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Guodong Shen
Mayo Clinic College of Medicine
University of Science and Technology of China
Anhui
Language: Chinese, English
Gastric Cancer
Geriatric Tumors
Targeted Therapy
Sarcopenia
Elderly
Prevention
Tumor-Induced
Skeletal Muscle
Reduction
Mechanism
Areas of Focus
- Mechanism and targeted therapy of gastric cancer and other geriatric tumors
- Mechanism and prevention of sarcopenia in the elderly
- Mechanism and targeted therapy of tumor-induced skeletal muscle reduction
Work Experience
- 2012/08–2014/02 - Anhui Provincial Hospital - Director of Molecular Medicine Laboratory
- 2014/03–2014/09 - Nagoya University, Japan - Senior Researcher
- 2014/09–Present - Anhui Provincial Hospital - Director of Molecular Medicine Laboratory
Academic Background & Achievements
- 2007/09–2010/07 PhD in Pharmacology: Anhui Medical University
- 2010/08–2012/07 Postdoctoral in Cell Biology: University of Science and Technology of China
Publications
- An Fc-muted bispecific antibody targeting PD-L1 and 4-1BB induces antitumor immune activity in colorectal cancer without systemic toxicity., Cheng L, Zhu M, Gao Y, Liu W, Yin W, Zhou P, Zhu Z, Niu L, Zeng X, Zhang D, Fang Q, Wang F, Zhao Q, Zhang Y (*), Shen G (*), 2023
- A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity., Cheng L, Cheng Y, Liu W, Shen A, Zhang D, Xu T, Yin W, Cheng M, Ma X(*), Wang F, Zhao Q, Zeng X, Zhang Y(*), Shen G (*), 2022
- Beyond emotion: online takeaway food consumption is associated with emotional overeating among Chinese college students., Zhang Y(*), Hou F, Yang S, Li J, Zha X (*), Shen G (*), 2022
- The association between leftover food consumption and depression among older adults: Findings from a cross-sectional study., Zhang Y, Hou F, Cheng J, Chen G, Wang L, Jiang X(*), Chen R(*), Shen G (*), 2022
- Depressive symptoms and cognitive decline among Chinese rural elderly individuals: A longitudinal study with 2-year follow-up., Zhou S, Wang Q, Zhang J, Wang Q, Hou F, Han X, Hu S, Shen G (*), Zhang Y (*), 2022
- A WNT7B-m6A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis., Gao Q, Yang L, Shen A, Li Y, Li Y, Hu S, Yang R, Wang X, Yao X(*), Shen G (*), 2021
- ICG-loaded PEG-modified black phosphorus nanosheets for fluorescence imaging-guided breast cancer therapy., Pan W, Chen W, Min Y, Wang J, Yang Z (*), Xu T, Yu F, Shen G (*). Hu Y (*), MA X (*), 2021
- The Wnt3a/β-catenin/TCF7L2 signaling axis reduces the sensitivity of HER2-positive epithelial ovarian cancer to trastuzumab., Shen G (#) (*), Gao Q (#), Liu F (#), Zhang Y, Dai M, Zhao T, Cheng M, Xu T, Jin P, Yin W, Huang D, Weng H, Chen W, Ren H, Mu X, Wu X, Hu S(*), 2020
Awards
- Anhui Science and Technology Award (2022): Third Prize
- Anhui Science and Technology Award (2018): Second Prize
- Anhui Science and Technology Award (2014): Second Prize
- Anhui Youth Science and Technology Award (2013): No rank
- Anhui Science and Technology Award (2012): Second Prize
