Areas of Focus
- 肺纤维化
- 肺损伤
Work Experience
- 2019.2-至今 中南大学基础医学院副院长
- 2010.10-2019.1 中南大学继续教育学院副院长
- 2005.12-2010.9 中南大学研究生院副处长
- 2004.6-至今 中南大学基础医学院生理学系教授
- 1999.5-2000.11 美国南加州大学访问学者
Academic Background & Achievements
- 2001-2006 中南大学基础医学博士
- 1987-1990 湖南医科大学基础医学硕士
- 1980-1985 湖南医科大学临床医学学士
- 美国南加州大学访问学者
Publications
- A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice via inhibiting the NLRP3 inflammasome activation and oxidative stress, Hui-Hui Yang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
- Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages, Xiao-Qin Luo, Cha-Xiang Guan, Yong Zhou, 2020
- COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence, Chen-Yu Zhang, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
- Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China, Li Wan, Cha-Xiang Guan, Gui-Lian Li, 2020
- A COX-2/sEH dual inhibitor PTUPB alleviates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress, Yan-Feng Zhang, Chen-Chen Sun, Cha-Xiang Guan, Yong Zhou, 2020
- Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition, Ming-Yuan Du, Jia-Xi Duan, Cha-Xiang Guan, Yong Zhou, 2020
- Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells, Min Shao, Cha-Xiang Guan, Yong Zhou, 2019
- Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C, Yan-Feng Zhang, Cha-Xiang Guan, Yong Zhou, 2019
- Inhibition of glycolysis alleviates lipopolysaccharide-induced acute lung injury in a mouse model, Wen-Jing Zhong, Hui-Hui Yang, Cha-Xiang Guan, Yong Zhou, 2019
- Vasoactive intestinal peptide overexpression mediated by lentivirus attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation, Guo-Ying Sun, Cha-Xiang Guan, Yong Zhou, 2018
- Soluble epoxide hydrolase inhibitor suppresses the expression of triggering receptor expressed on myeloid cells-1 by inhibiting NF-kB activation in murine macrophage, Liang Dong, Cha-Xiang Guan, 2017
- Aucubin alleviates bleomycin-induced pulmonary fibrosis in a mouse model, Yong Zhou, Cha-Xiang Guan, 2017
- Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice, Yong Zhou, Cha-Xiang Guan, Jian-Xin Jiang, 2017
- Blocking triggering receptor expressed on myeloid cells-1 attenuates lipopolysaccharideinduced acute lung injury via inhibiting NLRP3 inflammasome activation, Tian Liu, Cha-Xiang Guan, 2016
- TGF-β1 upregulates the expression of triggering receptor expressed on myeloid cells 1 in murine lungs, Li Peng, Cha-Xiang Guan, Jian-xin Jiang, 2016
Awards
- 2019-12-30: 卢惠霖优秀教师奖
