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沈国栋
Mayo Clinic College of Medicine
中国科学技术大学
安徽
Language: 中文, 英语
胃癌
老年性肿瘤
靶向治疗
肌肉减少症
老年
预防
肿瘤诱导
骨骼肌
减少
机制
Areas of Focus
- 胃癌等老年性肿瘤发病机制及靶向治疗研究
- 老年肌肉减少症发病机制及防治技术研究
- 肿瘤诱导骨骼肌减少机制及靶向治疗研究
Work Experience
- 2012/08–2014/02 - 安徽省立医院 - 分子医学实验室主任
- 2014/03–2014/09 - 日本名古屋大学 - 高级研究员
- 2014/09–至今 - 安徽省立医院 - 分子医学实验室主任
Academic Background & Achievements
- 2007/09–2010/07 博士，药理学：安徽医科大学
- 2010/08–2012/07 博士后，细胞生物学：中国科学技术大学
Publications
- An Fc-muted bispecific antibody targeting PD-L1 and 4-1BB induces antitumor immune activity in colorectal cancer without systemic toxicity., Cheng L, Zhu M, Gao Y, Liu W, Yin W, Zhou P, Zhu Z, Niu L, Zeng X, Zhang D, Fang Q, Wang F, Zhao Q, Zhang Y (*), Shen G (*), 2023
- A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity., Cheng L, Cheng Y, Liu W, Shen A, Zhang D, Xu T, Yin W, Cheng M, Ma X(*), Wang F, Zhao Q, Zeng X, Zhang Y(*), Shen G (*), 2022
- Beyond emotion: online takeaway food consumption is associated with emotional overeating among Chinese college students., Zhang Y(*), Hou F, Yang S, Li J, Zha X (*), Shen G (*), 2022
- The association between leftover food consumption and depression among older adults: Findings from a cross-sectional study., Zhang Y, Hou F, Cheng J, Chen G, Wang L, Jiang X(*), Chen R(*), Shen G (*), 2022
- Depressive symptoms and cognitive decline among Chinese rural elderly individuals: A longitudinal study with 2-year follow-up., Zhou S, Wang Q, Zhang J, Wang Q, Hou F, Han X, Hu S, Shen G (*), Zhang Y (*), 2022
- A WNT7B-m6A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis., Gao Q, Yang L, Shen A, Li Y, Li Y, Hu S, Yang R, Wang X, Yao X(*), Shen G (*), 2021
- ICG-loaded PEG-modified black phosphorus nanosheets for fluorescence imaging-guided breast cancer therapy., Pan W, Chen W, Min Y, Wang J, Yang Z (*), Xu T, Yu F, Shen G (*). Hu Y (*), MA X (*), 2021
- The Wnt3a/β-catenin/TCF7L2 signaling axis reduces the sensitivity of HER2-positive epithelial ovarian cancer to trastuzumab., Shen G (#) (*), Gao Q (#), Liu F (#), Zhang Y, Dai M, Zhao T, Cheng M, Xu T, Jin P, Yin W, Huang D, Weng H, Chen W, Ren H, Mu X, Wu X, Hu S(*), 2020
Awards
- 安徽省科技奖 (2022): 三等奖
- 安徽省科技奖 (2018): 二等奖
- 安徽省科技奖 (2014): 二等奖
- 安徽青年科技奖 (2013): 无等级
- 安徽省科技奖 (2012): 二等奖
