 2018
Soluble epoxide hydrolase inhibitor suppresses the expression of triggering receptor expressed on myeloid cells-1 by inhibiting NF-kB activation in murine macrophage, Liang Dong, Cha-Xiang Guan, 2017
Aucubin alleviates bleomycin-induced pulmonary fibrosis in a mouse model, Yong Zhou, Cha-Xiang Guan, 2017
Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice, Yong Zhou, Cha-Xiang Guan, Jian-Xin Jiang, 2017
Blocking triggering receptor expressed on myeloid cells-1 attenuates lipopolysaccharideinduced acute lung injury via inhibiting NLRP3 inflammasome activation, Tian Liu, Cha-Xiang Guan, 2016
TGF-β1 upregulates the expression of triggering receptor expressed on myeloid cells 1 in murine lungs, Li Peng, Cha-Xiang Guan, Jian-xin Jiang, 2016

Pulmonary Fibrosis Lung Injury Pathophysiology Treatment Research Cellular Molecular Mechanisms

Yiming Lu - Shanghai University

Junjie Xiao - Shanghai University

Bai Ping Cui - Shanghai University

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