Professor | 沈国栋 | 数字化转型顾问

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Name	沈国栋
Contact Information	gdshen@ustc.edu.cn
Language ability	中文, 英语
Province	安徽

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Name

沈国栋

Contact Information

gdshen@ustc.edu.cn

Language ability

中文, 英语

Province

安徽

University/Lab Affiliation and Title	中国科学技术大学
Faculty	Mayo Clinic College of Medicine
Academic Background & Achievements	2007/09–2010/07 博士，药理学：安徽医科大学 2010/08–2012/07 博士后，细胞生物学：中国科学技术大学
Work Experience	2012/08–2014/02 - 安徽省立医院 - 分子医学实验室主任 2014/03–2014/09 - 日本名古屋大学 - 高级研究员 2014/09–至今 - 安徽省立医院 - 分子医学实验室主任
Awards	安徽省科技奖 (2022): 三等奖安徽省科技奖 (2018): 二等奖安徽省科技奖 (2014): 二等奖安徽青年科技奖 (2013): 无等级安徽省科技奖 (2012): 二等奖

University/Lab Affiliation and Title

中国科学技术大学

Faculty

Mayo Clinic College of Medicine

Academic Background & Achievements

2007/09–2010/07 博士，药理学：安徽医科大学
2010/08–2012/07 博士后，细胞生物学：中国科学技术大学

Work Experience

2012/08–2014/02 - 安徽省立医院 - 分子医学实验室主任
2014/03–2014/09 - 日本名古屋大学 - 高级研究员
2014/09–至今 - 安徽省立医院 - 分子医学实验室主任

Awards

安徽省科技奖 (2022): 三等奖
安徽省科技奖 (2018): 二等奖
安徽省科技奖 (2014): 二等奖
安徽青年科技奖 (2013): 无等级
安徽省科技奖 (2012): 二等奖

Areas of Focus	胃癌等老年性肿瘤发病机制及靶向治疗研究老年肌肉减少症发病机制及防治技术研究肿瘤诱导骨骼肌减少机制及靶向治疗研究
Publications	An Fc-muted bispecific antibody targeting PD-L1 and 4-1BB induces antitumor immune activity in colorectal cancer without systemic toxicity., Cheng L, Zhu M, Gao Y, Liu W, Yin W, Zhou P, Zhu Z, Niu L, Zeng X, Zhang D, Fang Q, Wang F, Zhao Q, Zhang Y (), Shen G (), 2023 A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity., Cheng L, Cheng Y, Liu W, Shen A, Zhang D, Xu T, Yin W, Cheng M, Ma X(), Wang F, Zhao Q, Zeng X, Zhang Y(), Shen G (), 2022 Beyond emotion: online takeaway food consumption is associated with emotional overeating among Chinese college students., Zhang Y(), Hou F, Yang S, Li J, Zha X (), Shen G (), 2022 The association between leftover food consumption and depression among older adults: Findings from a cross-sectional study., Zhang Y, Hou F, Cheng J, Chen G, Wang L, Jiang X(), Chen R(), Shen G (), 2022 Depressive symptoms and cognitive decline among Chinese rural elderly individuals: A longitudinal study with 2-year follow-up., Zhou S, Wang Q, Zhang J, Wang Q, Hou F, Han X, Hu S, Shen G (), Zhang Y (), 2022 A WNT7B-m6A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis., Gao Q, Yang L, Shen A, Li Y, Li Y, Hu S, Yang R, Wang X, Yao X(), Shen G (), 2021 ICG-loaded PEG-modified black phosphorus nanosheets for fluorescence imaging-guided breast cancer therapy., Pan W, Chen W, Min Y, Wang J, Yang Z (), Xu T, Yu F, Shen G (). Hu Y (), MA X (), 2021 The Wnt3a/β-catenin/TCF7L2 signaling axis reduces the sensitivity of HER2-positive epithelial ovarian cancer to trastuzumab., Shen G (#) (), Gao Q (#), Liu F (#), Zhang Y, Dai M, Zhao T, Cheng M, Xu T, Jin P, Yin W, Huang D, Weng H, Chen W, Ren H, Mu X, Wu X, Hu S(*), 2020

Areas of Focus

胃癌等老年性肿瘤发病机制及靶向治疗研究
老年肌肉减少症发病机制及防治技术研究
肿瘤诱导骨骼肌减少机制及靶向治疗研究

Publications

An Fc-muted bispecific antibody targeting PD-L1 and 4-1BB induces antitumor immune activity in colorectal cancer without systemic toxicity., Cheng L, Zhu M, Gao Y, Liu W, Yin W, Zhou P, Zhu Z, Niu L, Zeng X, Zhang D, Fang Q, Wang F, Zhao Q, Zhang Y (*), Shen G (*), 2023
A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity., Cheng L, Cheng Y, Liu W, Shen A, Zhang D, Xu T, Yin W, Cheng M, Ma X(*), Wang F, Zhao Q, Zeng X, Zhang Y(*), Shen G (*), 2022
Beyond emotion: online takeaway food consumption is associated with emotional overeating among Chinese college students., Zhang Y(*), Hou F, Yang S, Li J, Zha X (*), Shen G (*), 2022
The association between leftover food consumption and depression among older adults: Findings from a cross-sectional study., Zhang Y, Hou F, Cheng J, Chen G, Wang L, Jiang X(*), Chen R(*), Shen G (*), 2022
Depressive symptoms and cognitive decline among Chinese rural elderly individuals: A longitudinal study with 2-year follow-up., Zhou S, Wang Q, Zhang J, Wang Q, Hou F, Han X, Hu S, Shen G (*), Zhang Y (*), 2022
A WNT7B-m6A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis., Gao Q, Yang L, Shen A, Li Y, Li Y, Hu S, Yang R, Wang X, Yao X(*), Shen G (*), 2021
ICG-loaded PEG-modified black phosphorus nanosheets for fluorescence imaging-guided breast cancer therapy., Pan W, Chen W, Min Y, Wang J, Yang Z (*), Xu T, Yu F, Shen G (*). Hu Y (*), MA X (*), 2021
The Wnt3a/β-catenin/TCF7L2 signaling axis reduces the sensitivity of HER2-positive epithelial ovarian cancer to trastuzumab., Shen G (#) (*), Gao Q (#), Liu F (#), Zhang Y, Dai M, Zhao T, Cheng M, Xu T, Jin P, Yin W, Huang D, Weng H, Chen W, Ren H, Mu X, Wu X, Hu S(*), 2020

胃癌老年性肿瘤靶向治疗肌肉减少症老年预防肿瘤诱导骨骼肌减少机制

邵峰 - 中国科学技术大学

Area of Focus
非编码Rna | 化疗耐药 | 胰腺癌 | 星状细胞 | 癌症进展 | 外泌体 | 诊断 | 靶向治疗 | 机制 | 肿瘤学

吕维富 - 中国科学技术大学

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